Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Katharine Westerberg"'
Autor:
Maria P. Lemos, Rena D. Astronomo, Yunda Huang, Sandeep Narpala, Madhu Prabhakaran, Philipp Mann, Carmen A. Paez, Yiwen Lu, Gregory J. Mize, Hayley Glantz, Katharine Westerberg, Hunter Colegrove, Kimberly S. Smythe, Minggang Lin, Robert H. Pierce, Julia Hutter, Ian Frank, John R. Mascola, Adrian B. McDermott, Linda-Gail Bekker, M. Juliana McElrath
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract To prevent sexually-acquired HIV-1 infection by immunoprophylaxis, effective concentrations of broadly neutralizing antibodies are likely needed at mucosal sites of exposure. Here, we examine the biodistribution of monoclonal antibody VRC01
Externí odkaz:
https://doaj.org/article/eb93619de66746c7bd1926ca5ba2800f
Autor:
Yunda Huang, Yiwen Lu, Lamar Ballweber Fleming, Christina Ochsenbauer, Julie Czartoski, Sandeep Narpala, Madhu Prabhakaran, Kelly E. Seaton, Lily Zhang, John Hural, Kenneth H. Mayer, Scott M. Hammer, Lindsey R. Baden, Rena D. Astronomo, Maria P. Lemos, Georgia D. Tomaras, Katharine Westerberg, M. Juliana McElrath, Mary K Gross, Ian Frank, Hong Van Tieu, Adrian B. McDermott, Nicole Grunenberg, Julie E. Ledgerwood
Publikováno v:
J Clin Invest
BACKGROUND: VRC01, a potent, broadly neutralizing monoclonal antibody, inhibits simian-HIV infection in animal models. The HVTN 104 study assessed the safety and pharmacokinetics of VRC01 in humans. We extend the clinical evaluation to determine intr
Autor:
Hua-Xin Liao, Guido Ferrari, Punnee Pitisuttithum, Thomas N. Denny, Justin Pollara, Nicole L. Yates, Georgia D. Tomaras, Florian Hladik, George M. Shaw, Barton F. Haynes, M. Juliana McElrath, Georgeanna Morton, Katharine Westerberg, Tiffany Hensley-McBain, Shi-Mao Xia, Linh Mach, Sampa Santra, Benjamin Mildenberg, Gregory J. Mize, Ranjit Warrier, Rena D. Astronomo, Jaranit Kaewkungwal, Christina Ochsenbauer, Sorachai Nitayapan, Supachai Rerks-Ngarm, Lamar Ballweber-Fleming, Laura L. Sutherland, David C. Montefiori
Publikováno v:
EBioMedicine
HIV-1 infection occurs primarily through mucosal transmission. Application of biologically relevant mucosal models can advance understanding of the functional properties of antibodies that mediate HIV protection, thereby guiding antibody-based vaccin
Autor:
Claire N. Levy, Renan Sauteraud, Johanna Strobl, Florian Hladik, Sean M. Hughes, Lamar Ballweber, Raphael Gottardo, Katharine Westerberg, Sangsoon Woo, Muneesh Tewari, Lucia Vojtech
Publikováno v:
Nucleic Acids Research
Semen contains relatively ill-defined regulatory components that likely aid fertilization, but which could also interfere with defense against infection. Each ejaculate contains trillions of exosomes, membrane-enclosed subcellular microvesicles, whic
Autor:
Caroline M. Mitchell, Leslie McLemore, Kathy Agnew, Rena D. Astronomo, Carolyn Gardella, Matthias Mack, M. Juliana McElrath, Kimberly S. Smythe, Katharine Westerberg, Dorothy L. Patton, Florian Hladik, Amalia Magaret, David A. Eschenbach
Over half of the 33 million people living with human immunodeficiency virus type 1 (HIV-1) in 2009 were women, most of whom were infected through heterosexual intercourse [1]. A possible link between HIV acquisition and use of depot medroxyprogestero
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83daed1e8b0079dea3d3531ba2047782
https://europepmc.org/articles/PMC4172039/
https://europepmc.org/articles/PMC4172039/