Examining acute and chronic effects of short- and long-chain fatty acids on peptide YY (PYY) gene expression, cellular storage and secretion in STC-1 cells

Autor: Christine M. Bruen, Fiona O'Halloran, Danielle Calderwood, Brian D. Green, Harsh Panwar, Linda Giblin, Katharine V. Hand

Publikováno v: European Journal of Nutrition. 52:1303-1313

Peptide YY (PYY) is a gastrointestinal hormone with physiological actions regulating appetite and energy homoeostasis. The cellular mechanisms by which nutrients stimulate PYY secretion from intestinal enteroendocrine cells are still being elucidated

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::532fe4412d1adadd8a1c6314f94f876b
https://doi.org/10.1007/s00394-012-0439-9

Investigating the effects of physiological bile acids on GLP-1 secretion and glucose tolerance in normal and GLP-1R(-/-) mice

Autor: Katharine V. Hand, EP Rafferty, A.R.G. Wylie, Christopher Elliott, David J. Grieve, Brian D. Green

Publikováno v: Rafferty, E P, Wylie, A R, Hand, K H, Elliott, C E, Grieve, D J & Green, B D 2011, ' Investigating the effects of physiological bile acids on GLP-1 secretion and glucose tolerance in normal and GLP-1R(-/-) mice ', Biological Chemistry, vol. 392, no. 6, pp. 539-546 . https://doi.org/10.1515/BC.2011.050

Physiological secretion of bile acids has previously been linked to the regulation of blood glucose. GLP-1 is an intestinal peptide hormone with important glucose-lowering actions, such as stimulation of insulin secretion and inhibition of glucagon s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7119258bb17ab07d26bcacfa49b178ec
https://pubmed.ncbi.nlm.nih.gov/21521075

GLP-1 and related peptides cause concentration-dependent relaxation of rat aorta through a pathway involving KATP and cAMP

Autor: David J. Grieve, Brian D. Green, Katharine V. Hand, Roslyn S. Cassidy, Bronagh McDonnell, Janette E. Dougan

Publikováno v: Green, B D, Hand, K V, Dougan, J E, McDonnell, B M, Cassidy, R S & Grieve, D J 2008, ' GLP-1 and related peptides cause concentration-dependent relaxation of rat aorta through a pathway involving K ATP and cAMP ' Archives of Biochemistry and Biophysics, vol 478, no. 2, pp. 136-142 . DOI: 10.1016/j.abb.2008.08.001

increasing evidence from both clinical and experimental studies indicates that the insulin-releasing hormone, glucagon-like peptide-1 (GLP-1) may exert additional protective/reparative effects on the cardiovascular system. The aim of this study was t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75b75af7342719d1d20835eeb12271fc
https://pure.qub.ac.uk/portal/en/publications/glp1-and-related-peptides-cause-concentrationdependent-relaxation-of-rat-aorta-through-a-pathway-involving-katp-and-camp(38a55722-00b8-4c91-bdb9-4aedbd5e00db).html

Acute and chronic effects of dietary fatty acids on cholecystokinin expression, storage and secretion in enteroendocrine STC-1 cells.

Autor: Hand, Katharine V., Bruen, Christine M., O'Halloran, Fiona, Giblin, Linda, Green, Brian D.

Publikováno v: Molecular Nutrition & Food Research; May2010 Supplement, Vol. 54, pS93-S103, 11p