Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Katharine S Dobb"'
Autor:
Katharine S Dobb, Sarah J Kaye, Nicola Beckmann, John L Thain, Lubomira Stateva, Mike Birch, Jason D Oliver
Publikováno v:
PLoS ONE, Vol 10, Iss 11, p e0143770 (2015)
Antifungal drugs acting via new mechanisms of action are urgently needed to combat the increasing numbers of severe fungal infections caused by pathogens such as Candida albicans. The phosphopantetheinyl transferase of Aspergillus fumigatus, encoded
Externí odkaz:
https://doaj.org/article/1cd24085abc54adea0bfd6032719577a
Autor:
Anna Johns, Daniel H. Scharf, Fabio Gsaller, Hella Schmidt, Thorsten Heinekamp, Maria Straßburger, Jason D. Oliver, Mike Birch, Nicola Beckmann, Katharine S. Dobb, Jane Gilsenan, Bharatkumar Rash, Elaine Bignell, Axel A. Brakhage, Michael J. Bromley
Publikováno v:
mBio, Vol 8, Iss 4 (2017)
ABSTRACT Secondary metabolites are key mediators of virulence for many pathogens. Aspergillus fumigatus produces a vast array of these bioactive molecules, the biosynthesis of which is catalyzed by nonribosomal peptide synthetases (NRPSs) or polyketi
Externí odkaz:
https://doaj.org/article/cccea62e55644309b3c3b177d1c49935
Autor:
Martin J. Slater, Graham Edward Morris Sibley, Jason David Oliver, Laura McEntee, Nathan P. Wiederhold, Nicola Beckmann, Katharine S. Dobb, Michael Bromley, Anthony J. Kennedy, Joanne Livermore, Saskia du Pré, William W. Hope, Mike Birch, Derek Law
Publikováno v:
Oliver, J D, Sibley, G E M, Beckmann, N, Dobb, K S, Slater, M J, McEntee, L, Du Pre, S, Livermore, J, Bromley, M, Wiederhold, N P, Hope, W W, Kennedy, A J, Law, D & Birch, M 2016, ' F901318 represents a novel class of antifungal drug that inhibits dihydroorotate dehydrogenase ', Proceedings of the National Academy of Sciences of the United States of America, vol. 113, no. 45, pp. 12809–12814 . https://doi.org/10.1073/pnas.1608304113
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
There is an important medical need for new antifungal agents with novel mechanisms of action to treat the increasing number of patients with life-threatening systemic fungal disease and to overcome the growing problem of resistance to current therapi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cfb38951d6bd7f059c30f0b5a34337ce
https://www.research.manchester.ac.uk/portal/en/publications/f901318-represents-a-novel-class-of-antifungal-drug-that-inhibits-dihydroorotate-dehydrogenase(9cb751b0-e1f3-483a-8bda-db1263b306cc).html
https://www.research.manchester.ac.uk/portal/en/publications/f901318-represents-a-novel-class-of-antifungal-drug-that-inhibits-dihydroorotate-dehydrogenase(9cb751b0-e1f3-483a-8bda-db1263b306cc).html
Autor:
Sarah J. Kaye, Katharine S. Dobb, John Leslie Thain, Lubomira Stateva, Jason David Oliver, Mike Birch, Nicola Beckmann
Publikováno v:
PLoS ONE, Vol 10, Iss 11, p e0143770 (2015)
PLoS ONE
PLoS ONE
Antifungal drugs acting via new mechanisms of action are urgently needed to combat the increasing numbers of severe fungal infections caused by pathogens such as Candida albicans. The phosphopantetheinyl transferase of Aspergillus fumigatus, encoded
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2564b425659c871738c7c11e169fa4c8
http://europepmc.org/articles/PMC4659657?pdf=render
http://europepmc.org/articles/PMC4659657?pdf=render