Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Katharine H D, Crawford"'
Autor:
Adam S. Dingens, Katharine H. D. Crawford, Amanda Adler, Sarah L. Steele, Kirsten Lacombe, Rachel Eguia, Fatima Amanat, Alexandra C. Walls, Caitlin R. Wolf, Michael Murphy, Deleah Pettie, Lauren Carter, Xuan Qin, Neil P. King, David Veesler, Florian Krammer, Jane A. Dickerson, Helen Y. Chu, Janet A. Englund, Jesse D. Bloom
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-6 (2020)
COVID-19 disease is less common in children than adults, but the extent to which SARS-CoV-2 infections are missed through symptom-driven testing is not well understood. In this study, the authors show that approximately 1% of children seeking care fo
Externí odkaz:
https://doaj.org/article/399ad20101ad4ac9854352e24ec39d01
Autor:
Daniel Ellis, Natalie Brunette, Katharine H. D. Crawford, Alexandra C. Walls, Minh N. Pham, Chengbo Chen, Karla-Luise Herpoldt, Brooke Fiala, Michael Murphy, Deleah Pettie, John C. Kraft, Keara D. Malone, Mary Jane Navarro, Cassandra Ogohara, Elizabeth Kepl, Rashmi Ravichandran, Claire Sydeman, Maggie Ahlrichs, Max Johnson, Alyssa Blackstone, Lauren Carter, Tyler N. Starr, Allison J. Greaney, Kelly K. Lee, David Veesler, Jesse D. Bloom, Neil P. King
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
The unprecedented global demand for SARS-CoV-2 vaccines has demonstrated the need for highly effective vaccine candidates that are thermostable and amenable to large-scale manufacturing. Nanoparticle immunogens presenting the receptor-binding domain
Externí odkaz:
https://doaj.org/article/ee4c16cc940d4a98bc65cf319a369f9a
Autor:
Rachel T Eguia, Katharine H D Crawford, Terry Stevens-Ayers, Laurel Kelnhofer-Millevolte, Alexander L Greninger, Janet A Englund, Michael J Boeckh, Jesse D Bloom
Publikováno v:
PLoS Pathogens, Vol 17, Iss 4, p e1009453 (2021)
There is intense interest in antibody immunity to coronaviruses. However, it is unknown if coronaviruses evolve to escape such immunity, and if so, how rapidly. Here we address this question by characterizing the historical evolution of human coronav
Externí odkaz:
https://doaj.org/article/b0411573015b4743ab53aa2f4aedcd83
Autor:
Caelan E. Radford, Philipp Schommers, Lutz Gieselmann, Katharine H. D. Crawford, Bernadeta Dadonaite, Timothy C. Yu, Adam S. Dingens, Julie Overbaugh, Florian Klein, Jesse D. Bloom
Publikováno v:
bioRxiv
Understanding the specificities of human serum antibodies that broadly neutralize HIV can inform prevention and treatment strategies. Here we describe a deep mutational scanning system that can measure the effects of combinations of mutations to HIV
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb0478771c3ce8ea4658bb2834d04090
https://europepmc.org/articles/PMC10055425/
https://europepmc.org/articles/PMC10055425/
Autor:
Andrea N. Loes, Lauren E. Gentles, Allison J. Greaney, Katharine H. D. Crawford, Jesse D. Bloom
Publikováno v:
Viruses, Vol 12, Iss 9, p 987 (2020)
An effective vaccine is essential for controlling the spread of the SARS-CoV-2 virus. Here, we describe an influenza virus-based vaccine for SARS-CoV-2. We incorporated a membrane-anchored form of the SARS-CoV-2 spike receptor binding domain (RBD) in
Externí odkaz:
https://doaj.org/article/a81ba677af6b4bf286a8a79e248c7f43
Autor:
Katharine H. D. Crawford, Rachel Eguia, Adam S. Dingens, Andrea N. Loes, Keara D. Malone, Caitlin R. Wolf, Helen Y. Chu, M. Alejandra Tortorici, David Veesler, Michael Murphy, Deleah Pettie, Neil P. King, Alejandro B. Balazs, Jesse D. Bloom
Publikováno v:
Viruses, Vol 12, Iss 5, p 513 (2020)
SARS-CoV-2 enters cells using its Spike protein, which is also the main target of neutralizing antibodies. Therefore, assays to measure how antibodies and sera affect Spike-mediated viral infection are important for studying immunity. Because SARS-Co
Externí odkaz:
https://doaj.org/article/88a2dcbba5204bbe892d526add0ceb42
Autor:
Bernadeta Dadonaite, Katharine H D Crawford, Caelan E Radford, Ariana G Farrell, Timothy C Yu, William W Hannon, Panpan Zhou, Raiees Andrabi, Dennis R Burton, Lihong Liu, David D. Ho, Richard A. Neher, Jesse D Bloom
Publikováno v:
bioRxiv
A major challenge in understanding SARS-CoV-2 evolution is interpreting the antigenic and functional effects of emerging mutations in the viral spike protein. Here we describe a new deep mutational scanning platform based on non-replicative pseudotyp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21b9ff3a1fcade6fdf7b7b300eb18831
https://europepmc.org/articles/PMC9580381/
https://europepmc.org/articles/PMC9580381/
Autor:
Jesse D. Bloom, Michael J. Boeckh, Janet A. Englund, Alexander L. Greninger, Laurel Kelnhofer-Millevolte, Terry Stevens-Ayers, Katharine H. D. Crawford, Rachel Eguia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::55e37c8b246c8ec13251c9f87473e7fd
https://doi.org/10.15252/rc.2022936750
https://doi.org/10.15252/rc.2022936750
Autor:
Emma B, Hodcroft, Moira, Zuber, Sarah, Nadeau, Timothy G, Vaughan, Katharine H D, Crawford, Christian L, Althaus, Martina L, Reichmuth, John E, Bowen, Alexandra C, Walls, Davide, Corti, Jesse D, Bloom, David, Veesler, David, Mateo, Alberto, Hernando, Iñaki, Comas, Fernando, González Candelas, Tanja, Stadler, Richard A, Neher
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
instname
A variant of SARS-CoV-2 emerged in early summer 2020, presumably in Spain, and has since spread to multiple European countries. The variant was first observed in Spain in June and has been at frequencies above 40% since July. Outside of Spain, the fr
Autor:
Emma B, Hodcroft, Moira, Zuber, Sarah, Nadeau, Timothy G, Vaughan, Katharine H D, Crawford, Christian L, Althaus, Martina L, Reichmuth, John E, Bowen, Alexandra C, Walls, Davide, Corti, Jesse D, Bloom, David, Veesler, David, Mateo, Alberto, Hernando, Iñaki, Comas, Fernando, González-Candelas, Tanja, Stadler, Mónica, Parra-Grande
Publikováno v:
medRxiv
article-version (status) pre
article-version (number) 2
article-version (status) pre
article-version (number) 2
Following its emergence in late 2019, SARS-CoV-2 has caused a global pandemic resulting in unprecedented efforts to reduce transmission and develop therapies and vaccines (WHO Emergency Committee, 2020; Zhu et al., 2020). Rapidly generated viral geno