Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Katharine E Halligan"'
Autor:
Katharine E Halligan, Antony Michealraj Kulandaimanuvel, Andrea Cruz, James T Felker, Craig Daniels, Michael D Taylor, Sameer Agnihotri
Publikováno v:
Glioma, Vol 4, Iss 4, Pp 85-91 (2021)
Ependymomas are a lethal central nervous system (CNS) tumor found in both adults and children. Recent efforts have focused on risk stratification by classifying the molecular variants of CNS ependymoma. Despite this increased knowledge of molecular d
Externí odkaz:
https://doaj.org/article/bcf035cbcba44566ab7567b6fdc04076
Autor:
Matthew Hickling, Lauren Weintraub, Anne Nepo, Natasha Shur, Nathan Menaker, John Paige, Katharine E. Halligan
Publikováno v:
Journal of pediatric hematology/oncology. 39(3)
This case report details a unique case of acute, reversible liver failure in a 12-year-old male with sickle cell anemia on chronic transfusion protocol and deferasirox chelation. There is substantial literature documenting deferasirox-induced renal i
Autor:
Lauren Weintraub, Roshal R. Patel, Jeffrey S. Ross, Katharine E. Halligan, Shakti H. Ramkissoon
Publikováno v:
Neuro-Oncology. 20:i181-i182
Tumor mutational burden (TMB) and driver mutations are potential biomarkers to predict efficacy of immune checkpoint inhibitors (ICPI). Studies demonstrated malignant gliomas with high TMB in children and adults may preferentially benefit from treatm
Autor:
Katharine E. Halligan, Mohamed Trebak, Peter A. Vincent, Guoqing Hu, Xuexin Zhang, José C. González-Cobos, Margarida Barroso, Jiliang Zhou, Khalid Matrougui, Harold A. Singer, Wei Zhang, Jonathan M. Bisaillon, Rajender K. Motiani
Publikováno v:
Circulation Research. 109:534-542
Rationale: The molecular correlate of the calcium release-activated calcium current ( I CRAC ), the channel protein Orai1, is upregulated in proliferative vascular smooth muscle cells (VSMC). However, the role of Orai1 in vascular disease remains lar
Autor:
Harold A. Singer, Mohamed Trebak, David Jourd'heuil, Katharine E. Halligan, José C. González-Cobos, Jonathan M. Bisaillon, Rajender K. Motiani, Marie Potier, Wael F. Alzawahra, Margarida Barroso
Publikováno v:
American Journal of Physiology-Cell Physiology. 298:C993-C1005
We recently demonstrated that thapsigargin-induced passive store depletion activates Ca2+ entry in vascular smooth muscle cells (VSMC) through stromal interaction molecule 1 (STIM1)/Orai1, independently of transient receptor potential canonical (TRPC
Publikováno v:
The FASEB Journal. 23
Publikováno v:
The Journal of biological chemistry. 284(13)
Disposition of the second messenger nitric oxide (NO) in mammalian tissues occurs through multiple pathways including dioxygenation by erythrocyte hemoglobin and red muscle myoglobin. Metabolism by a putative NO dioxygenase activity in non-striated t
Autor:
David Jourd'heuil, Katharine E. Halligan, Benjamin J. Guikema, Roman Ginnan, Harold A. Singer
Inflammation plays a critical role in promoting smooth muscle migration and proliferation during vascular diseases such as post-angioplasty restenosis and atherosclerosis. Another common feature of many vascular diseases is the contribution of reacti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be5f1a337c6f80295a9fb000b438c5f2
https://europepmc.org/articles/PMC2390910/
https://europepmc.org/articles/PMC2390910/
Autor:
Frances L. Jourd'heuil, Katharine E. Halligan, David Jourd'heuil, Wael Alzawahara, Mohamed Trebak, Wei Zhang, Harold A. Singer, Diane V. Singer
Publikováno v:
Free Radical Biology and Medicine. 65:S73
Autor:
Mohamed Trebak, Keneta McKellar, Harold A. Singer, David Jourd'heuil, Wei Zhang, Katharine E. Halligan, Wael Alzawahara, Frances L. Jourd'heuil
Publikováno v:
Free Radical Biology and Medicine. 53:S165