Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Katharine C. Abruzzi"'
Autor:
Dingbang Ma, Dariusz Przybylski, Katharine C Abruzzi, Matthias Schlichting, Qunlong Li, Xi Long, Michael Rosbash
Publikováno v:
eLife, Vol 10 (2021)
Many different functions are regulated by circadian rhythms, including those orchestrated by discrete clock neurons within animal brains. To comprehensively characterize and assign cell identity to the 75 pairs of Drosophila circadian neurons, we opt
Externí odkaz:
https://doaj.org/article/30565948e29e41ffaa9a492ecc5cd798
Autor:
Dingbang Ma, Nicholas Herndon, Jasmine Quynh Le, Katharine C. Abruzzi, Kai Zinn, Michael Rosbash
Publikováno v:
Science Advances. 9
Our recent single-cell sequencing of most adult Drosophila circadian neurons indicated notable and unexpected heterogeneity. To address whether other populations are similar, we sequenced a large subset of adult brain dopaminergic neurons. Their gene
RNA binding proteins (RBPs) perform a myriad of functions and are implicated in numerous neurological diseases. To identify the targets of RBPs in small numbers of cells, we developed TRIBE, in which the catalytic domain of the RNA editing enzyme ADA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3ae01572ecbb094b0296ec0d05cbe943
https://doi.org/10.1101/2023.02.03.527025
https://doi.org/10.1101/2023.02.03.527025
Publikováno v:
eLife, Vol 7 (2018)
Although alternative pre-mRNA splicing (AS) significantly diversifies the neuronal proteome, the extent of AS is still unknown due in part to the large number of diverse cell types in the brain. To address this complexity issue, we used an annotation
Externí odkaz:
https://doaj.org/article/9189de5f2ff0445886f559cc5546b678
Autor:
Katharine C Abruzzi, Abigail Zadina, Weifei Luo, Evelyn Wiyanto, Reazur Rahman, Fang Guo, Orie Shafer, Michael Rosbash
Publikováno v:
PLoS Genetics, Vol 13, Iss 2, p e1006613 (2017)
Locomotor activity rhythms are controlled by a network of ~150 circadian neurons within the adult Drosophila brain. They are subdivided based on their anatomical locations and properties. We profiled transcripts "around the clock" from three key grou
Externí odkaz:
https://doaj.org/article/3bae614a9ea7447d8078fac31026c506
Our recent single cell sequencing of most adult Drosophila circadian neurons indicated striking gene expression heterogeneity, about 2-3 cells per clock neuron group. To extend this characterization to other adult fly brain neurons, we used the ident
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8576f2ef8a32e62bac497900ae024397
https://doi.org/10.1101/2022.04.22.489196
https://doi.org/10.1101/2022.04.22.489196
Publikováno v:
Science (New York, N.Y.). 372(6539)
Ray
Autor:
Matthias Schlichting, Qunlong Li, Dariusz Przybylski, Dingbang Ma, Xi Long, Katharine C. Abruzzi, Michael Rosbash
Many different functions are regulated by circadian rhythms, including those orchestrated by discrete clock neurons within animal brains. To comprehensively characterize and assign cell identity to the 75 pairs ofDrosophilacircadian neurons, we optim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f75a25155cd048576cb3da5b7f02a802
https://doi.org/10.1101/2020.09.15.297051
https://doi.org/10.1101/2020.09.15.297051
Autor:
Dingbang, Ma, Dariusz, Przybylski, Katharine C, Abruzzi, Matthias, Schlichting, Qunlong, Li, Xi, Long, Michael, Rosbash
Publikováno v:
eLife
Many different functions are regulated by circadian rhythms, including those orchestrated by discrete clock neurons within animal brains. To comprehensively characterize and assign cell identity to the 75 pairs of Drosophila circadian neurons, we opt