Zobrazeno 1 - 10 of 25 pro vyhledávání: '"Katharine Briggs"'
1
Akademický článek
eTRANSAFE: Building a sustainable framework to share reproducible drug safety knowledge with the public domain [version 1; peer review: 2 approved]
Autor: Katharina B. Lauer, John-Michael Sauer, Richard Liwski, Niklas Blomberg, Miranda Mourby, Montse Camprubi, Sirarat Sarntivijai, Katharine Briggs, Thomas Steger-Hartmann, Johan van der Lei, Alison Cave
Publikováno v: F1000Research, Vol 11 (2022)
Integrative drug safety research in translational health informatics has rapidly evolved and included data that are drawn in from many resources, combining diverse data that are either reused from (curated) repositories, or newly generated at source.
Externí odkaz: https://doaj.org/article/fdab4225b8f14c9f93a0b10bf9a470c8
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3
Akademický článek
Value of shared preclinical safety studies – The eTOX database
Autor: Katharine Briggs, Chris Barber, Montserrat Cases, Philippe Marc, Thomas Steger-Hartmann
Publikováno v: Toxicology Reports, Vol 2, Iss C, Pp 210-221 (2015)
A first analysis of a database of shared preclinical safety data for 1214 small molecule drugs and drug candidates extracted from 3970 reports donated by thirteen pharmaceutical companies for the eTOX project (www.etoxproject.eu) is presented. Specie
Externí odkaz: https://doaj.org/article/7f023416977c430288c2eda1c173f9c0
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4
Akademický článek
The eTOX Data-Sharing Project to Advance in Silico Drug-Induced Toxicity Prediction
Autor: Montserrat Cases, Katharine Briggs, Thomas Steger-Hartmann, François Pognan, Philippe Marc, Thomas Kleinöder, Christof H. Schwab, Manuel Pastor, Jörg Wichard, Ferran Sanz
Publikováno v: International Journal of Molecular Sciences, Vol 15, Iss 11, Pp 21136-21154 (2014)
The high-quality in vivo preclinical safety data produced by the pharmaceutical industry during drug development, which follows numerous strict guidelines, are mostly not available in the public domain. These safety data are sometimes published as a
Externí odkaz: https://doaj.org/article/7a907e1dda6a465797e0759489e8220b
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5
Akademický článek
Inroads to Predict in Vivo Toxicology—An Introduction to the eTOX Project
Autor: Jörg D. Wichard, Thomas Steger-Hartmann, Andreas Sutter, David K. Watson, Manuel Pastor, François Pognan, Ferran Sanz, Christof H. Schwab, David J. Heard, Montserrat Cases, Katharine Briggs
Publikováno v: International Journal of Molecular Sciences, Vol 13, Iss 3, Pp 3820-3846 (2012)
There is a widespread awareness that the wealth of preclinical toxicity data that the pharmaceutical industry has generated in recent decades is not exploited as efficiently as it could be. Enhanced data availability for compound comparison (“read-
Externí odkaz: https://doaj.org/article/ec609ff085e0487fa4342a7d028382c1
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6
Guidelines for FAIR sharing of preclinical safety and off-target pharmacology data
Autor: Francois Pognan, Phil Drew, Nicolas Bosc, Tima Camara, Jan A. Kors, Katharine Briggs, Sirarat Sarntivijai, Manuel Pastor, William C Drewe, Thomas Steger-Hartmann, Erik M. van Mulligen, Carlos Díaz, Jordi Quintana
Publikováno v: Altex, 38(2), 187-197. Springer International Publishing AG
ALTEX
Pre-competitive data sharing can offer the pharmaceutical industry significant benefits in terms of reducing the time and costs involved in getting a new drug to market through more informed testing strategies and knowledge gained by pooling data. If
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e61c505267ac8b6fa0b42d47100c81a2
https://pure.eur.nl/en/publications/4b47b5e2-cf7d-45f0-830a-ba1cdcccfc95
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