Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Katharina Wolfrum"'
Autor:
Nancy Mah, Ying Wang, Mei-Chih Liao, Alessandro Prigione, Justyna Jozefczuk, Björn Lichtner, Katharina Wolfrum, Manuela Haltmeier, Max Flöttmann, Martin Schaefer, Alexander Hahn, Ralf Mrowka, Edda Klipp, Miguel A Andrade-Navarro, James Adjaye
Publikováno v:
PLoS ONE, Vol 6, Iss 8, p e24351 (2011)
Somatic cells can be reprogrammed to induced pluripotent stem cells by over-expression of OCT4, SOX2, KLF4 and c-MYC (OSKM). With the aim of unveiling the early mechanisms underlying the induction of pluripotency, we have analyzed transcriptional pro
Externí odkaz:
https://doaj.org/article/6f327d3667594fcfaf6742fcb40f8a79
Publikováno v:
PLoS ONE, Vol 5, Iss 10, p e13703 (2010)
Human amniotic fluid cells (AFCs) are routinely obtained for prenatal diagnostics procedures. Recently, it has been illustrated that these cells may also serve as a valuable model system to study developmental processes and for application in regener
Externí odkaz:
https://doaj.org/article/a3ee3ce723c045bdbe70efa1c69ee967
Autor:
Anja Voigt, Michael Ristow, Pablo Steinberg, René Thierbach, Simone Florian, Katharina Wolfrum, Peter Bannasch, Urte Blume, Gunnar Drewes
Publikováno v:
Human Molecular Genetics. 21:656-663
Friedreich's ataxia is an inherited neurodegenerative disease caused by the reduced expression of the mitochondrially active protein frataxin. We have previously shown that mice with a hepatocyte-specific frataxin knockout (AlbFxn(-/-)) develop multi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c13d45a29818d388260bd8f9e47fa2e7
https://doi.org/10.1093/hmg/ddr499
https://doi.org/10.1093/hmg/ddr499
Autor:
Nancy Mah, Katharina Wolfrum, Ying Wang, Miguel A. Andrade-Navarro, James Adjaye, Alessandro Prigione
Publikováno v:
Stem Cell Reviews and Reports. 6:282-296
Human embryonic stem (ES) cells possess an enormous potential for applications in regenerative medicine. However, these cells have several inevitable hurdles limiting their clinical applications, such as transplant rejection and embryo destruction. A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e9e04ea60d9783d499a2118143aa2ce
https://doi.org/10.1007/s12015-010-9137-2
https://doi.org/10.1007/s12015-010-9137-2
Autor:
Joseph Demeester, Joanna Rejman, Geertrui Tavernier, Stefaan C. De Smedt, James Adjaye, Katharina Wolfrum
Publikováno v:
Biomaterials
The first successful reprogramming of differentiated cells to a pluripotent state was done by retroviral introduction of four transcription factors (Oct4, Sox2, Klf4, cMyc) by the group of Yamanaka in 2006. Since then, scientists all over the world h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::382c3b505ef5f30a01fb00638355a737
https://hdl.handle.net/11858/00-001M-0000-000E-F4EF-A11858/00-001M-0000-000E-F0A9-F
https://hdl.handle.net/11858/00-001M-0000-000E-F4EF-A11858/00-001M-0000-000E-F0A9-F
Molecular insights into reprogramming-initiation events mediated by the OSKM gene regulatory network
Autor:
Björn Lichtner, Ying Wang, Alexander Hahn, Edda Klipp, Ralf Mrowka, Justyna Jozefczuk, Mei-Chih Liao, Alessandro Prigione, James Adjaye, Katharina Wolfrum, Manuela Haltmeier, Max Flöttmann, Martin Schaefer, Nancy Mah, Miguel A. Andrade-Navarro
Publikováno v:
PLoS ONE, Vol 6, Iss 8, p e24351 (2011)
PLoS ONE
PLoS ONE
Somatic cells can be reprogrammed to induced pluripotent stem cells by over-expression of OCT4, SOX2, KLF4 and c-MYC (OSKM). With the aim of unveiling the early mechanisms underlying the induction of pluripotency, we have analyzed transcriptional pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac15e3797bd53c1767b1dda895103386
http://europepmc.org/articles/PMC3164204?pdf=render
http://europepmc.org/articles/PMC3164204?pdf=render
Autor:
Katharina, Wolfrum, Ying, Wang, Alessandro, Prigione, Karl, Sperling, Hans, Lehrach, James, Adjaye
Publikováno v:
PLoS ONE, Vol 5, Iss 10, p e13703 (2010)
PLoS ONE
PLoS ONE
Human amniotic fluid cells (AFCs) are routinely obtained for prenatal diagnostics procedures. Recently, it has been illustrated that these cells may also serve as a valuable model system to study developmental processes and for application in regener
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::9025776c02f56912da3d1c139b003763
http://edoc.mdc-berlin.de/13742/1/13742oa.pdf
http://edoc.mdc-berlin.de/13742/1/13742oa.pdf