Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Katharina Waniek"'
Autor:
Stefanie Lerche, Milan Zimmermann, Benjamin Roeben, Isabel Wurster, Franca Laura Fries, Christian Deuschle, Katharina Waniek, Ingolf Lachmann, Meike Jakobi, Thomas O. Joos, Thomas Knorpp, Nicole Schneiderhan-Marra, Kathrin Brockmann
Publikováno v:
npj Parkinson's Disease, Vol 9, Iss 1, Pp 1-12 (2023)
Abstract Inflammation modifies the incidence and progression of Parkinson’s disease (PD). By using 30 inflammatory markers in CSF in 498 people with PD and 67 people with dementia with Lewy bodies (DLB) we show that: (1) levels of ICAM-1, Interleuk
Externí odkaz:
https://doaj.org/article/10293bd7e8d6473fbc25141674fa7271
Autor:
Isabel Wurster, Corinne Quadalti, Marcello Rossi, Ann-Kathrin Hauser, Christian Deuschle, Claudia Schulte, Katharina Waniek, Ingolf Lachmann, Christian la Fougere, Kathrin Doppler, Thomas Gasser, Benjamin Bender, Piero Parchi, Kathrin Brockmann
Publikováno v:
npj Parkinson's Disease, Vol 8, Iss 1, Pp 1-8 (2022)
Abstract Lewy-body pathology with aggregation of abnormal conformations of the protein alpha-synuclein (α-Syn) represent the histopathological hallmarks of Parkinson’s disease (PD). Genetic prototypes such as PD due to mutations in the alpha-synuc
Externí odkaz:
https://doaj.org/article/fe2bc764d81a41cfa96c02a1c8680740
Autor:
Kathrin Brockmann, Corinne Quadalti, Stefanie Lerche, Marcello Rossi, Isabel Wurster, Simone Baiardi, Benjamin Roeben, Angela Mammana, Milan Zimmermann, Ann-Kathrin Hauser, Christian Deuschle, Claudia Schulte, Katharina Waniek, Ingolf Lachmann, Simon Sjödin, Ann Brinkmalm, Kaj Blennow, Henrik Zetterberg, Thomas Gasser, Piero Parchi
Publikováno v:
Acta Neuropathologica Communications, Vol 9, Iss 1, Pp 1-11 (2021)
Abstract The clinicopathological heterogeneity in Lewy-body diseases (LBD) highlights the need for pathology-driven biomarkers in-vivo. Misfolded alpha-synuclein (α-Syn) is a lead candidate based on its crucial role in disease pathophysiology. Real-
Externí odkaz:
https://doaj.org/article/458a88532d6e4fe5b0fad935d77979a7
Autor:
Stefanie Lerche, Milan Zimmermann, Isabel Wurster, Benjamin Roeben, Franca Laura Fries, Christian Deuschle, Katharina Waniek, Ingolf Lachmann, Thomas Gasser, Meike Jakobi, Thomas O. Joos, Nicole Schneiderhan-Marra, Kathrin Brockmann
Publikováno v:
Frontiers in Neurology, Vol 13 (2022)
BackgroundAn involvement of the central-nervous and peripheral, innate and adaptive immune system in the pathogenesis of Parkinson's disease (PD) is nowadays well established.ObjectivesWe face several open questions in preparation of clinical trials
Externí odkaz:
https://doaj.org/article/a03fb7f37be348319ac70ec322483f47
Autor:
Lilian Calderón-Garcidueñas, Elijah W. Stommel, Ingolf Lachmann, Katharina Waniek, Chih-Kai Chao, Angélica González-Maciel, Edgar García-Rojas, Ricardo Torres-Jardón, Ricardo Delgado-Chávez, Partha S. Mukherjee
Publikováno v:
Toxics, Vol 10, Iss 10, p 559 (2022)
Environmental exposures to fine particulate matter (PM2.5) and ultrafine particle matter (UFPM) are associated with overlapping Alzheimer’s, Parkinson’s and TAR DNA-binding protein 43 (TDP-43) hallmark protein pathologies in young Metropolitan Me
Externí odkaz:
https://doaj.org/article/af27ac321cea462b87ba00c7429c68ec
Autor:
Kathrin Brockmann, Stefanie Lerche, Milan Zimmermann, Benjamin Roeben, Isabel Wurster, Franca Fries, Christian Deuschle, Katharina Waniek, Ingolf Lachmann, Meike Jakobi, Thomas Joos, Nicole Schneiderhan-Marra, Thomas Knorpp
Publikováno v:
npj Parkinson's Disease 9(1), 38 (2023). doi:10.1038/s41531-023-00476-2
Inflammation modifies the incidence and progression of Parkinson’s disease (PD). By using 30 inflammatory markers in CSF in 498 people with PD and 67 people with dementia with Lewy bodies (DLB) we show that: (1) levels of ICAM-1, Interleukin-8, MCP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::345b7310af79d8c3cacbaa953c54695c
Autor:
Rudolf Schipfer, Gabriel Glotz, Anton Arzt, C. Oliver Kappe, Clemens Stueckler, David Cantillo, Rupert J. Baumgartner, Andreas Gollner, Katharina Waniek, Josef-Peter Schöggl
Publikováno v:
Organic Process Research & Development. 25:2367-2379
Autor:
Simon Sjödin, Isabel Wurster, Kathrin Brockmann, Henrik Zetterberg, Thomas Gasser, Inga Liepelt-Scarfone, Kaj Blennow, Ann Brinkmalm, Benjamin Roeben, Stefanie Lerche, Ann-Kathrin Hauser, Ingolf Lachmann, Milan Zimmermann, Katharina Waniek
Publikováno v:
Movement disorders 36(11), 2595-2604 (2021). doi:10.1002/mds.28704
Background Molecular pathways associated with α-synuclein proteostasis have been detected in genetic studies and in cell models and include autophagy, ubiquitin-proteasome system, mitochondrial homeostasis, and synaptic plasticity. However, we lack
Autor:
Christian Deuschle, Inga Liepelt-Scarfone, Gerrit Machetanz, Michelle M. Mielke, Ingolf Lachmann, Ruby Chiang, Claudia Schulte, Hyejung Park, Katharina Waniek, Walter Maetzler, Ingeborg Krägeloh-Mann, Stefanie Lerche, S. Pablo Sardi, Clemens R. Scherzer, Daniela Berg, Kathrin Brockmann, Xuan Mai Petterson, Isabel Wurster, Ann Kathrin Hauser, Douglas Galasko, Brit Mollenhauer, Milan Zimmermann, Benjamin Roeben, Judith Böhringer, Samantha J. Hutten, Thomas Gasser, Bing Wang
Publikováno v:
Movement disorders 36(5), 1216-1228 (2021). doi:10.1002/mds.28472
Background With pathway-specific trials in PD associated with variants in the glucocerebrosidase gene (PDGBA ) under way, we need markers that confirm the impact of genetic variants in patient-derived biofluids in order to allow patient stratificatio
Autor:
Lilian Calderón-Garcidueñas, Partha S. Mukherjee, Katharina Waniek, Max Holzer, Chih-kai Chao, Charles Thompson, Rubén Ruiz-Ramos, Ana Calderón-Garcidueñas, Maricela Franco-Lira, Rafael Reynoso-Robles, Angélica Gónzalez-Maciel, Ingolf Lachmann
Long-term exposure to fine particulate matter (PM2.5) and ozone (O3) above USEPA standards is associated with Alzheimer’s disease (AD) risk. Metropolitan Mexico City (MMC) children exhibit subcortical pretangles in infancy and cortical tau pre-tang
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::36fb44094a4423be7c22b5f27cc56fe9
https://doi.org/10.3233/aiad210040
https://doi.org/10.3233/aiad210040