Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Katharina Wørzner"'
Autor:
Julie Zimmermann, Simon D. van Haren, Joann Diray-Arce, Ignatius Ryan Adriawan, Katharina Wørzner, Ricki T. Krog, Safia Guleed, Tu Hu, Rasmus Mortensen, Jes Dietrich, Sara M. Ø. Solbak, Ofer Levy, Dennis Christensen, Gabriel K. Pedersen
Publikováno v:
npj Vaccines, Vol 8, Iss 1, Pp 1-12 (2023)
Abstract Class-switching to IgG2a/c in mice is a hallmark response to intracellular pathogens. T cells can promote class-switching and the predominant pathway for induction of IgG2a/c antibody responses has been suggested to be via stimulation from T
Externí odkaz:
https://doaj.org/article/b2a5b6ac83564fccb7d1fc8c4727c789
Autor:
Julie Zimmermann, Simon D. van Haren, Joann Diray-Arce, Ignatius Ryan Adriawan, Katharina Wørzner, Ricki T. Krog, Safia Guleed, Tu Hu, Rasmus Mortensen, Jes Dietrich, Sara M. Ø. Solbak, Ofer Levy, Dennis Christensen, Gabriel K. Pedersen
Publikováno v:
npj Vaccines, Vol 9, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/63c1f7f21415417bb945389bc0db3129
Autor:
Katharina Wørzner, Daniel J. Sheward, Signe Tandrup Schmidt, Leo Hanke, Julie Zimmermann, Gerald McInerney, Gunilla B. Karlsson Hedestam, Ben Murrell, Dennis Christensen, Gabriel Kristian Pedersen
Publikováno v:
EBioMedicine, Vol 63, Iss , Pp 103197- (2021)
Background: SARS-CoV-2 has caused a global pandemic, infecting millions of people. A safe, effective vaccine is urgently needed and remains a global health priority. Subunit vaccines are used successfully against other viruses when administered in th
Externí odkaz:
https://doaj.org/article/7ccd452217c5400cb56a66d0bbc2b3c7
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Aluminum salts and squalene based oil-in-water emulsions (SE) are widely used adjuvants in licensed vaccines, yet their mechanisms are not fully known. Here we report that induction of antibody responses displays different kinetics dependent on the a
Externí odkaz:
https://doaj.org/article/a993f0e610a8409a813c23c06481eb37
Autor:
Signe Tandrup Schmidt, Jóhanna Hvannastein, Dennis Christensen, Katharina Wørzner, Ida Rosenkrands, Gabriel K. Pedersen, Camilla Foged
Publikováno v:
European Journal of Pharmaceutics and Biopharmaceutics
Wørzner, K, Hvannastein, J, Tandrup Schmidt, S, Foged, C, Rosenkrands, I, Kristian Pedersen, G & Christensen, D 2021, ' Adsorption of protein antigen to the cationic liposome adjuvant CAF®01 is required for induction of Th1 and Th17 responses but not for antibody induction ', European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, vol. 165, pp. 293-305 . https://doi.org/10.1016/j.ejpb.2021.05.020
Wørzner, K, Hvannastein, J, Tandrup Schmidt, S, Foged, C, Rosenkrands, I, Kristian Pedersen, G & Christensen, D 2021, ' Adsorption of protein antigen to the cationic liposome adjuvant CAF®01 is required for induction of Th1 and Th17 responses but not for antibody induction ', European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, vol. 165, pp. 293-305 . https://doi.org/10.1016/j.ejpb.2021.05.020
Graphical abstract Non-adsorbed antigen administered with the depot-forming, cationic adjuvant formulation (CAF®01) results in low T cell responses, while adsorbed antigen increases T cell responses. Especially Th17 responses benefit from high adsor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27da5fa701ce12b04df543ad10389d55
https://doi.org/10.1016/j.ejpb.2021.05.020
https://doi.org/10.1016/j.ejpb.2021.05.020
Autor:
Camilla Line Olsen, Signe Tandrup Schmidt, Karen Smith Korsholm, Peter Andersen, Henrik Franzyk, Thomas Rades, Katharina Wørzner, Dennis Christensen, Camilla Foged
Publikováno v:
Tandrup Schmidt, S, Line Olsen, C, Franzyk, H, Wørzner, K, Smith Korsholm, K, Rades, T, Andersen, P, Foged, C & Christensen, D 2019, ' Comparison of two different PEGylation strategies for the liposomal adjuvant CAF09 : Towards induction of CTL responses upon subcutaneous vaccine administration ', European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, vol. 140, pp. 29-39 . https://doi.org/10.1016/j.ejpb.2019.04.020
Using subunit vaccines, e.g., based on peptide or protein antigens, to teach the immune system to kill abnormal host cells via induction of cytotoxic T lymphocytes (CTL) is a promising strategy against intracellular infections and cancer. However, cu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f558293a2848105620f65198ec0babdf
https://doi.org/10.1016/j.ejpb.2019.04.020
https://doi.org/10.1016/j.ejpb.2019.04.020
Autor:
Gabriel K. Pedersen, Signe Tandrup Schmidt, Dennis Christensen, Gunilla B. Karlsson Hedestam, Ben Murrel, Julie Zimmermann, Daniel J. Sheward, Leo Hanke, Katharina Wørzner, Gerald M. McInerney
Publikováno v:
EBioMedicine
EBioMedicine, Vol 63, Iss, Pp 103197-(2021)
EBioMedicine, Vol 63, Iss, Pp 103197-(2021)
Background: SARS-CoV-2 has caused a global pandemic, infecting millions of people. A safe, effective vaccine is urgently needed and remains a global health priority. Subunit vaccines are used successfully against other viruses when administered in th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35c3b0e53f795e8b05b0fe760db68d84