Výsledky vyhledávání - "Katharina Thomas"

Akademický článek

Ribonuclease inhibitor 1 emerges as a potential biomarker and modulates inflammation and iron homeostasis in sepsis

Autor: Carolina Neu, Christian Beckers, Nadine Frank, Katharina Thomas, Matthias Bartneck, Tim-Philipp Simon, Jana Mossanen, Kimmo Peters, Tobias Singendonk, Lukas Martin, Gernot Marx, Sandra Kraemer, Elisabeth Zechendorf

Publikováno v: Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)

Abstract Sepsis, marked by organ dysfunction, necessitates reliable biomarkers. Ribonuclease inhibitor 1 (RNH1), a ribonuclease (RNase) inhibitor, emerged as a potential biomarker for acute kidney injury and mortality in thoracoabdominal aortic aneur

Externí odkaz: https://doaj.org/article/74d1435f19a343e8bdda8367b314c237

Zobrazit plný text záznamu

Plný text ve formátu HTML

Akademický článek

P-selectin-dependent leukocyte adhesion is governed by endolysosomal two-pore channel 2

Autor: Jonas Goretzko, Inga Pauels, Nicole Heitzig, Katharina Thomas, Marina Kardell, Johannes Naß, Einar Kleinhans Krogsaeter, Sebastian Schloer, Barbara Spix, Anna Lívia Linard Matos, Charlotte Leser, Tristan Wegner, Frank Glorius, Franz Bracher, Volker Gerke, Jan Rossaint, Christian Grimm, Ursula Rescher

Publikováno v: Cell Reports, Vol 42, Iss 12, Pp 113501- (2023)

Summary: Upon proinflammatory challenges, endothelial cell surface presentation of the leukocyte receptor P-selectin, together with the stabilizing co-factor CD63, is needed for leukocyte capture and is mediated via demand-driven exocytosis from the

Externí odkaz: https://doaj.org/article/743e166b584b4ba9a9ee505a123e92b3

Zobrazit plný text záznamu

Akademický článek

Glutamine prevents acute kidney injury by modulating oxidative stress and apoptosis in tubular epithelial cells

Publikováno v: JCI Insight, Vol 7, Iss 21 (2022)

Acute kidney injury (AKI) represents a common complication in critically ill patients that is associated with increased morbidity and mortality. In a murine AKI model induced by ischemia/reperfusion injury (IRI), we show that glutamine significantly

Externí odkaz: https://doaj.org/article/30ea337b9c5d4c7ea8eab77560c841db

Zobrazit plný text záznamu

Akademický článek

Remote ischemic preconditioning causes transient cell cycle arrest and renal protection by a NF-κB–dependent Sema5B pathway

Autor: Jan Rossaint, Melanie Meersch, Katharina Thomas, Sina Mersmann, Martin Lehmann, Jennifer Skupski, Tobias Tekath, Peter Rosenberger, John A. Kellum, Hermann Pavenstädt, Alexander Zarbock

Publikováno v: JCI Insight, Vol 7, Iss 14 (2022)

Acute kidney injury increases morbidity and mortality, and previous studies have shown that remote ischemic preconditioning (RIPC) reduces the risk of acute kidney injury after cardiac surgery. RIPC increases urinary high mobility group box protein-1

Externí odkaz: https://doaj.org/article/5b4605dd23ba458f874aefa40181f27b

Zobrazit plný text záznamu

Akademický článek

The Pathogenesis of Ischemia-Reperfusion Induced Acute Kidney Injury Depends on Renal Neutrophil Recruitment Whereas Sepsis-Induced AKI Does Not

Autor: Zhenhan Li, Nadine Ludwig, Katharina Thomas, Sina Mersmann, Martin Lehmann, Dietmar Vestweber, Jean-Francois Pittet, Hernando Gomez, John A. Kellum, Jan Rossaint, Alexander Zarbock

Publikováno v: Frontiers in Immunology, Vol 13 (2022)

Acute kidney injury (AKI) may be induced by different causes, including renal ischemia-reperfusion injury and sepsis, which represent the most common reasons for AKI in hospitalized patients. AKI is defined by reduced urine production and/or increase

Externí odkaz: https://doaj.org/article/643a80cce42f42a292654931518c71c2

Zobrazit plný text záznamu

Akademický článek

Development of a Novel mcr-6 to mcr-9 Multiplex PCR and Assessment of mcr-1 to mcr-9 Occurrence in Colistin-Resistant Salmonella enterica Isolates From Environment, Feed, Animals and Food (2011–2018) in Germany

Autor: Maria Borowiak, Beatrice Baumann, Jennie Fischer, Katharina Thomas, Carlus Deneke, Jens Andre Hammerl, Istvan Szabo, Burkhard Malorny

Publikováno v: Frontiers in Microbiology, Vol 11 (2020)

The polymyxin antibiotic colistin has been used in decades for treatment and prevention of infectious diseases in livestock. Nowadays, it is even considered as last-line treatment option for severe human infections caused by multidrug- and carbapenem

Externí odkaz: https://doaj.org/article/2708ea43d32e4ebfa9006174ce8d3dc8

Zobrazit plný text záznamu

Akademický článek

Prevalence of mcr-1 in E. coli from Livestock and Food in Germany, 2010-2015.

Autor: Alexandra Irrgang, Nicole Roschanski, Bernd-Alois Tenhagen, Mirjam Grobbel, Tanja Skladnikiewicz-Ziemer, Katharina Thomas, Uwe Roesler, Annemarie Käsbohrer

Publikováno v: PLoS ONE, Vol 11, Iss 7, p e0159863 (2016)

Since the first description of a plasmid-mediated colistin resistance gene (mcr-1) in November 2015 multiple reports of mcr-1 positive isolates indicate a worldwide spread of this newly discovered resistance gene in Enterobacteriaceae. Although the o

Externí odkaz: https://doaj.org/article/e815c60fe8164f2d970b25291075498f

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání