Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Katharina Schimmel"'
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2022)
Myocardial fibrosis is a remodeling process of the extracellular matrix (ECM) following cardiac stress. “Replacement fibrosis” is a term used to describe wound healing in the acute phase of an injury, such as myocardial infarction. In striking co
Externí odkaz:
https://doaj.org/article/48098b7dd40a44b087fe2662de6579ad
Autor:
Md Khadem Ali, Xuefei Tian, Lan Zhao, Katharina Schimmel, Christopher J. Rhodes, Martin R. Wilkins, Mark R. Nicolls, Edda F. Spiekerkoetter
Publikováno v:
Cells, Vol 12, Iss 2, p 316 (2023)
Bone morphogenic protein receptor 2 (BMPR2) expression and signaling are impaired in pulmonary arterial hypertension (PAH). How BMPR2 signaling is decreased in PAH is poorly understood. Protein tyrosine phosphatases (PTPs) play important roles in vas
Externí odkaz:
https://doaj.org/article/39d052282cc64d45b9ac50bfe066e383
Autor:
Franziska Kenneweg, Claudia Bang, Ke Xiao, Chantal M. Boulanger, Xavier Loyer, Stephane Mazlan, Blanche Schroen, Steffie Hermans-Beijnsberger, Ariana Foinquinos, Marc N. Hirt, Thomas Eschenhagen, Sandra Funcke, Stevan Stojanovic, Celina Genschel, Katharina Schimmel, Annette Just, Angelika Pfanne, Kristian Scherf, Susann Dehmel, Stella M. Raemon-Buettner, Jan Fiedler, Thomas Thum
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 18, Iss , Pp 363-374 (2019)
Long non-coding RNAs (lncRNAs) have potential as novel therapeutic targets in cardiovascular diseases, but detailed information about the intercellular lncRNA shuttling mechanisms in the heart is lacking. Here, we report an important novel crosstalk
Externí odkaz:
https://doaj.org/article/082462a5ca7046e4a3a1e853a2b8ca0e
Autor:
Anselm A Derda, Angelika Pfanne, Christian Bär, Katharina Schimmel, Peter J Kennel, Ke Xiao, P Christian Schulze, Johann Bauersachs, Thomas Thum
Publikováno v:
PLoS ONE, Vol 13, Iss 10, p e0204235 (2018)
INTRODUCTION:Amyloidosis is caused by dysregulation of protein folding resulting in systemic or organ specific amyloid aggregation. When affecting the heart, amyloidosis can cause severe heart failure, which is associated with a high morbidity and mo
Externí odkaz:
https://doaj.org/article/f4eae2bd83744d61ac12d5edc73e22b7
Autor:
Lan Zhao, Christine M. Cunningham, Adam M. Andruska, Katharina Schimmel, Md Khadem Ali, Dongeon Kim, Shenbiao Gu, Jason L. Chang, Edda Spiekerkoetter, Mark R. Nicolls
Publikováno v:
bioRxiv
The laboratory rat emerges as a useful tool for studying the interaction between the host and its microbiome. To advance principles relevant to the human microbiome, we systematically investigated and defined a multi-tissue full lifespan microbial bi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1250e28580a2a228e9ea771f38aca235
https://doi.org/10.1101/2023.05.19.541527
https://doi.org/10.1101/2023.05.19.541527
Autor:
Md Khadem Ali, Yu Liu, Katharina Schimmel, Nicholas H. Juul, Courtney A. Stockman, Joseph C. Wu, Edda F. Spiekerkoetter
Hereditary Hemorrhagic Telangiectasia (HHT) is an autosomal dominant disease that causes arteriovenous vascular malformations (AVMs) in different organs, including the lung. Three genes, ENG (endoglin), ACVRL1 (ALK1) and SMAD4, all members of the TGF
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2ba28dfc95a70c5748a7ce30d46cfccd
https://doi.org/10.1101/2022.11.25.517570
https://doi.org/10.1101/2022.11.25.517570
Autor:
Kavya Shah, Isabel Morgado, Kevin M. Alexander, Alessandro Evangelisti, Shaurya Joshi, Sudeshna Fisch, Katharina Schimmel, Ronglih Liao
Publikováno v:
Journal of Visualized Experiments.
The zebrafish (Danio rerio) has become a very popular model organism in cardiovascular research, including human cardiac diseases, largely due to its embryonic transparency, genetic tractability, and amenity to rapid, high-throughput studies. However
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::120b8b3be3cb65d6f0dd3de5df277002
https://doi.org/10.3791/60976-v
https://doi.org/10.3791/60976-v
Autor:
Soeun Ngoy, Felix Kleemiss, Heike Janssen-Peters, Ariana Foinquinos, Angelika Pfanne, Kristian Scherf, Javier Beaumont, Kevin M. Alexander, Arantxa González, Lisa Hobuß, Begoña López, Seema Dangwal, Sudeshna Fisch, Sabine Samolovac, Franziska Kenneweg, Christina Brandenberger, Maria-Teresa Piccoli, Gorka San José, Susana Ravassa, Katharina Schimmel, Lea Grote-Levi, Javier Díez, Mira Jung, Nicola Wilck, Jan Hinrich Braesen, Janet Remke, Karina Zimmer, Robert Geffers, Jan Fiedler, Annette Just, Quoc-Tuan Do, Ke Xiao, Thomas Thum, Katharina Bock, Laura Santer, Sandor Batkai, Volkhard Kaever, Julia Leonardy, Ronglih Liao, Dominik N. Müller, Heike Bähre, Christian Bär, Bradley M. Wertheim, Fabian Philipp Kreutzer, Jessica Schmitz
Publikováno v:
Circulation
United States
United States
Supplemental Digital Content is available in the text.
Background: Myocardial fibrosis is a hallmark of cardiac remodeling and functionally involved in heart failure development, a leading cause of deaths worldwide. Clinically, no therapeutic st
Background: Myocardial fibrosis is a hallmark of cardiac remodeling and functionally involved in heart failure development, a leading cause of deaths worldwide. Clinically, no therapeutic st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f36956ed360e6ca8cb14045cff81fbe
https://hdl.handle.net/10033/622209
https://hdl.handle.net/10033/622209
Autor:
Khadem Ali, Serena Y. Tan, David A. Stevenson, Gary K. Steinberg, Huy M. Do, Edda Spiekerkoetter, Katharina Schimmel, Joyce M.C. Teng
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 9037, p 9037 (2021)
International Journal of Molecular Sciences
International Journal of Molecular Sciences
Arteriovenous malformations are a vascular anomaly typically present at birth, characterized by an abnormal connection between an artery and a vein (bypassing the capillaries). These high flow lesions can vary in size and location. Therapeutic approa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15856077e4b5610cf07348ee426d0fe9
https://doi.org/10.3390/ijms22169037
https://doi.org/10.3390/ijms22169037
Autor:
Katharina Schimmel, Ronald M. Witteles, Michaela Liedtke, Cheng-Yu Tsai, Kevin M. Alexander, Seema Dangwal, Isabel Morgado, Ronglih Liao, Jennifer E. Ward, Alokkumar Jha, Dian J Lee
Publikováno v:
Circulation Research. 125
Amyloid light chain (AL) amyloidosis results from tissue deposition of clonal light chains, most commonly produced by clonal plasma cells. AL amyloidosis is closely associated with multiple myeloma (MM), another disease which arises from clonal plasm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c720a3190ea21fbe8e7ac2ebb06a393e
https://doi.org/10.1161/res.125.suppl_1.750
https://doi.org/10.1161/res.125.suppl_1.750