Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Katharina Sahm"'
Autor:
Frank A. Giordano, Julian P. Layer, Sonia Leonardelli, Lea L. Friker, Roberta Turiello, Dillon Corvino, Thomas Zeyen, Christina Schaub, Wolf Müller, Elena Sperk, Leonard Christopher Schmeel, Katharina Sahm, Christoph Oster, Sied Kebir, Peter Hambsch, Torsten Pietsch, Sotirios Bisdas, Michael Platten, Martin Glas, Clemens Seidel, Ulrich Herrlinger, Michael Hölzel
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract The chemokine CXCL12 promotes glioblastoma (GBM) recurrence after radiotherapy (RT) by facilitating vasculogenesis. Here we report outcomes of the dose-escalation part of GLORIA (NCT04121455), a phase I/II trial combining RT and the CXCL12-n
Externí odkaz:
https://doaj.org/article/a461b70c215e421cabb2b9a14f5dfb4b
Autor:
Katharina Sahm, Tobias Kessler, Philipp Eisele, Miriam Ratliff, Elena Sperk, Laila König, Michael O. Breckwoldt, Corinna Seliger, Iris Mildenberger, Daniel Schrimpf, Christel Herold-Mende, Pia S. Zeiner, Ghazaleh Tabatabai, Sven G. Meuth, David Capper, Martin Bendszus, Andreas von Deimling, Wolfgang Wick, Felix Sahm, Michael Platten
Publikováno v:
Communications Medicine, Vol 3, Iss 1, Pp 1-9 (2023)
Abstract Background Concurrent malignant brain tumors in patients with multiple sclerosis (MS) constitute a rare but paradigmatic phenomenon for studying neuroimmunological mechanisms from both molecular and clinical perspectives. Methods A multicent
Externí odkaz:
https://doaj.org/article/85b83cf8178849efa2c0227482eb36de
Autor:
Niklas Grassl, Katharina Sahm, Heike Süße, Isabel Poschke, Lukas Bunse, Theresa Bunse, Tamara Boschert, Iris Mildenberger, Anne-Kathleen Rupp, Max Philipp Ewinger, Lisa-Marie Lanz, Monika Denk, Ghazaleh Tabatabai, Michael W. Ronellenfitsch, Ulrich Herrlinger, Martin Glas, Dietmar Krex, Peter Vajkoczy, Antje Wick, Inga Harting, Felix Sahm, Andreas von Deimling, Martin Bendszus, Wolfgang Wick, Michael Platten
Publikováno v:
Neurological Research and Practice, Vol 5, Iss 1, Pp 1-6 (2023)
Abstract Introduction Diffuse midline gliomas (DMG) are universally lethal central nervous system tumors that carry almost unanimously the clonal driver mutation histone-3 K27M (H3K27M). The single amino acid substitution of lysine to methionine harb
Externí odkaz:
https://doaj.org/article/968882c501c548889b7af8e6c08a2e21
Autor:
Isabel Poschke, Michael Platten, Edward Green, Katharina Lindner, Tamara Boschert, Taga Lerner, Kristina Kromer, Iris Mildenberger, Gordon Haltenhof, Katharina Sahm, John Lindner
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/849c54a076e343459d6c48f79f501a2f
Autor:
Michael Platten, Julius Michel, Khwab Sanghvi, Kristine Jähne, Michael Breckwoldt, Katharina Sahm, Nirmeen Elmadany, Jana Sonner, Svetlana Ovchinnikova, Isabelle Bernhardt, Xin-Wen Zhang, Ankita Sati, Simon Anders
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/24f42edede9947549c87d4b5bd34c655
Autor:
Rienk Offringa, Ralf Lesche, Iris Oezen, Michael Platten, Daniel Baumann, Christiane A Opitz, Ahmed Sadik, Catherine Olesch, Frederik Cichon, Norbert Schmees, Ulrike Roehn, Florian Prinz, Detlef Stoeckigt, Katharina Sahm, Nirmeen Elmadany, Christina Kober, Julian Roewe, Lars Roese, Benjamin Bader, Mátyás Gorjánácz, Helge Gottfried Roider, Gabriele Leder, Horst Irlbacher, Julien Lefranc, Mine Oezcan-Wahlbrink, Ankita Sati Batra, Rafael Carretero, Hilmar Weinmann, Ingo V Hartung, Bertolt Kreft, Ilona Gutcher
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss 11 (2023)
Background The metabolism of tryptophan to kynurenines (KYN) by indoleamine-2,3-dioxygenase or tryptophan-2,3-dioxygenase is a key pathway of constitutive and adaptive tumor immune resistance. The immunosuppressive effects of KYN in the tumor microen
Externí odkaz:
https://doaj.org/article/bc1e59d7b2b148a6869f255df5b9d454
Autor:
Tareq M. Haedenkamp, Michael F. Leitzmann, Ralf A. Linker, Christoph Meier, Claudia Becker, Susan Jick, Katharina Sahm, Michael Platten, Peter Hau, Corinna Seliger
Publikováno v:
Cancer Medicine, Vol 9, Iss 3, Pp 1263-1275 (2020)
Abstract Effectors from the immune system can modulate the course and possibly the early development of gliomas. We, therefore, hypothesized that autoimmune diseases associated with increased immune‐surveillance may also modulate the risk of human
Externí odkaz:
https://doaj.org/article/f19ed228d7bf43808c7829f53fa14f5d
Autor:
Xin-Wen Zhang, Katrin Huck, Kristine Jähne, Frederik Cichon, Jana K. Sonner, Friederike Ufer, Simone Bauer, Marcel Seungsu Woo, Ed Green, Kevin Lu, Michael Kilian, Manuel A. Friese, Michael Platten, Katharina Sahm
Publikováno v:
OncoImmunology, Vol 10, Iss 1 (2021)
Dendritic cell (DC) vaccination has proven to be an effective and safe adjuvant for cancer immunotherapies. As the presence of DCs within the tumor microenvironment promotes adaptive antitumor immunity, enhancement of DC migration toward the tumor mi
Externí odkaz:
https://doaj.org/article/120b4e58a8d94f16b42d63ed0b3633e5
Autor:
Katharina Sahm, Tobias Kessler, Philipp Eisele, Miriam Ratliff, Elena Sperk, Laila König, Michael O. Breckwoldt, Corinna Seliger, Iris Mildenberger, Daniel Schrimpf, Christel Herold-Mende, Pia S. Zeiner, Ghazaleh Tabatabai, Sven G. Meuth, David Capper, Martin Bendszus, Andreas von Deimling, Wolfgang Wick, Felix Sahm, Michael Platten
BackgroundConcurrent malignant brain tumors in patients with multiple sclerosis (MS) constitute a rare but paradigmatic phenomenon for studying neuroimmunological mechanisms from both molecular and clinical perspectives.MethodsA multicenter cohort of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ed862924881e61cd479b0d8270d0d980
https://doi.org/10.1101/2022.07.01.22277047
https://doi.org/10.1101/2022.07.01.22277047
Autor:
Frank Anton Giordano, Julian Philipp Layer, Sonia Leonardelli, Lea Lydia Friker, Clemens Seidel, Christina Schaub, Roberta Turiello, Elena Sperk, Franziska Grau, Daniel Paech, Barbara Link, Wolf Mueller, Ghazaleh Tabatabai, Katharina Sahm, Sied Kebir, Torsten Pietsch, Martin Glas, Sotiros Bisdas, Ulrich Herrlinger, Michael Hölzel
2050 Background: Pre-clinical studies consistently demonstrate that inhibition of the CXCL12/CXCR4/CXCR7 axis abrogates recruitment of pro-vasculogenic bone marrow-derived cells after radiotherapy (RT) of glioblastoma (GBM) and promotes T cell exclus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3c3acd320b7be115008633c54cafa12