Characterization of a SARS-CoV-2 Omicron BA.5 direct-contact transmission model in hamsters

Autor: Kim Handrejk, Katharina S. Schmitz, Edwin J. B. Veldhuis Kroeze, Laura L. A. van Dijk, Peter van Run, Bart Haagmans, Anne Moscona, Matteo Porotto, Rik L. de Swart, Rory D. de Vries, Melanie Rissmann

Publikováno v: npj Viruses, Vol 2, Iss 1, Pp 1-10 (2024)

Abstract As SARS-CoV-2 continues to evolve antigenically to escape vaccine- or infection-induced immunity, suitable animal models are needed to study novel interventions against viral variants. Syrian hamsters are often used because of their high sus

Externí odkaz: https://doaj.org/article/79afa63faedd454ab5087fbab9ac575d

Infection of ferrets with wild type-based recombinant canine distemper virus overwhelms the immune system and causes fatal systemic disease

Autor: Brigitta M. Laksono, Dagmar Roelofs, Anouskha D. Comvalius, Katharina S. Schmitz, Laurine C. Rijsbergen, Daryl Geers, Sham Nambulli, Peter van Run, W. Paul Duprex, Judith M. A. van den Brand, Rory D. de Vries, Rik L. de Swart

Publikováno v: mSphere, Vol 8, Iss 4 (2023)

ABSTRACT Canine distemper virus (CDV) causes systemic infection resulting in severe and often fatal disease in a large spectrum of animal host species. The virus is closely related to measles virus and targets myeloid, lymphoid, and epithelial cells,

Externí odkaz: https://doaj.org/article/4bda23daf9864f099be972878bb93daa

Ad26.COV2.S priming provided a solid immunological base for mRNA-based COVID-19 booster vaccination

Autor: Daryl Geers, Roos S.G. Sablerolles, Debbie van Baarle, Neeltje A. Kootstra, Wim J.R. Rietdijk, Katharina S. Schmitz, Lennert Gommers, Susanne Bogers, Nella J. Nieuwkoop, Laura L.A. van Dijk, Eva van Haren, Melvin Lafeber, Virgil A.S.H. Dalm, Abraham Goorhuis, Douwe F. Postma, Leo G. Visser, Anke L.W. Huckriede, Alessandro Sette, Alba Grifoni, Rik L. de Swart, Marion P.G. Koopmans, P. Hugo M. van der Kuy, Corine H. GeurtsvanKessel, Rory D. de Vries

Publikováno v: iScience, Vol 26, Iss 1, Pp 105753- (2023)

Summary: The emergence of novel SARS-CoV-2 variants led to the recommendation of booster vaccinations after Ad26.COV2.S priming. It was previously shown that heterologous booster vaccination induces high antibody levels, but how heterologous boosters

Externí odkaz: https://doaj.org/article/7025f88ac3c142ad82c99ff25f52018b

Modeling Infection and Tropism of Human Parainfluenza Virus Type 3 in Ferrets

Autor: Laurine C. Rijsbergen, Katharina S. Schmitz, Lineke Begeman, Jennifer Drew-Bear, Lennert Gommers, Mart M. Lamers, Alexander L. Greninger, Bart L. Haagmans, Matteo Porotto, Rik L. de Swart, Anne Moscona, Rory D. de Vries

Publikováno v: mBio, Vol 13, Iss 1 (2022)

ABSTRACT Human parainfluenza virus type 3 (HPIV-3) is a significant cause of lower respiratory tract infections, with the most severe disease in young infants, immunocompromised individuals, and the elderly. HPIV-3 infections are currently untreatabl

Externí odkaz: https://doaj.org/article/59de9795e93d42eb9482516823493a2b

Pathogenesis of wild-type- and vaccine-based recombinant peste des petits ruminants virus (PPRV) expressing EGFP in experimentally infected domestic goats

Autor: Katharina S. Schmitz, Phaedra L. Eblé, René G. P. van Gennip, Mieke A. Maris-Veldhuis, Rory D. de Vries, Lucien J. M. van Keulen, Rik L. de Swart, Piet A. van Rijn

Publikováno v: The Journal of general virology, 104(2)
The Journal of general virology, 104(2). Microbiology Society
The Journal of general virology 104 (2023) 2

Peste des petits ruminants virus (PPRV) is a highly contagious morbillivirus related to measles and canine distemper virus, mostly affecting small ruminants. The corresponding PPR disease has a high clinical impact in goats and is characterized by fe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3349a9395685a792da34b50dec297419
https://doi.org/10.1099/jgv.0.001828