Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Katharina S, Götze"'
Autor:
Paolo Mazzeo, Christina Ganster, John Wiedenhöft, Katayoon Shirneshan, Katharina Rittscher, Elzbieta B. Brzuszkiewicz, Doris Steinemann, Maximilian Schieck, Catharina Müller‐Thomas, Hannes Treiber, Friederike Braulke, Ulrich Germing, Katja Sockel, Ekaterina Balaian, Julie Schanz, Uwe Platzbecker, Katharina S. Götze, Detlef Haase
Publikováno v:
HemaSphere, Vol 8, Iss 9, Pp n/a-n/a (2024)
Abstract The acquisition of subsequent genetic lesions (clonal evolution, CE) and/or the expansion of existing clones (CEXP) contributes to clonal dynamics (CD) in myelodysplastic syndromes (MDS). Although CD plays an important role in high‐risk pa
Externí odkaz:
https://doaj.org/article/9f9765fadd3f4a46b49121560b7c1069
Platelet mass cytometry reveals dysregulation of prothrombotic pathways in essential thrombocythemia
Autor:
Veronika Dill, Kilian Kirmes, Jiaying Han, Melissa Klug, Marc Rosenbaum, Giacomo Viggiani, Moritz von Scheidt, Markus List, Peter Herhaus, Jürgen Ruland, Florian Bassermann, Karl-Ludwig Laugwitz, Katharina S. Götze, Philipp J. Jost, Stefanie Jilg, Conor J. Bloxham, Philip W.J. Raake, Isabell Bernlochner, Dario Bongiovanni
Publikováno v:
Platelets, Vol 35, Iss 1 (2024)
Thromboembolic events are common in patients with essential thrombocythemia (ET). However, the pathophysiological mechanisms underlying the increased thrombotic risk remain to be determined. Here, we perform the first phenotypical characterization of
Externí odkaz:
https://doaj.org/article/6b03b9ff955e40ae9ff5ee319c518d34
Autor:
Krischan Braitsch, Samuel D. Jeske, Jacob Stroh, Maike Hefter, Louise Platen, Quirin Bachmann, Lutz Renders, Ulrike Protzer, Katharina S. Götze, Peter Herhaus, Mareike Verbeek, Christoph D. Spinner, Florian Bassermann, Marion Högner, Bernhard Haller, Jochen Schneider, Michael Heider
Publikováno v:
Vaccines, Vol 12, Iss 8, p 871 (2024)
Patients with hematologic malignancies still face a significant risk of severe coronavirus disease 2019 (COVID-19). The severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2)-neutralizing monoclonal antibody combination tixagevimab/cilgavi
Externí odkaz:
https://doaj.org/article/4b7f987275f945a7ba77c83efab64ece
Autor:
Jennifer Rivière, Jennifer Hock, Michèle C. Buck, Judith S. Hecker, Katharina S. Götze, Mark van der Garde
Publikováno v:
Stem Cell Research & Therapy, Vol 14, Iss 1, Pp 1-5 (2023)
Abstract Bone marrow samples from discarded femoral heads are often used as healthy controls in studies investigating the in vitro characteristics of cells from patients with hematologic malignancies. Since patient samples are usually derived from il
Externí odkaz:
https://doaj.org/article/48a4a791f90543699bfb5f5fb099ad02
Autor:
Frank G Rücker, Lars Bullinger, Sibylle Cocciardi, Sabrina Skambraks, Tamara J Luck, Daniela Weber, Isabelle Schneider, Andrea Corbacioglu, Verena I Gaidzik, Ekaterina Jahn, Nikolaus Jahn, Silke Kapp-Schwoerer, Anika Schrade, Frauke Theis, Walter Fiedler, Helmut R Salih, Gerald Wulf, Hans Salwender, Thomas Schroeder, Katharina S Götze, Thomas Kindler, Michael Lübbert, Richard F Schlenk, Felicitas Thol, Michael Heuser, Arnold Ganser, Hartmut Döhner, Konstanze Döhner
Publikováno v:
HemaSphere, Vol 7, p e29390a8 (2023)
Externí odkaz:
https://doaj.org/article/eae6758e5a2d4ab493e1f62d7fc2e7eb
Autor:
Michèle C. Buck, Lisa Bast, Judith S. Hecker, Jennifer Rivière, Maja Rothenberg-Thurley, Luisa Vogel, Dantong Wang, Immanuel Andrä, Fabian J. Theis, Florian Bassermann, Klaus H. Metzeler, Robert A.J. Oostendorp, Carsten Marr, Katharina S. Götze
Publikováno v:
iScience, Vol 26, Iss 8, Pp 107328- (2023)
Summary: Clonal hematopoiesis of indeterminate potential (CHIP) describes the age-related acquisition of somatic mutations in hematopoietic stem/progenitor cells (HSPC) leading to clonal blood cell expansion. Although CHIP mutations drive myeloid mal
Externí odkaz:
https://doaj.org/article/a281b751b3e543528abcca4b0e8c1c42
Autor:
Maik Herbig, Angela Jacobi, Manja Wobus, Heike Weidner, Anna Mies, Martin Kräter, Oliver Otto, Christian Thiede, Marie‑Theresa Weickert, Katharina S. Götze, Martina Rauner, Lorenz C. Hofbauer, Martin Bornhäuser, Jochen Guck, Marius Ader, Uwe Platzbecker, Ekaterina Balaian
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-8 (2022)
Abstract Diagnosis of myelodysplastic syndrome (MDS) mainly relies on a manual assessment of the peripheral blood and bone marrow cell morphology. The WHO guidelines suggest a visual screening of 200 to 500 cells which inevitably turns the assessor b
Externí odkaz:
https://doaj.org/article/47750a67f89b4072ae8b903f4aa9907e
Autor:
Christoph Rummelt, Olga Grishina, Claudia Schmoor, Martina Crysandt, Michael Heuser, Katharina S. Götze, Richard F. Schlenk, Konstanze Döhner, Helmut R. Salih, Gerhard Heil, Carsten Müller-Tidow, Wolfram Brugger, Andrea Kündgen, Maike de Wit, Aristoteles Giagounidis, Sebastian Scholl, Andreas Neubauer, Jürgen Krauter, Gesine Bug, Haifa Kathrin Al-Ali, Ralph Wäsch, Heiko Becker, Annette M. May, Justus Duyster, Björn Hackanson, Arnold Ganser, Hartmut Döhner, Michael Lübbert
Publikováno v:
Haematologica, Vol 108, Iss 8 (2023)
Externí odkaz:
https://doaj.org/article/3448ad0c720c4bd583057eb97a440fb5
Autor:
Christina Rautenberg, Friedrich Stölzel, Christoph Röllig, Matthias Stelljes, Verena Gaidzik, Michael Lauseker, Oliver Kriege, Mareike Verbeek, Julia Marie Unglaub, Felicitas Thol, Stefan W. Krause, Mathias Hänel, Charlotte Neuerburg, Vladan Vucinic, Christian-Friedrich Jehn, Julia Severmann, Maxi Wass, Lars Fransecky, Jens Chemnitz, Udo Holtick, Kerstin Schäfer-Eckart, Josephine Schröder, Sabrina Kraus, William Krüger, Ulrich Kaiser, Sebastian Scholl, Kathrin Koch, Lea Henning, Guido Kobbe, Rainer Haas, Nael Alakel, Maximilian-Alexander Röhnert, Katja Sockel, Maher Hanoun, Uwe Platzbecker, Tobias A. W. Holderried, Anke Morgner, Michael Heuser, Tim Sauer, Katharina S. Götze, Eva Wagner-Drouet, Konstanze Döhner, Hartmut Döhner, Christoph Schliemann, Johannes Schetelig, Martin Bornhäuser, Ulrich Germing, Thomas Schroeder, Jan Moritz Middeke
Publikováno v:
Blood Cancer Journal, Vol 11, Iss 10, Pp 1-8 (2021)
Abstract To investigate the efficacy and toxicities of CPX-351 outside a clinical trial, we analyzed 188 patients (median age 65 years, range 26–80) treated for therapy-related acute myeloid leukemia (t-AML, 29%) or AML with myelodysplasia-related
Externí odkaz:
https://doaj.org/article/227f98dd88a74dfd8f202c1342f289b3
Autor:
Jeannine Diesch, Marguerite-Marie Le Pannérer, René Winkler, Raquel Casquero, Matthias Muhar, Mark van der Garde, Michael Maher, Carolina Martínez Herráez, Joan J. Bech-Serra, Michaela Fellner, Philipp Rathert, Nigel Brooks, Lurdes Zamora, Antonio Gentilella, Carolina de la Torre, Johannes Zuber, Katharina S. Götze, Marcus Buschbeck
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Azacitidine (AZA) treatment is used for patients with myelodysplasias that cannot undergo bone marrow transplantation; however, AZA treatment is only partially effective. Here the authors show synergy of AZA with compounds inhibiting the chromatin re
Externí odkaz:
https://doaj.org/article/d0619bde27374a0bbc9ce933934d9f91