Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Katharina Ritter"'
Publikováno v:
BMC Neuroscience, Vol 25, Iss 1, Pp 1-14 (2024)
Abstract TBI is a leading cause of death and disability in young people and older adults worldwide. There is no gold standard treatment for TBI besides surgical interventions and symptomatic relief. Post-injury infections, such as lower respiratory t
Externí odkaz:
https://doaj.org/article/29041a40f0014eff812b4e6caddb9c92
Autor:
Katharina Ritter, René Rissel, Miriam Renz, Alexander Ziebart, Michael K. E. Schäfer, Jens Kamuf
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 18, p 10117 (2024)
Lung injury caused by respiratory infection is a major cause of hospitalization and mortality and a leading origin of sepsis. Sepsis-associated encephalopathy and delirium are frequent complications in patients with severe lung injury, yet the pathog
Externí odkaz:
https://doaj.org/article/e7a9536cea3c4a04b912433f00ca8305
Publikováno v:
Biomedicines, Vol 12, Iss 7, p 1399 (2024)
Traumatic brain injury (TBI) and long bone fractures are a common injury pattern in polytrauma patients and modulate each other’s healing process. As only a limited number of studies have investigated both traumatic sites, we tested the hypothesis
Externí odkaz:
https://doaj.org/article/edd25dba69344802b711582fda1cde41
Autor:
Tobias J. Krämer, Florian Pickart, Bruno Pöttker, Christina Gölz, Axel Neulen, Tobias Pantel, Hermann Goetz, Katharina Ritter, Michael K. E. Schäfer, Serge C. Thal
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract Traumatic brain injury (TBI) causes the release of danger-associated molecular patterns (DAMP) from damaged or dead cells, which contribute to secondary brain damage after TBI. Cell-free DNA (cfDNA) is a DAMP known to cause disruption of the
Externí odkaz:
https://doaj.org/article/86feabec15364ca8b03bfda43c74c694
Autor:
Regina Hummel, Erika Dorochow, Sonja Zander, Katharina Ritter, Lisa Hahnefeld, Robert Gurke, Irmgard Tegeder, Michael K. E. Schäfer
Publikováno v:
Cells, Vol 13, Iss 9, p 734 (2024)
The histone deacetylase inhibitor (HDACi) valproic acid (VPA) has neuroprotective and anti-inflammatory effects in experimental traumatic brain injury (TBI), which have been partially attributed to the epigenetic disinhibition of the transcription re
Externí odkaz:
https://doaj.org/article/53424d87a10a4d8da9740ff99c59f0c6
Autor:
René Rissel, Miriam Renz, Katja Mohnke, Julian Riedel, Katharina Ritter, Alexander Ziebart, Robert Ruemmler, Erik K. Hartmann, Jens Kamuf
Publikováno v:
Intensive Care Medicine Experimental, Vol 10, Iss 1, Pp 1-13 (2022)
Abstract Background Acute respiratory distress syndrome (ARDS) is a common disease in intensive care medicine. Despite intensive research, mortality rates are high, not even in COVID-19 ARDS. Thereby, pigs offer some advantages to study the character
Externí odkaz:
https://doaj.org/article/7f38dda4ddf5438886b2a526444608a4
Autor:
Tobias J. Krämer, Per Hübener, Bruno Pöttker, Christina Gölz, Axel Neulen, Tobias Pantel, Hermann Goetz, Katharina Ritter, Michael K. E. Schäfer, Serge C. Thal
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract Traumatic brain injury (TBI) involves primary mechanical damage and delayed secondary damage caused by vascular dysfunction and neuroinflammation. Intracellular components released into the parenchyma and systemic circulation, termed danger-
Externí odkaz:
https://doaj.org/article/0ce2da96cf5846cca14e90f9009e0a54
Autor:
Katharina Ritter, Kirsten Jung, Christopher Dolderer, Dominik Appel, Christine C. Oswald, Ulrike Ritz, Michael K. E. Schäfer
Publikováno v:
Mediators of Inflammation, Vol 2021 (2021)
Traumatic brain injury (TBI) represents a major cause of death and disability in early adulthood. Concomitant extracranial injury such as long bone fracture was reported to exacerbate TBI pathology. However, early reciprocal effects and mechanisms ha
Externí odkaz:
https://doaj.org/article/0792f174dc904e1ebae2333a7ec6b63c
Autor:
Yong Wang, Isa Wernersbach, Jenny Strehle, Shuailong Li, Dominik Appel, Matthias Klein, Katharina Ritter, Regina Hummel, Irmgard Tegeder, Michael K.E. Schäfer
Publikováno v:
Brain, Behavior, and Immunity. 106:49-66
There is a need for early therapeutic interventions after traumatic brain injury (TBI) to prevent neurodegeneration. Microglia/macrophage (M/M) depletion and repopulation after treatment with colony stimulating factor 1 receptor (CSF1R) inhibitors re