Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Katharina Overlack"'
Autor:
Amal Alex, Valentina Piano, Soumitra Polley, Marchel Stuiver, Stephanie Voss, Giuseppe Ciossani, Katharina Overlack, Beate Voss, Sabine Wohlgemuth, Arsen Petrovic, Yaowen Wu, Philipp Selenko, Andrea Musacchio, Stefano Maffini
Publikováno v:
eLife, Vol 8 (2019)
Delivery of native or chemically modified recombinant proteins into mammalian cells shows promise for functional investigations and various technological applications, but concerns that sub-cellular localization and functional integrity of delivered
Externí odkaz:
https://doaj.org/article/902869c71fc7452698e6502e4d22125b
Autor:
Katharina Overlack, Ivana Primorac, Mathijs Vleugel, Veronica Krenn, Stefano Maffini, Ingrid Hoffmann, Geert J P L Kops, Andrea Musacchio
Publikováno v:
eLife, Vol 4 (2015)
The spindle assembly checkpoint (SAC) monitors and promotes kinetochore–microtubule attachment during mitosis. Bub1 and BubR1, SAC components, originated from duplication of an ancestor gene. Subsequent sub-functionalization established subordinati
Externí odkaz:
https://doaj.org/article/d58b367dc64a442eaf360a3ccefc8014
Autor:
Arsen Petrovic, Stephanie Voss, Giuseppe Ciossani, Valentina Piano, Katharina Overlack, Beate Voss, Stefano Maffini, Yao-Wen Wu, Philipp Selenko, Sabine Wohlgemuth, Marchel Stuiver, Andrea Musacchio, Amal Alex, Soumitra Polley
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::97fb0e509c56b5bfce1ef645a162cdfe
https://doi.org/10.7554/elife.48287.024
https://doi.org/10.7554/elife.48287.024
Autor:
Andrea Musacchio, Giuseppe Ciossani, Katharina Overlack, Huis in ‘t Veld P, Sabine Wohlgemuth, Stefano Maffini, Körner C, Arsen Petrovic
The metazoan proteins CENP-E and CENP-F are components of a fibrous layer of mitotic kinetochores named the corona. Several features suggest that CENP-E and CENP-F are paralogs: they are very large (approximately 2700 and 3200 residues, respectively)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e5bdcb360d2889cb3bd1ae01621a735
Publikováno v:
Current Biology. 24:29-39
Summary Background The KMN network, a ten-subunit protein complex, mediates the interaction of kinetochores with spindle microtubules and recruits spindle assembly checkpoint (SAC) constituents to halt cells in mitosis until attainment of sister chro
Publikováno v:
EMBO Reports
The faithful segregation of chromosomes into daughter cells is essential for cellular and organismal viability. Errors in this process cause aneuploidy, a hallmark of cancer and several congenital diseases. For proper separation, chromosomes attach t
Autor:
Stefano Maffini, Veronica Krenn, Katharina Overlack, Ingrid Hoffmann, Geert J. P. L. Kops, Ivana Primorac, Andrea Musacchio, Mathijs Vleugel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e4ddf5621e0b65dfebc643393fb93926
https://doi.org/10.7554/elife.05269.019
https://doi.org/10.7554/elife.05269.019
Autor:
Ingrid Hoffmann, Stefano Maffini, Mathijs Vleugel, Andrea Musacchio, Katharina Overlack, Veronica Krenn, Ivana Primorac, Geert J. P. L. Kops
Publikováno v:
eLife, Vol 4 (2015)
eLife
eLife
The spindle assembly checkpoint (SAC) monitors and promotes kinetochore–microtubule attachment during mitosis. Bub1 and BubR1, SAC components, originated from duplication of an ancestor gene. Subsequent sub-functionalization established subordinati
Autor:
Jan-Michael Peters, Stefano Maffini, Ivana Primorac, Alex C. Faesen, Tanja Bange, Florian Weissmann, Franziska Müller, Katharina Overlack, Andrea Musacchio
Publikováno v:
Current Biology
Summary The spindle assembly checkpoint (SAC) prevents premature sister chromatid separation during mitosis. Phosphorylation of unattached kinetochores by the Mps1 kinase promotes recruitment of SAC machinery that catalyzes assembly of the SAC effect
Autor:
Sabine Wohlgemuth, Katharina Overlack, Valentina Cecatiello, Marta Mattiuzzo, Veronica Krenn, Sebastiano Pasqualato, Stefan Raunser, Arsen Petrovic, Anna De Antoni, Jenny Keller, Andrea Musacchio, Shyamal Mosalaganti
Faithful chromosome segregation is mandatory for cell and organismal viability. Kinetochores, large protein assemblies embedded in centromeric chromatin, establish a mechanical link between chromosomes and spindle microtubules. The KMN network, a con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::994a8c318b49668ec92e9bcf01650997