Zobrazeno 1 - 10 of 17 pro vyhledávání: '"Katharina Mack"'
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Akademický článek
Dual Targeting of Tumor Cells with Bispecific Single-Chain Fv-Immunoliposomes
Autor: Katharina Mack, Ronny Rüger, Sina Fellermeier, Oliver Seifert, Roland E. Kontermann
Publikováno v: Antibodies, Vol 1, Iss 2, Pp 199-214 (2012)
Antibody fragments, especially single-chain Fv fragments, have been established for the generation of immunoliposomes for targeted drug delivery in cancer therapy and other applications. Bispecific immunoliposomes should be useful for dual targeting
Externí odkaz: https://doaj.org/article/e0a7bbe07f3142828a778efdc4422816
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2
cAIMPadministration in humanized mice induces a chimerization‐level‐dependentSTINGresponse
Autor: Martin R. Jakobsen, Martin K. Thomsen, Lars Østergaard, Rikke Olesen, Katharina Mack, Christian Krapp, Jesper F Højen, Martin Tolstrup, Frederik Dagnæs-Hansen, Paul W. Denton, Anna H. F. Andersen, Kasper L Jønsson
Publikováno v: Andersen, A H F, Olesen, R, Jønsson, K L, Højen, J F, Krapp, C, Mack, K, Thomsen, M K, Østergaard, L, Tolstrup, M, Dagnæs-Hansen, F, Jakobsen, M R & Denton, P W 2019, ' cAIMP administration in humanized mice induces a chimerization-level-dependent STING response ', Immunology, vol. 157, no. 2, pp. 163-172 . https://doi.org/10.1111/imm.13061
Andersen, A H F, Olesen, R, Jønsson, K L, Højen, J F, Krapp, C, Mack, K, Thomsen, M K, Østergaard, L, Tolstrup, M, Dagnaes-Hansen, F, Jacobsen, M R & Denton, P W 2019, ' cAIMP administration in humanized mice induces a chimerization-level-dependent STING response ' Immunology . https://doi.org/10.1111/imm.13061
Immunology
It is well conceived that the STING signalling pathway is critical for generating a robust innate immune response to pathogens. Human and mouse STING signaling pathways are not identical, however. For example, mice lack IFI16 which has been proven im
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a1f8f27964c177fba22bbf3f7aa9c1e
https://doi.org/10.1111/imm.13061
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3
Humanized NOG Mice for Intravaginal HIV Exposure and Treatment of HIV Infection
Autor: Paul W. Denton, Stine S F Nielsen, Frederik Dagnæs-Hansen, Rikke Olesen, Martin Tolstrup, Ole S. Søgaard, Katharina Mack, Niels Uldbjerg, Lars Østergaard, Anna H. F. Andersen
Publikováno v: Andersen, A H F, Nielsen, S S F, Olesen, R, Mack, K, Dagnæs-Hansen, N F, Uldbjerg, N, Østergaard, L J, Søgaard, O S, Denton, P W & Tolstrup, M 2020, ' Humanized NOG Mice for Intravaginal HIV Exposure and Treatment of HIV Infection ', Journal of Visualized Experiments, vol. 2020, no. 155, e60723 . https://doi.org/10.3791/60723
Humanized mice provide a sophisticated platform to study human immunodeficiency virus (HIV) virology and to test antiviral drugs. This protocol describes the establishment of a human immune system in adult NOG mice. Here, we explain all the practical
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05a9de203c505aa11ad3a1aad2be54fc
https://doi.org/10.3791/60723
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5
Effects of 24-week Toll-like receptor 9 agonist treatment in HIV type 1+ individuals
Autor: Ole Schmeltz Søgaard, Manuel Schmidt, Burghardt Wittig, Kaja Zuwala, Martin Tolstrup, Mariane H. Schleimann, Stephane Hua, Katharina Mack, Rikke Olesen, Anni Winckelmann, Line K. Vibholm, Mathias Lichterfeld, Sanne Skov Jensen, Vibeke Klastrup, Giacomo S. Frattari, Paul W. Denton, Nanna M. Jensen, Lars Østergaard, Christina V. Konrad
Publikováno v: Vibholm, L K, Konrad, C V, Schleimann, M H, Frattari, G, Winckelmann, A, Klastrup, V, Jensen, N M, Schmidt, M, Wittig, B, Zuwala, K, Mack, K, Olesen, R, Hua, S, Lichterfeld, M, Østergaard, L, Denton, P W, Tolstrup, M & Søgaard, O S 2019, ' Effects of 24-week Toll-like receptor 9 agonist treatment in HIV type 1+ individuals ', AIDS (London, England), vol. 33, no. 8, pp. 1315-1325 . https://doi.org/10.1097/QAD.0000000000002213
DESIGN: This was an exploratory, single-arm clinical trial that tested the immune enhancement effects of 24-weeks of Toll-like receptor 9 (TLR9) agonist (MGN1703; Lefitolimod; 60 mg × 2 weekly) therapy. METHODS: We enrolled HIV-1-infected individual
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97789671b5831b91f2f21413c994b460
https://pure.au.dk/portal/da/publications/effects-of-24week-tolllike-receptor-9-agonist-treatment-in-hiv-type-1-individuals(39a77657-f724-4206-a780-5a6b6139fc80).html
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6
Differential Control of BST2 Restriction and Plasmacytoid Dendritic Cell Antiviral Response by Antagonists Encoded by HIV-1 Group M and O Strains
Autor: Lijun Cong, Frank Kirchhoff, Éric A. Cohen, Katharina Mack, Mariana G. Bego
Publikováno v: Journal of Virology. 90:10236-10246
BST2/tetherin is a type I interferon (IFN-I)-stimulated host factor that restricts the release of HIV-1 by entrapping budding virions at the cell surface. This membrane-associated protein can also engage and activate the plasmacytoid dendritic cell (
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33cb5f66f24bb72933048358c7e4740b
https://doi.org/10.1128/jvi.01131-16
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7
Efficient Vpu-Mediated Tetherin Antagonism by an HIV-1 Group O Strain
Autor: Marie Leoz, Frank Kirchhoff, Beatrice H. Hahn, Matthias Geyer, Daniel Sauter, Jean-Christophe Plantier, Christina M. Stürzel, Simon Langer, Gerald H. Learn, Frederic Bibollet-Ruche, Kathrin Starz, Katharina Mack
Publikováno v: Journal of Virology
Journal of Virology, American Society for Microbiology, 2017, 91 (6), ⟨10.1128/JVI.02177-16⟩
Simian immunodeficiency viruses (SIVs) use their Nef proteins to counteract the restriction factor tetherin. However, a deletion in human tetherin prevents antagonism by the Nef proteins of SIVcpz and SIVgor, which represent the ape precursors of hum
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::857707ac9b14b7385d4d88d948932ae5
https://doi.org/10.1128/jvi.02177-16
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8
A Heteroleptic Push-Pull Substituted Iron(II) Bis(tridentate) Complex with Low-Energy Charge-Transfer States
Autor: Katharina Mack, Katja Heinze, Frédéric Laquai, Aaron Breivogel, Andreas K. C. Mengel, Julian Robert Ochsmann, Vadim Ksenofontov, Christoph Förster
Publikováno v: Chemistry - A European Journal. 21:704-714
A heteroleptic iron(II) complex [Fe(dcpp)(ddpd)](2+) with a strongly electron-withdrawing ligand (dcpp, 2,6-bis(2-carboxypyridyl)pyridine) and a strongly electron-donating tridentate tripyridine ligand (ddpd, N,N'-dimethyl-N,N'-dipyridine-2-yl-pyridi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::137561d9e8cdab2d4a289cb6fb0c8a2a
https://doi.org/10.1002/chem.201404955
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9
Alcohol-assisted base-free hydrogenation of acetophenone catalyzed by OsH(NHCMe2CMe2NH2)(PPh3)2
Autor: Marco Zimmer-De Iuliis, Sean E. Clapham, Robert H. Morris, Demyan E. Prokopchuk, Katharina Mack
Publikováno v: Canadian Journal of Chemistry. 92:731-738
The hydrido–amido complex OsH(NHCMe2CMe2NH2)(PPh3)2 (1) catalyzes the base-free hydrogenation of ketones in benzene. Kinetic studies using acetophenone revealed that the system has an induction period, after which the rate of the reaction increases
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d6c8ad6a4faa9513026b668d52bad9f6
https://doi.org/10.1139/cjc-2014-0060
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10
Coordination of expanded terpyridine ligands to cobalt
Autor: Vadim Ksenofontov, Katja Heinze, Eva Rentschler, Christoph Förster, Katharina Mack, Luca M. Carrella
Publikováno v: Polyhedron. 52:576-581
The tridentate expanded terpyridine-like ligand N,N′-dimethyl-N,N′-dipyridin-2-yl-pyridin-2,6-diamine (ddpd) and [Co(H2O)6](BF4)2 give the high-spin complex mer-[Co(ddpd)2](BF4)2 with a tetragonally compressed CoN6 coordination geometry according
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::27dc881066499f2bd340de482e0fec25
https://doi.org/10.1016/j.poly.2012.08.008
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