Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Katharina M. Hembach"'
Autor:
Jelena Scekic-Zahirovic, Inmaculada Sanjuan-Ruiz, Vanessa Kan, Salim Megat, Pierre De Rossi, Stéphane Dieterlé, Raphaelle Cassel, Marguerite Jamet, Pascal Kessler, Diana Wiesner, Laura Tzeplaeff, Valérie Demais, Sonu Sahadevan, Katharina M. Hembach, Hans-Peter Muller, Gina Picchiarelli, Nibha Mishra, Stefano Antonucci, Sylvie Dirrig-Grosch, Jan Kassubek, Volker Rasche, Albert Ludolph, Anne-Laurence Boutillier, Francesco Roselli, Magdalini Polymenidou, Clotilde Lagier-Tourenne, Sabine Liebscher, Luc Dupuis
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-19 (2021)
Mutations in the RNA binding protein FUS are associated with ALS. Here the authors show that in FUS knock-in mice there is a progressive increase in neuronal activity in the frontal cortex which is associated with altered synaptic gene expression.
Externí odkaz:
https://doaj.org/article/81d53965ba1c4f5cbe4fa11bc13113fd
Autor:
Sonu Sahadevan, Katharina M. Hembach, Elena Tantardini, Manuela Pérez-Berlanga, Marian Hruska-Plochan, Salim Megat, Julien Weber, Petra Schwarz, Luc Dupuis, Mark D. Robinson, Pierre De Rossi, Magdalini Polymenidou
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
Mutations in the RNA-binding protein FUS contribute to ALS. Here the authors use CLIP-seq on synaptoneurosomes to identify proteins associated with synapse organization and plasticity that are differentially regulated in a knock-in ALS mouse model.
Externí odkaz:
https://doaj.org/article/e9c043534e61495b8e1dfb249245ca1e
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 9, Iss 7, Pp 2089-2096 (2019)
The extensive generation of RNA sequencing (RNA-seq) data in the last decade has resulted in a myriad of specialized software for its analysis. Each software module typically targets a specific step within the analysis pipeline, making it necessary t
Externí odkaz:
https://doaj.org/article/b56266223896403d9b64de9d7bba7b26
Autor:
Pierre De Rossi, Marian Hruska-Plochan, Magdalini Polymenidou, Mark D. Robinson, Elena Tantardini, Luc Dupuis, Salim Megat, Julien Weber, Katharina M. Hembach, Petra Schwarz, Sonu Sahadevan, Manuela Pérez-Berlanga
Publikováno v:
Nature Communications
Nature Communications, 2021, 12 (1), pp.3027. ⟨10.1038/s41467-021-23188-8⟩
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
Nature Communications, Nature Publishing Group, 2021, 12 (1), pp.3027. ⟨10.1038/s41467-021-23188-8⟩
Nature Communications, 2021, 12 (1), pp.3027. ⟨10.1038/s41467-021-23188-8⟩
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
Nature Communications, Nature Publishing Group, 2021, 12 (1), pp.3027. ⟨10.1038/s41467-021-23188-8⟩
Mutations disrupting the nuclear localization of the RNA-binding protein FUS characterize a subset of amyotrophic lateral sclerosis patients (ALS-FUS). FUS regulates nuclear RNAs, but its role at the synapse is poorly understood. Using super-resoluti
Autor:
Mark D. Robinson, Katharina M. Hembach, Simone Tiberi, Charlotte Soneson, Michael I. Love, Koen Van den Berge, Lieven Clement, Rob Patro
Publikováno v:
Annual Review of Biomedical Data Science. 2:139-173
Gene expression is the fundamental level at which the results of various genetic and regulatory programs are observable. The measurement of transcriptome-wide gene expression has convincingly switched from microarrays to sequencing in a matter of yea
Autor:
Katharina M. Hembach, Elena Tantardini, Sonu Sahadevan, Mark D. Robinson, Marian Hruska-Plochan, Petra Schwarz, Julien Weber, Manuela Pérez-Berlanga, Luc Dupuis, Magdalini Polymenidou, P. de Rossi
FUS is a primarily nuclear RNA-binding protein with important roles in RNA processing and transport. FUS mutations disrupting its nuclear localization characterize a subset of amyotrophic lateral sclerosis (ALS-FUS) patients, through an unidentified
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2b0b2073a3afa95a2ed4c1f16cc987bc
https://doi.org/10.1101/2020.06.10.136010
https://doi.org/10.1101/2020.06.10.136010
Publikováno v:
G3: Genes|Genomes|Genetics
The extensive generation of RNA sequencing (RNA-seq) data in the last decade has resulted in a myriad of specialized software for its analysis. Each software module typically targets a specific step within the analysis pipeline, making it necessary t