Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Katharina L. Willmann"'
Autor:
Jacques Neefjes, Josef Anrather, Vladimir Benes, Luis F. Moita, Michael Sattler, Sebastian Weis, André Barros, Raffaella Gozzelino, Ângelo Chora, Henrique G. Colaço, Miguel P. Soares, Arie Geerlof, Pedro Pereira, Eleni Kyriakou, Isa Santos, Nadja Pejanovic, Katharina L. Willmann, Catarina Moita, Tiago R. Velho, Sérgio F. de Almeida, Dora Pedroso, João A. Ferreira, Filipa Batalha Martins, Sílvia Carvalho, Ana C. Messias, Ana Neves-Costa
Publikováno v:
SSRN Electronic Journal.
Anthracyclines are among the most used and effective anticancer drugs. Their activity has been attributed to DNA double-strand breaks resulting from topoisomerase II poisoning and to eviction of histones from select sites in the genome. Here we show
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6cc6b5093b6569991ee037f0c307011f
https://doi.org/10.2139/ssrn.3875775
https://doi.org/10.2139/ssrn.3875775
Autor:
Adrián César-Razquin, Manuele Rebsamen, Manuela Bruckner, Leonhard X. Heinz, Katrin Hörmann, Giulio Superti-Furga, Justyna Konecka, Astrid Fauster, Stefania Scorzoni, Fiorella Schischlik, Katharina L. Willmann, Johannes W. Bigenzahn, Enrico Girardi, Kaan Boztug
Publikováno v:
Cell Death and Differentiation
Cell Death & Differentiation
Cell Death & Differentiation
Regulation of cell and tissue homeostasis by programmed cell death is a fundamental process with wide physiological and pathological implications. The advent of scalable somatic cell genetic technologies creates the opportunity to functionally map su
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad9056591d299f04db2c67dc4ad496de
https://doi.org/10.1038/s41418-018-0192-6
https://doi.org/10.1038/s41418-018-0192-6
Autor:
Dora Pedroso, Gerlinde Grabmann, Elsa Seixas, Hyon-Seung Yi, Luis F. Moita, Minho Shong, Thomas D. Kocher, Pedro Faísca, Vladimir Benes, Henrique G. Colaço, Tiago R. Velho, Katharina L. Willmann, Ana Neves-Costa, Sebastian Weis, André Barros
Publikováno v:
Cell Mol Immunol
Immunity
Immunity
Several classes of antibiotics have long been known to have beneficial effects that cannot be explained strictly on the basis of their capacity to control the infectious agent. Here, we report that tetracycline antibiotics, which target the mitoribos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::caf8bfb7e1f4345365d28b9d7f11402f
https://pubmed.ncbi.nlm.nih.gov/33864005
https://pubmed.ncbi.nlm.nih.gov/33864005
Autor:
Katharina L. Willmann, Henrique G. Colaço, Hyon-Seung Yi, Sebastian Weis, André Barros, Ana Neves-Costa, Elsa Seixas, Thomas D. Kocher, Dora Pedroso, Tiago R. Velho, Vladimir Benes, Luis F. Moita, Minho Shong
SummarySynergy of resistance and disease tolerance mechanisms is necessary for an effective immune response leading to survival and return to homeostasis when an organism is challenged by infection. Antibiotics are used for their resistance enhanceme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8093f9ac87b25676e06bb8f0c452b9a
Autor:
Enrico Girardi, van der Burg M, Javier Martinez, Rico Chandra Ardy, Cecilia Domínguez Conde, Elisabeth Salzer, Ahmet Ozen, Özlem Yüce Petronczki, Stefan Weitzer, Kaan Boztug, Ana Krolo, Winfried F. Pickl, Ijspeert H, Katharina L. Willmann, Elif Karakoc-Aydiner, Safa Baris, Ayca Kiykim, Giulio Superti-Furga, Leo Kager, Joanna I. Loizou, Elisabeth Förster-Waldl
Publikováno v:
Journal of Clinical Investigation, 129(10), 4194-4206. AMER SOC CLINICAL INVESTIGATION INC
Polymerase delta is essential for eukaryotic genome duplication and synthesizes DNA at both the leading and lagging strands. The polymerase delta complex is a heterotetramer comprising the catalytic subunit POLD1 and the accessory subunits POLD2, POL
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fd94005bae7aeaafaad7ae447e5c8ef
http://hdl.handle.net/1887/121733
http://hdl.handle.net/1887/121733
Autor:
Miroslav Hons, Winfried F. Pickl, Sol A. Ban, Johannes B. Huppa, Ozden Sanal, Fabienne McClanahan, Gerhard J. Zlabinger, Papiya Sinha, John G. Gribben, Elisabeth Salzer, Wojciech Garncarz, Kaan Boztug, Michael Sixt, Deniz Cagdas, Emily M. Mace, Loïc Dupré, Katharina L. Willmann, Ilhan Tezcan, Keiryn L. Bennett, René Platzer, Hsiang-Ting Hsu, Ivan Bilic, Pinaki P. Banerjee, Malini Mukherjee, Hannes Stockinger, Verena Supper, Özlem Yüce Petronczki, Laurène Pfajfer, Ulrich Jäger, Jordan S. Orange
Publikováno v:
Nature Immunology. 17:1352-1360
RASGRP1 is an important guanine nucleotide exchange factor and activator of the RAS-MAPK pathway following T cell antigen receptor (TCR) signaling. The consequences of RASGRP1 mutations in humans are unknown. In a patient with recurrent bacterial and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dce4086a382555498c09e51802d63377
https://doi.org/10.1038/ni.3575
https://doi.org/10.1038/ni.3575
Autor:
Maria T. Simon, Isabelle Robert, Vincent Heyer, Kerstin-Maike Schmitz, Sara Milosevic, Sarah L. Maslen, Mark Skehel, Katharina L. Willmann, Siim Pauklin, Bernardo Reina-San-Martin, Gopinath Rangam, Svend K. Petersen-Mahrt, Ebe Schiavo
Publikováno v:
The Journal of Experimental Medicine
Antibody diversification requires the DNA deaminase AID to induce DNA instability at immunoglobulin (Ig) loci upon B cell stimulation. For efficient cytosine deamination, AID requires single-stranded DNA and needs to gain access to Ig loci, with RNA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::477198828b4f1fc2c142ab7964ac520e
https://doi.org/10.1084/jem.20112145
https://doi.org/10.1084/jem.20112145
Autor:
Svend K. Petersen-Mahrt, Anne Durandy, Pauline Gardès, Katharina L. Willmann, Sven Kracker, Don-Marc Franchini, Maria T. Simon
Publikováno v:
DNA Deamination and the Immune System: AID in Health and Disease
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::793574189337ec443dd7334cecca56d3
https://doi.org/10.1142/9781848165939_0008
https://doi.org/10.1142/9781848165939_0008