Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Katharina Isabell Maser"'
Autor:
Tina Schumann, Santiago Costas Ramon, Nadja Schubert, Mohamad Aref Mayo, Melanie Hega, Katharina Isabell Maser, Servi-Remzi Ada, Lukas Sydow, Mona Hajikazemi, Markus Badstübner, Patrick Müller, Yan Ge, Farhad Shakeri, Andreas Buness, Benjamin Rupf, Stefan Lienenklaus, Barbara Utess, Lina Muhandes, Michael Haase, Luise Rupp, Marc Schmitz, Thomas Gramberg, Nicolas Manel, Gunther Hartmann, Thomas Zillinger, Hiroki Kato, Stefan Bauer, Alexander Gerbaulet, Katrin Paeschke, Axel Roers, Rayk Behrendt
Publikováno v:
Journal of Experimental Medicine. 220
Defects in nucleic acid metabolizing enzymes can lead to spontaneous but selective activation of either cGAS/STING or RIG-like receptor (RLR) signaling, causing type I interferon–driven inflammatory diseases. In these pathophysiological conditions,
Autor:
Shovamayee Maharana, Stefanie Kretschmer, Susan Hunger, Xiao Yan, David Kuster, Sofia Traikov, Thomas Zillinger, Marc Gentzel, Nagaraja Chappidi, Nadja Lucas, Katharina Isabell Maser, Henrike Maatz, Alexander Rapp, Virginie Marchand, K. Venkatesan Iyer, Akshita Chhabra, Young-Tae Chang, Yuri Motorin, Norbert Hubner, Gunther Hartmann, Anthony Hyman, Simon Alberti, Min Ae Lee-Kirsch
Publikováno v:
Molecular cell. 82(19)
Recognition of pathogen-derived foreign nucleic acids is central to innate immune defense. This requires discrimination between structurally highly similar self and nonself nucleic acids to avoid aberrant inflammatory responses as in the autoinflamma