Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Katharina Hecklau"'
Autor:
Katharina Hecklau, Susanne Mueller, Stefan Paul Koch, Mustafa Hussain Mehkary, Busra Kilic, Christoph Harms, Philipp Boehm-Sturm, Ferah Yildirim
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 14 (2021)
Huntington’s disease (HD) is an autosomal dominant neurodegenerative disease characterized by a late clinical onset of psychiatric, cognitive, and motor symptoms. Transcriptional dysregulation is an early and central disease mechanism which is acco
Externí odkaz:
https://doaj.org/article/f9766f01a40d417fa1324980494d2886
Autor:
Katharina Hecklau, Christian H. Gabriel, Andreas Radbruch, Christian Sommer, Matthias Selbach, Martin Karl, Anna Floriane Hennig, Ria Baumgrass, Melanie Venzke
Publikováno v:
Journal of Molecular Biology. 431:3606-3625
Differentiation toward CD4+ regulatory T (Treg) cells is essentially dependent on an epigenetic program at Treg signature genes, which involves remodeling of the Treg-specific demethylated regions (TSDRs). In particular, the epigenetic status of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c025850ad1d246b748d7e18546673400
https://doi.org/10.1016/j.jmb.2019.07.031
https://doi.org/10.1016/j.jmb.2019.07.031
Autor:
Susanne Mueller, Mustafa Hussain Mehkary, Busra Kilic, Stefan Koch, Christoph Harms, Ferah Yildirim, Katharina Hecklau, Philipp Boehm-Sturm
Huntington’s disease (HD) is an autosomal dominant neurodegenerative disease characterized by a late clinical onset of psychiatric, cognitive, and motor symptoms. Transcriptional dysregulation is an early and central disease mechanism which is acco
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3e1cb8190a77d7366f8e59a8197f25a2
https://doi.org/10.1101/2020.10.13.337154
https://doi.org/10.1101/2020.10.13.337154
Autor:
Stefanie Gryzik, Jürgen Wienands, Martin Karl, Melanie Weber, Johannes Schuchhardt, Katharina Hecklau, Fridolin Gross, Ivo Bachmann, Ria Baumgrass, Hanspeter Herzel, Heike Stephanowitz, Christian H. Gabriel, Eberhard Krause, Anna Floriane Hennig, Andreas Radbruch
Publikováno v:
Journal of applied biological chemistry, 291(46), 24172-24187
Transcription factors of the nuclear factor of activated T cell (NFAT) family are essential for antigen-specific T cell activation and differentiation. Their cooperative DNA binding with other transcription factors, such as AP1 proteins (FOS, JUN, an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d52e6e90fa4b2a905338e51829c08cc
https://doi.org/10.1074/jbc.m116.739326
https://doi.org/10.1074/jbc.m116.739326
Autor:
Zhuo Fang, Katharina Hecklau, Fridolin Gross, Martin Karl, Johannes Schuchhardt, Ivo Bachmann, Melanie Venzke, Andreas Radbruch, Ria Baumgrass, Hanspeter Herzel
Publikováno v:
European Journal of Immunology. 45:3150-3157
Transcription factors (TFs) regulate cell-type-specific gene expression programs by combinatorial binding to cis-genomic elements, particularly enhancers, subsequently leading to the recruitment of cofactors, and the general transcriptional machinery
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eb532de6846ba83ac778970d371ef128
https://doi.org/10.1002/eji.201545713
https://doi.org/10.1002/eji.201545713