Assessing the function of pneumococcal neuraminidases NanA, NanB and NanC in in vitro and in vivo lung infection models using monoclonal antibodies

Autor: Philipp Janesch, Harald Rouha, Adriana Badarau, Lukas Stulik, Irina Mirkina, Marisa Caccamo, Katharina Havlicek, Barbara Maierhofer, Susanne Weber, Karin Groß, Jacqueline Steinhäuser, Manuel Zerbs, Cecilia Varga, Ivana Dolezilkova, Sabine Maier, Gerhild Zauner, Nels Nielson, Christine A. Power, Eszter Nagy

Publikováno v: Virulence, Vol 9, Iss 1, Pp 1521-1538 (2018)

Streptococcus pneumoniae isolates express up to three neuraminidases (sialidases), NanA, NanB and NanC, all of which cleave the terminal sialic acid of glycan-structures that decorate host cell surfaces. Most research has focused on the role of NanA

Externí odkaz: https://doaj.org/article/3d6e41b7d535455faecc94e43c18d40e

Endocytosis is required for access of surface-bound cargo to the flagellar pocket of trypanosomes

Autor: Daja Schichler, Eva-Maria Spath, Antonia Konle, Sina Riegler, Alexandra Klein, Anna Seleznev, Sisco Jung, Tim Wuppermann, Noah Wetterich, Alyssa Borges, Elisabeth Meyer-Natus, Katharina Havlicek, Sonia Pérez Cabrera, Korbinian Niedermüller, Sara Sajko, Maximilian Dohn, Xenia Malzer, Emily Riemer, Tuguldur Tumurbaatar, Kristina Djinovic-Carugo, Gang Dong, Christian J. Janzen, Brooke Morriswood

All endo- and exocytosis in the African trypanosome Trypanosoma brucei occurs at a single subdomain of the plasma membrane. This subdomain, the flagellar pocket, is a small vase-shaped invagination containing the root of the cell’s single flagellum

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2998053caff398934b0f6ab41b304e46
https://doi.org/10.1101/2022.03.15.484455

Bhalin, an essential cytoskeleton-associated protein of Trypanosoma brucei linking TbBILBO1 of the flagellar pocket collar with the hook complex

Autor: Anne Cayrel, Denis Dacheux, Amélie Mailhé, Corentin Agnero-Rigot, Christine E. Broster Reix, Brooke Morriswood, Nicolas Landrein, Katharina Havlicek, Célia Florimond, Derrick R. Robinson, Mélanie Bonhivers

Publikováno v: Microorganisms, Vol 9, Iss 2334, p 2334 (2021)
Microorganisms
Microorganisms, MDPI, 2021, 9 (11), pp.2334. ⟨10.3390/microorganisms9112334⟩
Volume 9
Issue 11

Background: In most trypanosomes, endo and exocytosis only occur at a unique organelle called the flagellar pocket (FP) and the flagellum exits the cell via the FP. Investigations of essential cytoskeleton-associated structures located at this site h

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b3a7a9aba134788e3b23efe34f93a71
https://doi.org/10.3390/microorganisms9112334