Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Katharina Gunkel"'
Autor:
Frank Winkler, Wolfgang Wick, Matthias Preusser, Patricia S. Steeg, Andreas Trumpp, Miriam Ratliff, Carina M. Thome, Petra Rübmann, Lulu Huang, Miriam Gömmel, Gergely Solecki, Michael O. Breckwoldt, Natalia Becker, Felix Sahm, Zuszanna Bago-Horvath, Laura L. Michel, Frederic Marmé, Brunhilde Gril, Manuel Feinauer, Susanne Wünsche, Matthias Osswald, Tobias Kessler, Christian Eisen, Martin R. Sprick, Katharina Gunkel, Ayseguel Ilhan-Mutlu, Matthia A. Karreman, Yunxiang Liao, Anna. S. Berghoff
Specific biological properties of those circulating cancer cells that are the origin of brain metastases (BM) are not well understood. Here, single circulating breast cancer cells were fate-tracked during all steps of the brain metastatic cascade in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4430eee691997f3dfbf7daec9f854e4b
https://doi.org/10.1158/1541-7786.c.6545246.v1
https://doi.org/10.1158/1541-7786.c.6545246.v1
Autor:
Frank Winkler, Wolfgang Wick, Matthias Preusser, Patricia S. Steeg, Andreas Trumpp, Miriam Ratliff, Carina M. Thome, Petra Rübmann, Lulu Huang, Miriam Gömmel, Gergely Solecki, Michael O. Breckwoldt, Natalia Becker, Felix Sahm, Zuszanna Bago-Horvath, Laura L. Michel, Frederic Marmé, Brunhilde Gril, Manuel Feinauer, Susanne Wünsche, Matthias Osswald, Tobias Kessler, Christian Eisen, Martin R. Sprick, Katharina Gunkel, Ayseguel Ilhan-Mutlu, Matthia A. Karreman, Yunxiang Liao, Anna. S. Berghoff
Supplementary Figure 3 shows PKH26 intensity and depth of the cell in relation to the successful establishment of a metastasis. Further, the brain metastatic cascade for PKH26 low (slow cycling) and PKH26 (high) (ultra slow cycling) cells is illustra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39c4f4c45bd22576427dc0818fd7bd65
https://doi.org/10.1158/1541-7786.22526921.v1
https://doi.org/10.1158/1541-7786.22526921.v1
Autor:
Frank Winkler, Wolfgang Wick, Matthias Preusser, Patricia S. Steeg, Andreas Trumpp, Miriam Ratliff, Carina M. Thome, Petra Rübmann, Lulu Huang, Miriam Gömmel, Gergely Solecki, Michael O. Breckwoldt, Natalia Becker, Felix Sahm, Zuszanna Bago-Horvath, Laura L. Michel, Frederic Marmé, Brunhilde Gril, Manuel Feinauer, Susanne Wünsche, Matthias Osswald, Tobias Kessler, Christian Eisen, Martin R. Sprick, Katharina Gunkel, Ayseguel Ilhan-Mutlu, Matthia A. Karreman, Yunxiang Liao, Anna. S. Berghoff
Supplementary Figure 4 shows IVIS results.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ca60a7e087ea9573afa334776c9cc81
https://doi.org/10.1158/1541-7786.22526918
https://doi.org/10.1158/1541-7786.22526918
Autor:
Frank Winkler, Wolfgang Wick, Matthias Preusser, Patricia S. Steeg, Andreas Trumpp, Miriam Ratliff, Carina M. Thome, Petra Rübmann, Lulu Huang, Miriam Gömmel, Gergely Solecki, Michael O. Breckwoldt, Natalia Becker, Felix Sahm, Zuszanna Bago-Horvath, Laura L. Michel, Frederic Marmé, Brunhilde Gril, Manuel Feinauer, Susanne Wünsche, Matthias Osswald, Tobias Kessler, Christian Eisen, Martin R. Sprick, Katharina Gunkel, Ayseguel Ilhan-Mutlu, Matthia A. Karreman, Yunxiang Liao, Anna. S. Berghoff
Supplementary Figure 6 shows NDRG1 expression in several cell lines.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98ee072f60fd406802d4d3c4bea0a695
https://doi.org/10.1158/1541-7786.22526912
https://doi.org/10.1158/1541-7786.22526912
Autor:
Frank Winkler, Wolfgang Wick, Matthias Preusser, Patricia S. Steeg, Andreas Trumpp, Miriam Ratliff, Carina M. Thome, Petra Rübmann, Lulu Huang, Miriam Gömmel, Gergely Solecki, Michael O. Breckwoldt, Natalia Becker, Felix Sahm, Zuszanna Bago-Horvath, Laura L. Michel, Frederic Marmé, Brunhilde Gril, Manuel Feinauer, Susanne Wünsche, Matthias Osswald, Tobias Kessler, Christian Eisen, Martin R. Sprick, Katharina Gunkel, Ayseguel Ilhan-Mutlu, Matthia A. Karreman, Yunxiang Liao, Anna. S. Berghoff
Supplementary Figure 1 A-C shows loss of PKH26 over time. Supplementary Figure 1 D shows an additional example of a slow cycling cells with remaining PKH26 staining in vivo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::280b6e3b416bf36f12f9ce8d010ecff4
https://doi.org/10.1158/1541-7786.22526927
https://doi.org/10.1158/1541-7786.22526927
Autor:
Frank Winkler, Wolfgang Wick, Matthias Preusser, Patricia S. Steeg, Andreas Trumpp, Miriam Ratliff, Carina M. Thome, Petra Rübmann, Lulu Huang, Miriam Gömmel, Gergely Solecki, Michael O. Breckwoldt, Natalia Becker, Felix Sahm, Zuszanna Bago-Horvath, Laura L. Michel, Frederic Marmé, Brunhilde Gril, Manuel Feinauer, Susanne Wünsche, Matthias Osswald, Tobias Kessler, Christian Eisen, Martin R. Sprick, Katharina Gunkel, Ayseguel Ilhan-Mutlu, Matthia A. Karreman, Yunxiang Liao, Anna. S. Berghoff
Supplementary Figure 5 shows cell cycle analysis.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d0873bcbaa9a5d52e3d53398b97d8f2
https://doi.org/10.1158/1541-7786.22526915
https://doi.org/10.1158/1541-7786.22526915
Autor:
Frank Winkler, Wolfgang Wick, Matthias Preusser, Patricia S. Steeg, Andreas Trumpp, Miriam Ratliff, Carina M. Thome, Petra Rübmann, Lulu Huang, Miriam Gömmel, Gergely Solecki, Michael O. Breckwoldt, Natalia Becker, Felix Sahm, Zuszanna Bago-Horvath, Laura L. Michel, Frederic Marmé, Brunhilde Gril, Manuel Feinauer, Susanne Wünsche, Matthias Osswald, Tobias Kessler, Christian Eisen, Martin R. Sprick, Katharina Gunkel, Ayseguel Ilhan-Mutlu, Matthia A. Karreman, Yunxiang Liao, Anna. S. Berghoff
Supplementary Figure 2 cell index of PKH26 stained cells, the overlap of PKH26 loss and 2 other methods of cell division analysis as well as the reversion of a slow cycling cell population to a mixed cycling population.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12dcd0bc72f8760f52cb915bfb184440
https://doi.org/10.1158/1541-7786.22526924
https://doi.org/10.1158/1541-7786.22526924
Autor:
Michael O. Breckwoldt, Manuel Feinauer, Wolfgang Wick, Varun Venkataramani, Katharina Gunkel, Maik Brune, Frank Winkler, Frank Thomas Mayer, Stefan W. Schneider, Anna S. Berghoff, Alexander Bauer, Bogdana Kovalchuk, Julia Grosch, Gergely Solecki, Jose Ramon Robador, Yannik Schwab, Matthia A. Karreman, Manuel Fischer, Cedric Tehranian
Publikováno v:
Blood
Clinically relevant brain metastases (BMs) frequently form in cancer patients, with limited options for effective treatment. Circulating cancer cells must first permanently arrest in brain microvessels to colonize the brain, but the critical factors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd6d5ce8de4a5db2c65a9dc104c4c02b
https://doi.org/10.1182/blood.2020005710
https://doi.org/10.1182/blood.2020005710
Autor:
Carina M. Thome, Frederic Marmé, Susanne Wünsche, Felix Sahm, Miriam Gömmel, P. S. Steeg, Miriam Ratliff, Wolfgang Wick, Yunxiang Liao, Brunhilde Gril, Frank Winkler, Matthias Preusser, Petra Rübmann, Matthias Osswald, Natalia Becker, Christian Eisen, Lulu Huang, Laura Michel, Manuel Feinauer, Martin R. Sprick, Andreas Trumpp, Ayseguel Ilhan-Mutlu, Tobias Kessler, Michael O. Breckwoldt, Katharina Gunkel, Matthia A. Karreman, Anna S. Berghoff, Zuszanna Bago-Horvath, Gergely Solecki
Publikováno v:
Mol Cancer Res
Specific biological properties of those circulating cancer cells that are the origin of brain metastases (BM) are not well understood. Here, single circulating breast cancer cells were fate-tracked during all steps of the brain metastatic cascade in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71f2308cebf58f0f67a1f52b9b382c1f
https://europepmc.org/articles/PMC9281611/
https://europepmc.org/articles/PMC9281611/