Zobrazeno 1 - 10
of 110
pro vyhledávání: '"Katharina Grabmeier-Pfistershammer"'
Autor:
Maximilian A. Funk, Judith Leitner, Marlene C. Gerner, Jasmin M. Hammerler, Benjamin Salzer, Manfred Lehner, Claire Battin, Simon Gumpelmair, Karin Stiasny, Katharina Grabmeier-Pfistershammer, Peter Steinberger
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Abstract Interactions of membrane-resident proteins are important targets for therapeutic interventions but most methods to study them are either costly, laborious or fail to reflect the physiologic interaction of membrane resident proteins in trans.
Externí odkaz:
https://doaj.org/article/257b54ec26e3422c8d71418d9801de66
Autor:
Al Nasar Ahmed Sehgal, Jera Safran, Bernhard Kratzer, Pia Gattinger, Robert B. Stieger, Laszlo Musiejovsky, Doris Trapin, Paul Ettel, Ulrike Körmöczi, Arno Rottal, Kristina Borochova, Yulia Dorofeeva, Inna Tulaeva, Milena Weber, Katharina Grabmeier-Pfistershammer, Thomas Perkmann, Ursula Wiedermann, Rudolf Valenta, Winfried F. Pickl
Publikováno v:
Vaccines, Vol 12, Iss 4, p 377 (2024)
Background: COVID-19, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has now become endemic and is currently one of the important respiratory virus infections regularly affecting mankind. The assessment of immunity against SA
Externí odkaz:
https://doaj.org/article/a38095d367404c3492f620969ca500df
Autor:
Isabelle Weinhofer, Paulus Rommer, Andreas Gleiss, Markus Ponleitner, Bettina Zierfuss, Petra Waidhofer-Söllner, Stéphane Fourcade, Katharina Grabmeier-Pfistershammer, Marie-Christine Reinert, Jens Göpfert, Anne Heine, Hemmo A.F. Yska, Carlos Casasnovas, Verónica Cantarín, Caroline G. Bergner, Eric Mallack, Sonja Forss-Petter, Patrick Aubourg, Annette Bley, Marc Engelen, Florian Eichler, Troy C. Lund, Aurora Pujol, Wolfgang Köhler, Jörn-Sven Kühl, Johannes Berger
Publikováno v:
EBioMedicine, Vol 96, Iss , Pp 104781- (2023)
Summary: Background: X-linked adrenoleukodystrophy (X-ALD) is highly variable, ranging from slowly progressive adrenomyeloneuropathy to severe brain demyelination and inflammation (cerebral ALD, CALD) affecting males with childhood peak onset. Risk m
Externí odkaz:
https://doaj.org/article/275297f07de64a75ad4b82604a75b650
Autor:
Bettina Zierfuss, Agnieszka Buda, Andrea Villoria-González, Maxime Logist, Jure Fabjan, Patricia Parzer, Claire Battin, Streggi Vandersteene, Inge M. E. Dijkstra, Petra Waidhofer-Söllner, Katharina Grabmeier-Pfistershammer, Peter Steinberger, Stephan Kemp, Sonja Forss-Petter, Johannes Berger, Isabelle Weinhofer
Publikováno v:
Journal of Neuroinflammation, Vol 19, Iss 1, Pp 1-20 (2022)
Abstract Saturated very long-chain fatty acids (VLCFA, ≥ C22), enriched in brain myelin and innate immune cells, accumulate in X-linked adrenoleukodystrophy (X-ALD) due to inherited dysfunction of the peroxisomal VLCFA transporter ABCD1. In its sev
Externí odkaz:
https://doaj.org/article/28432a9f70e04eb791392053b1e9a1b7
Autor:
Judith Leitner, Ricarda Egerer, Petra Waidhofer-Söllner, Katharina Grabmeier-Pfistershammer, Peter Steinberger
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionTargeting costimulatory receptors of the tumor necrosis factor receptor (TNFR) superfamily with agonistic antibodies is a promising approach in cancer immuno therapy. It is known that their efficacy strongly depends on FcγR cross-linking
Externí odkaz:
https://doaj.org/article/ac4c5ca60e9041e5836d41c22ae6c8d8
Autor:
Nina Worel, Katharina Grabmeier-Pfistershammer, Bernhard Kratzer, Martina Schlager, Andreas Tanzmann, Arno Rottal, Ulrike Körmöczi, Edit Porpaczy, Philipp B. Staber, Cathrin Skrabs, Harald Herkner, Venugopal Gudipati, Johannes B. Huppa, Benjamin Salzer, Manfred Lehner, Nora Saxenhuber, Eleonora Friedberg, Philipp Wohlfarth, Georg Hopfinger, Werner Rabitsch, Ingrid Simonitsch-Klupp, Ulrich Jäger, Winfried F. Pickl
Publikováno v:
Frontiers in Immunology, Vol 13 (2023)
BackgroundChimeric antigen receptor T (CART) cell therapy targeting the B cell specific differentiation antigen CD19 has shown clinical efficacy in a subset of relapsed/refractory (r/r) diffuse large B cell lymphoma (DLBCL) patients. Despite this het
Externí odkaz:
https://doaj.org/article/b9b90c9752894772a6c70577e2f23cde
Autor:
Lisa Göschl, Daniel Mrak, Katharina Grabmeier-Pfistershammer, Karin Stiasny, Helmuth Haslacher, Lisa Schneider, Thomas Deimel, Felix Kartnig, Selma Tobudic, Daniel Aletaha, Heinz Burgmann, Michael Bonelli, Winfried F. Pickl, Elisabeth Förster-Waldl, Clemens Scheinecker, Matthias Gerhard Vossen
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
BackgroundPatients with inborn errors of immunity (IEI) are at increased risk for severe courses of SARS-CoV-2 infection. COVID-19 vaccination provides effective protection in healthy individuals. However, it remains unclear whether vaccination is ef
Externí odkaz:
https://doaj.org/article/001e434e71d649d2b8ae169ff61c696f
Autor:
Claire Battin, Judith Leitner, Petra Waidhofer-Söllner, Katharina Grabmeier-Pfistershammer, Daniel Olive, Peter Steinberger
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
The engagement of the herpesvirus entry mediator (HVEM, TNFRSF14) by the B and T lymphocyte attenuator (BTLA) represents a unique interaction between an activating receptor of the TNFR-superfamily and an inhibitory receptor of the Ig-superfamily. BTL
Externí odkaz:
https://doaj.org/article/84cd7a7441634f1980d6fdf0b9a061ad
Autor:
Johannes J. Kovarik, Anna K. Kämpf, Fabian Gasser, Anna N. Herdina, Monika Breuer, Christopher C. Kaltenecker, Markus Wahrmann, Susanne Haindl, Florian Mayer, Ludwig Traby, Veronique Touzeau-Roemer, Katharina Grabmeier-Pfistershammer, Manuel Kussmann, Oliver Robak, Harald Willschke, Care Ay, Marcus D. Säemann, Klaus G. Schmetterer, Robert Strassl
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 11 (2021)
This study aimed to determine the specific cytokine profile in peripheral blood during the early onset of COVID-19 infection. This was a cross-sectional exploratory, single center study. A total of 55 plasma samples were studied. Serum samples of adu
Externí odkaz:
https://doaj.org/article/4bf28112b3c14942b95ed99c9282e9a8
Autor:
Johannes Griss, Wolfgang Bauer, Christine Wagner, Martin Simon, Minyi Chen, Katharina Grabmeier-Pfistershammer, Margarita Maurer-Granofszky, Florian Roka, Thomas Penz, Christoph Bock, Gao Zhang, Meenhard Herlyn, Katharina Glatz, Heinz Läubli, Kirsten D. Mertz, Peter Petzelbauer, Thomas Wiesner, Markus Hartl, Winfried F. Pickl, Rajasekharan Somasundaram, Peter Steinberger, Stephan N. Wagner
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
The regulation of tumor inflammation is incompletely understood and the role of B cells is unclear. Here, the authors show that a specific subtype of B cells is induced in melanoma and required to recruit T lymphocytes and elicit inflammation.
Externí odkaz:
https://doaj.org/article/bb7a13c9ab124182a8b518e472ddcec1