Zobrazeno 1 - 10
of 82
pro vyhledávání: '"Katharina Gerlach"'
miRNA142-3p targets Tet2 and impairs Treg differentiation and stability in models of type 1 diabetes
Autor:
Martin G. Scherm, Isabelle Serr, Adam M. Zahm, Jonathan Schug, Saverio Bellusci, Rossella Manfredini, Victoria K. Salb, Katharina Gerlach, Benno Weigmann, Anette-Gabriele Ziegler, Klaus H. Kaestner, Carolin Daniel
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
miRNA142-3p and Tet2 are separately known to regulate Treg. Here the authors show that miRNA142-3p targets Tet2 and by this opposes Treg differentiation in autoimmune diabetes.
Externí odkaz:
https://doaj.org/article/224be2193f454379b9efe6527272f625
Autor:
Sonja Reißig, Yilang Tang, Alexei Nikolaev, Katharina Gerlach, Christine Wolf, Kathrin Davari, Christian Gallus, Joumana Masri, Ilgiz A. Mufazalov, Markus F. Neurath, F. Thomas Wunderlich, Jörn M. Schattenberg, Peter R. Galle, Benno Weigmann, Ari Waisman, Elke Glasmacher, Nadine Hövelmeyer
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
Bcl-3 modulates effector T cell responses, but the importance of Bcl-3 in T regulatory cells and autoimmunity is not clear. Here the authors show that Bcl-3 impedes NF-κB DNA binding to alter T regulatory cell development and function, causing spont
Externí odkaz:
https://doaj.org/article/87d328bf46c940f9b17786b9c4f283ce
Autor:
Marlene Steiner, Lucas Schneider, Jasmin Yillah, Katharina Gerlach, Olga N Kuvardina, Annekarin Meyer, Alisa Maring, Halvard Bonig, Erhard Seifried, Martin Zörnig, Jörn Lausen
Publikováno v:
PLoS ONE, Vol 14, Iss 1, p e0210515 (2019)
During erythropoiesis, haematopoietic stem cells (HSCs) differentiate in successive steps of commitment and specification to mature erythrocytes. This differentiation process is controlled by transcription factors that establish stage- and cell type-
Externí odkaz:
https://doaj.org/article/8f1b570e6ee14df5b514f22b221b3b20
Autor:
Uta Rabenhorst, Frederic B. Thalheimer, Katharina Gerlach, Marek Kijonka, Stefanie Böhm, Daniela S. Krause, Franz Vauti, Hans-Henning Arnold, Timm Schroeder, Frank Schnütgen, Harald von Melchner, Michael A. Rieger, Martin Zörnig
Publikováno v:
Cell Reports, Vol 11, Iss 12, Pp 1847-1855 (2015)
The ability of hematopoietic stem cells (HSCs) to self-renew is a prerequisite for the establishment of definitive hematopoiesis and life-long blood regeneration. Here, we report the single-stranded DNA-binding transcriptional regulator far upstream
Externí odkaz:
https://doaj.org/article/c1163f6eebe147a3bd1e930b1679b3f9
Autor:
Katharina, Gerlach, Vanessa, Popp, Stefan, Wirtz, Ragheed, Al-Saifi, Miguel, Gonzalez Acera, Raja, Atreya, Theresa, Dregelies, Michael, Vieth, Stefan, Fichtner-Feigl, Andrew N J, McKenzie, Frank, Rosenbauer, Benno, Weigmann, Markus F, Neurath
Publikováno v:
Journal of Crohn's and Colitis. 16:1893-1910
Background and Aims Colorectal cancer [CRC] is one of the most frequent malignancies, but the molecular mechanisms driving cancer growth are incompletely understood. We characterised the roles of the cytokine IL-9 and Th9 cells in regulating CRC deve
Autor:
Benno Weigmann, Markus F. Neurath, Stefan Rose-John, Raja Atreya, Thomas Gerlach, Alexei Nikolaev, Hans A. Lehr, Carolin Daniel, Katharina Gerlach
PDF file - 112K, expression of cox-2 and VEGF
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18f7ffc9143f0672a60bae47ae4e2a6a
https://doi.org/10.1158/0008-5472.22392668
https://doi.org/10.1158/0008-5472.22392668
Autor:
Benno Weigmann, Markus F. Neurath, Stefan Rose-John, Raja Atreya, Thomas Gerlach, Alexei Nikolaev, Hans A. Lehr, Carolin Daniel, Katharina Gerlach
PDF file - 547K, DSS Colitis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7453ac5f8deb2dde6a7c1dc0c37c0490
https://doi.org/10.1158/0008-5472.22392686.v1
https://doi.org/10.1158/0008-5472.22392686.v1
Autor:
Benno Weigmann, Markus F. Neurath, Stefan Rose-John, Raja Atreya, Thomas Gerlach, Alexei Nikolaev, Hans A. Lehr, Carolin Daniel, Katharina Gerlach
PDF file - 419K, table of patient data for supplementary figures
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::125c20e7a1766b1e907cb63939ad46ed
https://doi.org/10.1158/0008-5472.22392659
https://doi.org/10.1158/0008-5472.22392659
Autor:
Benno Weigmann, Markus F. Neurath, Stefan Rose-John, Raja Atreya, Thomas Gerlach, Alexei Nikolaev, Hans A. Lehr, Carolin Daniel, Katharina Gerlach
PDF file - 106K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71a4812e8f1114a8e42eade42b5a79e1
https://doi.org/10.1158/0008-5472.22392662.v1
https://doi.org/10.1158/0008-5472.22392662.v1
Autor:
Benno Weigmann, Markus F. Neurath, Stefan Rose-John, Raja Atreya, Thomas Gerlach, Alexei Nikolaev, Hans A. Lehr, Carolin Daniel, Katharina Gerlach
PDF file - 559K, expression of IL-11 and IL-22
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::170d87f81d17b00a59e4ce2b840c1d5f
https://doi.org/10.1158/0008-5472.22392677.v1
https://doi.org/10.1158/0008-5472.22392677.v1