Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Katharina F. Bergerhoff"'
Autor:
Martin McLaughlin, Malin Pedersen, Victoria Roulstone, Katharina F. Bergerhoff, Henry G. Smith, Harriet Whittock, Joan N. Kyula, Magnus T. Dillon, Hardev S. Pandha, Richard Vile, Alan A. Melcher, Kevin J. Harrington
Publikováno v:
Molecular Therapy: Oncolytics, Vol 16, Iss , Pp 238-249 (2020)
Reovirus type 3 Dearing (reovirus) is a tumor-selective oncolytic virus currently under evaluation in clinical trials. Here, we report that the therapeutic efficacy of reovirus in head and neck squamous cell cancer can be enhanced by targeting the un
Externí odkaz:
https://doaj.org/article/ea1817def2d74912aacb316306d0be16
Autor:
Kevin J. Harrington, Martin McLaughlin, Alan Melcher, Anguraj Sadanandam, Anna C. Wilkins, Krisha Desai, Elisa Fontana, Chanthirika Ragulan, Galabina Bozhanova, Shane Foo, Radhika R. Patel, James T.E. Paget, Henry G. Smith, Alex Pearson, Emmanuel C. Patin, Eva Crespo-Rodriguez, Harriet Whittock, Malin Pedersen, Katharina F. Bergerhoff, Magnus T. Dillon
Purpose:ATR inhibitors (ATRi) are in early phase clinical trials and have been shown to sensitize to chemotherapy and radiotherapy preclinically. Limited data have been published about the effect of these drugs on the tumor microenvironment.Experimen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4954af3c614c3181d2ace55e502316ce
https://doi.org/10.1158/1078-0432.c.6527228.v1
https://doi.org/10.1158/1078-0432.c.6527228.v1
Autor:
Kevin J. Harrington, Martin McLaughlin, Alan Melcher, Anguraj Sadanandam, Anna C. Wilkins, Krisha Desai, Elisa Fontana, Chanthirika Ragulan, Galabina Bozhanova, Shane Foo, Radhika R. Patel, James T.E. Paget, Henry G. Smith, Alex Pearson, Emmanuel C. Patin, Eva Crespo-Rodriguez, Harriet Whittock, Malin Pedersen, Katharina F. Bergerhoff, Magnus T. Dillon
Supplementary figures and tables
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e78d734f34504452c9609a08573d068
https://doi.org/10.1158/1078-0432.22469357
https://doi.org/10.1158/1078-0432.22469357
Autor:
Andrew J. Hayes, Kevin J. Harrington, Khin Thway, Alan Melcher, Aadil Khan, Magnus T. Dillon, James T. Paget, Katharina F. Bergerhoff, Radhika R. Patel, Martin McLaughlin, Joan N. Kyula-Currie, Victoria Roulstone, David Mansfield, Henry G. Smith
Purpose:The prevention and treatment of metastatic sarcoma are areas of significant unmet need. Immune checkpoint inhibitor monotherapy has shown little activity in sarcoma and there is great interest in identifying novel treatment combinations that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a346e3b40675453b78bd87196e92d1ba
https://doi.org/10.1158/1078-0432.c.6528191.v1
https://doi.org/10.1158/1078-0432.c.6528191.v1
Autor:
Andrew J. Hayes, Kevin J. Harrington, Khin Thway, Alan Melcher, Aadil Khan, Magnus T. Dillon, James T. Paget, Katharina F. Bergerhoff, Radhika R. Patel, Martin McLaughlin, Joan N. Kyula-Currie, Victoria Roulstone, David Mansfield, Henry G. Smith
Supplementary tables and figures
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::542cb332a1bc5ef6846ca968def963b1
https://doi.org/10.1158/1078-0432.22472303.v1
https://doi.org/10.1158/1078-0432.22472303.v1
Autor:
Joan Kyula-Currie, Andrew J. Hayes, Radhika R. Patel, Khin Thway, Katharina F. Bergerhoff, James T. Paget, Victoria Roulstone, Martin McLaughlin, Henry G. Smith, Alan Melcher, Kevin J. Harrington, Aadil A. Khan, Magnus T. Dillon, David Mansfield
Publikováno v:
Clinical Cancer Research. 25:3443-3454
Purpose: The prevention and treatment of metastatic sarcoma are areas of significant unmet need. Immune checkpoint inhibitor monotherapy has shown little activity in sarcoma and there is great interest in identifying novel treatment combinations that
Autor:
Syed Haider, Robert S. Coffin, Eva Crespo-Rodriguez, Khin Thway, Richard Buus, Alan Melcher, Richard G. Vile, Harriet Whittock, Emmanuel C Patin, Galabina Bozhanova, Kate Newbold, Dae Kim, Katharina F. Bergerhoff, Malin Pedersen, Gareth Muirhead, Martin McLaughlin, Shane Foo, Kevin J. Harrington
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss 2 (2020)
Journal for Immunotherapy of Cancer
Journal for Immunotherapy of Cancer
BackgroundThe aggressive clinical behavior of poorly differentiated and anaplastic thyroid cancers (PDTC and ATC) has proven challenging to treat, and survival beyond a few months from diagnosis is rare. Although 30%–60% of these tumors contain mut
Autor:
Magnus T, Dillon, Katharina F, Bergerhoff, Malin, Pedersen, Harriet, Whittock, Eva, Crespo-Rodriguez, Emmanuel C, Patin, Alex, Pearson, Henry G, Smith, James T E, Paget, Radhika R, Patel, Shane, Foo, Galabina, Bozhanova, Chanthirika, Ragulan, Elisa, Fontana, Krisha, Desai, Anna C, Wilkins, Anguraj, Sadanandam, Alan, Melcher, Martin, McLaughlin, Kevin J, Harrington
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 25(11)
PURPOSE: ATR inhibitors (ATRi) are in early phase clinical trials and have been shown to sensitise to chemotherapy and radiotherapy preclinically. Limited data have been published about the effect of these drugs on the tumor microenvironment. EXPERIM
Autor:
J. Kyula, Katharina F. Bergerhoff, Henry G. Smith, Malin Pedersen, M. Mclaughlin, A. Melcher, K. Harrington, V. Roulstone
Publikováno v:
ESMO Open. 3:A239-A240
Introduction Oncolytic viruses are able to enter and selectively replicate in cancer cells. These self-propagating agents kill through multiple mechanisms and have the potential to promote anti-tumour immune responses. Reovirus strain type 3 Dearing
Autor:
Malin Pedersen, James Campbell, K.J. Harrington, Katharina F. Bergerhoff, James T. Paget, Anna Wilkins, Galabina Bozhanova, Henry G. Smith, Emmanuel C Patin, Harriet Whittock, Radhika Patel, Anguraj Sadanandam, Shane Foo, Elisa Fontana, Magnus T. Dillon, Chanthirika Ragulan, Alan Melcher, Martin McLaughlin
Publikováno v:
Annals of Oncology. 29:viii655