Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Katharina Ehrhardt"'
Autor:
Karène Urgin, Mouhamad Jida, Katharina Ehrhardt, Tobias Müller, Michael Lanzer, Louis Maes, Mourad Elhabiri, Elisabeth Davioud-Charvet
Publikováno v:
Molecules, Vol 22, Iss 1, p 161 (2017)
With the aim of increasing the structural diversity on the early antimalarial drug plasmodione, an efficient and versatile procedure to prepare a series of biaryl- and N-arylalkylamines as plasmodione analogues is described. Using the naturally occur
Externí odkaz:
https://doaj.org/article/53e798cd1fa64668a359e62aaa178e5c
Autor:
Tiffany Bouchery, Gaelle Dénécé, Tarik Attout, Katharina Ehrhardt, Nathaly Lhermitte-Vallarino, Muriel Hachet-Haas, Jean Luc Galzi, Emilie Brotin, Françoise Bachelerie, Laurent Gavotte, Catherine Moulia, Odile Bain, Coralie Martin
Publikováno v:
PLoS ONE, Vol 7, Iss 4, p e34971 (2012)
Litomosoides sigmodontis is a cause of filarial infection in rodents. Once infective larvae overcome the skin barrier, they enter the lymphatic system and then settle in the pleural cavity, causing soft tissue infection. The outcome of infection depe
Externí odkaz:
https://doaj.org/article/4133614462634718bd0911e063939591
Autor:
Jeremy Boilevin, David Lee Williams, Mouhamad Jida, Katharina Ehrhardt, Elisabeth Davioud-Charvet, Michael Lanzer, Elena Cesar Rodo, Liwen Feng, Don Antoine Lanfranchi, Max Bielitza
Publikováno v:
European Journal of Organic Chemistry. 2016:1982-1993
A platform of synthetic methodologies has been established to access a focused library of polysubstituted 3-benzylmenadione derivatives functionalized on the aromatic ring of the naphthoquinone core. Two main routes were explored: 1) The naphthol rou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::59f7e15f3e13043a8ff8cf847a948218
https://doi.org/10.1002/ejoc.201600144
https://doi.org/10.1002/ejoc.201600144
Autor:
Liwen, Feng, Don Antoine, Lanfranchi, Leandro, Cotos, Elena, Cesar-Rodo, Katharina, Ehrhardt, Alice-Anne, Goetz, Herbert, Zimmermann, François, Fenaille, Stephanie A, Blandin, Elisabeth, Davioud-Charvet
Publikováno v:
Organicbiomolecular chemistry. 16(15)
Malaria is a tropical parasitic disease threatening populations in tropical and sub-tropical areas. Resistance to antimalarial drugs has spread all over the world in the past 50 years, thus new drugs are urgently needed. Plasmodione (benzylmenadione
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::06955dcd5449c0fbd2b622576e3db826
https://pubmed.ncbi.nlm.nih.gov/29542786
https://pubmed.ncbi.nlm.nih.gov/29542786
Autor:
Don Antoine Lanfranchi, Herbert Zimmermann, Elisabeth Davioud-Charvet, Katharina Ehrhardt, François Fenaille, Leandro Cotos, Liwen Feng, Elena Cesar-Rodo, Stéphanie Blandin, Alice-Anne Goetz
Publikováno v:
Organic and Biomolecular Chemistry
Organic and Biomolecular Chemistry, Royal Society of Chemistry, 2018, 16, pp.2647-2665. ⟨10.1039/C8OB00227D⟩
Organic & Biomolecular Chemistry
Organic and Biomolecular Chemistry, Royal Society of Chemistry, 2018, 16, pp.2647-2665. ⟨10.1039/C8OB00227D⟩
Organic & Biomolecular Chemistry
Malaria is a tropical parasitic disease threatening populations in tropical and sub-tropical areas. Resistance to antimalarial drugs has spread all over the world in the past 50 years, thus new drugs are urgently needed. Plasmodione (benzylmenadione
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8297c848bed64d4575fd2b9b2ee3c88c
https://hal.archives-ouvertes.fr/hal-02161631
https://hal.archives-ouvertes.fr/hal-02161631
Autor:
Valentina Gallo, Elisabeth Davioud-Charvet, Katja Becker, Katharina Ehrhardt, Laure Johann, Don Antoine Lanfranchi, David L. Williams, Mourad Elhabiri, Max Bielitza, Esther Jortzik, Franziska Mohring, Paolo Arese, Didier Belorgey, Evelin Schwarzer
Publikováno v:
Antioxidants & Redox Signaling
Aims: Early phagocytosis of glucose-6-phosphate dehydrogenase (G6PD)-deficient erythrocytes parasitized by Plasmodium falciparum were shown to protect G6PD-deficient populations from severe malaria. Here, we investigated the mechanism of a novel anti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7221bb64410be75036676ed77b6a67ea
https://doi.org/10.1089/ars.2014.6047
https://doi.org/10.1089/ars.2014.6047
Autor:
Aurelia Geyer, Michael Lanzer, Cecilia P. Sanchez, Mouhamad Jida, Elisabeth Davioud-Charvet, Karène Urgin, Saravanan Mounien, Katharina Ehrhardt, Mourad Elhabiri
Publikováno v:
ACS Infectious Diseases
ACS Infectious Diseases, American Chemical Society, 2017, 3, pp.119-131. ⟨10.1021/acsinfecdis.5b00141⟩
ACS Infectious Diseases, American Chemical Society, 2017, 3, pp.119-131. ⟨10.1021/acsinfecdis.5b00141⟩
Mutational changes in the Plasmodium falciparum chloroquine resistance transporter (PfCRT) have been associated with differential responses to a wide spectrum of biologically active compounds including current and former quinoline and quinoline-like
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::811fb92cf68f303ddfbbcb0b19b270f5
https://pubmed.ncbi.nlm.nih.gov/28183182
https://pubmed.ncbi.nlm.nih.gov/28183182
Autor:
Tobias Müller, Karène Urgin, Katharina Ehrhardt, Mourad Elhabiri, Louis Maes, Mouhamad Jida, Michael Lanzer, Elisabeth Davioud-Charvet
Publikováno v:
Molecules, Vol 22, Iss 1, p 161 (2017)
Molecules : A Journal of Synthetic Chemistry and Natural Product Chemistry
Molecules
Molecules, MDPI, 2017, 22, pp.1-32. ⟨10.3390/molecules22010161⟩
Molecules; Volume 22; Issue 1; Pages: 161
Molecules: a journal of synthetic chemistry and natural product chemistry
Molecules : A Journal of Synthetic Chemistry and Natural Product Chemistry
Molecules
Molecules, MDPI, 2017, 22, pp.1-32. ⟨10.3390/molecules22010161⟩
Molecules; Volume 22; Issue 1; Pages: 161
Molecules: a journal of synthetic chemistry and natural product chemistry
With the aim of increasing the structural diversity on the early antimalarial drug plasmodione, an efficient and versatile procedure to prepare a series of biaryl- and N-arylalkylamines as plasmodione analogues is described. Using the naturally occur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d94a01bc052f06f522d7363063eb7a3d
http://www.mdpi.com/1420-3049/22/1/161
http://www.mdpi.com/1420-3049/22/1/161
Autor:
Katharina Ehrhardt, Marcel Deponte, Akhil B. Vaidya, Michael Lanzer, Hangjun Ke, Elisabeth Davioud-Charvet
Publikováno v:
Antimicrobial Agents and Chemotherapy. 57:2114-2120
Methylene blue and a series of recently developed 1,4-naphthoquinones, including 3-[4-(substituted)benzyl]-menadiones, are potent antimalarial agents in vitro and in vivo . The activity of these structurally diverse compounds against the human malari
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da64e3510f4a3b90e6fd77637a2a456e
https://doi.org/10.1128/aac.02248-12
https://doi.org/10.1128/aac.02248-12
Autor:
Valentina Gallo, Katharina Ehrhardt, Alice-Anne Goetz, Paolo Arese, Elisabeth Davioud-Charvet, Bruno Pradines, Denyse Bagrel, Tzvetomira Tzanova, Christiane Deregnaucourt, Stéphanie Blandin, Sophie H. Adjalley, Michael Lanzer
Publikováno v:
Antimicrobial Agents and Chemotherapy
Antimicrobial Agents and Chemotherapy, American Society for Microbiology, 2016, 60 (9), pp.5146-5158. ⟨10.1128/AAC.02975-15⟩
Antimicrobial Agents and Chemotherapy, 2016, 60 (9), pp.5146-5158. ⟨10.1128/AAC.02975-15⟩
Antimicrobial Agents and Chemotherapy, American Society for Microbiology, 2016, 60 (9), pp.5146-5158. ⟨10.1128/AAC.02975-15⟩
Antimicrobial Agents and Chemotherapy, 2016, 60 (9), pp.5146-5158. ⟨10.1128/AAC.02975-15⟩
Previously, we presented the chemical design of a promising series of antimalarial agents, 3-[substituted-benzyl]-menadiones, with potent in vitro and in vivo activities. Ongoing studies on the mode of action of antimalarial 3-[substituted-benzyl]-me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bcec4db27ad577dcbb3fadd95081caaa
https://europepmc.org/articles/PMC4997830/
https://europepmc.org/articles/PMC4997830/