Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Katharina E. J. Jungnickel"'
Autor:
Florian Gabriel, Lea Spriestersbach, Antonia Fuhrmann, Katharina E. J. Jungnickel, Siavash Mostafavi, Els Pardon, Jan Steyaert, Christian Löw
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract Thiamine (vitamin B1) functions as an essential coenzyme in cells. Humans and other mammals cannot synthesise this vitamin de novo and thus have to take it up from their diet. Eventually, every cell needs to import thiamine across its plasma
Externí odkaz:
https://doaj.org/article/927abfb529fa4d22bc7ff884136bde30
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
Cationic amino acid transporters (CATs) belong to the physiologically important solute carrier (SLC) 7 family. Here, the authors present the structure of the mammalian CAT transporter homologue Geobacillus kaustophilus GkApcT, which reveals how argin
Externí odkaz:
https://doaj.org/article/2c65c0d0f0794387bf5392c87870ed24
Autor:
Kenneth R. Beyerlein, Dennis Dierksmeyer, Valerio Mariani, Manuela Kuhn, Iosifina Sarrou, Angelica Ottaviano, Salah Awel, Juraj Knoska, Silje Fuglerud, Olof Jönsson, Stephan Stern, Max O. Wiedorn, Oleksandr Yefanov, Luigi Adriano, Richard Bean, Anja Burkhardt, Pontus Fischer, Michael Heymann, Daniel A. Horke, Katharina E. J. Jungnickel, Elena Kovaleva, Olga Lorbeer, Markus Metz, Jan Meyer, Andrew Morgan, Kanupriya Pande, Saravanan Panneerselvam, Carolin Seuring, Aleksandra Tolstikova, Julia Lieske, Steve Aplin, Manfred Roessle, Thomas A. White, Henry N. Chapman, Alke Meents, Dominik Oberthuer
Publikováno v:
IUCrJ, Vol 4, Iss 6, Pp 769-777 (2017)
Unravelling the interaction of biological macromolecules with ligands and substrates at high spatial and temporal resolution remains a major challenge in structural biology. The development of serial crystallography methods at X-ray free-electron las
Externí odkaz:
https://doaj.org/article/e490cd1b81b944869066336aa07f9314
Publikováno v:
Nature Communications
Nature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
Nature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
Amino acids play essential roles in cell biology as regulators of metabolic pathways. Arginine in particular is a major signalling molecule inside the cell, being a precursor for both l-ornithine and nitric oxide (NO) synthesis and a key regulator of
Plasticity of the binding pocket in peptide transporters underpins promiscuous substrate recognition
Autor:
Vadim Kotov, Maxime Killer, Katharina E. J. Jungnickel, Jian Lei, Giada Finocchio, Josi Steinke, Kim Bartels, Jan Strauss, Florine Dupeux, Anne-Sophie Humm, Irina Cornaciu, José A. Márquez, Els Pardon, Jan Steyaert, Christian Löw
Publikováno v:
bioRxiv
SummaryProton-coupled oligopeptide transporters (POTs) are promiscuous transporters of the Major Facilitator Superfamily, that constitute the main route of entry for a wide range of dietary peptides and orally administrated peptidomimetic drugs. Give
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d35edbd8c2b02cffb9fe5906f251a8c6