Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Katharina Debowski"'
Autor:
Stoyan Petkov, Tobias Kahland, Orr Shomroni, Thomas Lingner, Gabriela Salinas, Sigrid Fuchs, Katharina Debowski, Rüdiger Behr
Publikováno v:
PLoS ONE, Vol 13, Iss 9, p e0204580 (2018)
Following a certain type-specific number of mitotic divisions, terminally differentiated cells undergo proliferative senescence, thwarting efforts to expand different cell populations in vitro for the needs of scientific research or medical therapies
Externí odkaz:
https://doaj.org/article/0469f850feed43149eb586dead3c3867
Autor:
Taruna Anand, Thirumala R Talluri, Dharmendra Kumar, Wiebke Garrels, Ayan Mukherjee, Katharina Debowski, Rüdiger Behr, Wilfried A Kues
Publikováno v:
PLoS ONE, Vol 11, Iss 6, p e0157570 (2016)
Curative approaches for eye cataracts and other eye abnormalities, such as myopia and hyperopia currently suffer from a lack of appropriate models. Here, we present a new approach for in vitro growth of lentoid bodies from induced pluripotent stem (i
Externí odkaz:
https://doaj.org/article/1d3fe18dc9fc4a6ba7b114e6169231e6
Autor:
Katharina Debowski, Rita Warthemann, Jana Lentes, Gabriela Salinas-Riester, Ralf Dressel, Daniel Langenstroth, Jörg Gromoll, Erika Sasaki, Rüdiger Behr
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0118424 (2015)
Groundbreaking studies showed that differentiated somatic cells of mouse and human origin could be reverted to a stable pluripotent state by the ectopic expression of only four proteins. The resulting pluripotent cells, called induced pluripotent ste
Externí odkaz:
https://doaj.org/article/1c64459cbf0748a2a49bd7ac1c87b915
Autor:
Anke Miriam Krähling, Luis Alvarez, Katharina Debowski, Qui Van, Monika Gunkel, Stephan Irsen, Ashraf Al-Amoudi, Timo Strünker, Elisabeth Kremmer, Eberhard Krause, Ingo Voigt, Simone Wörtge, Ari Waisman, Ingo Weyand, Reinhard Seifert, Ulrich Benjamin Kaupp, Dagmar Wachten
Publikováno v:
PLoS Genetics, Vol 9, Iss 12, p e1003960 (2013)
The second messengers cAMP and cGMP activate their target proteins by binding to a conserved cyclic nucleotide-binding domain (CNBD). Here, we identify and characterize an entirely novel CNBD-containing protein called CRIS (cyclic nucleotide receptor
Externí odkaz:
https://doaj.org/article/749b7041ed2a48a786e94e940f61e4b0
Autor:
Gabriela Salinas, Rüdiger Behr, Sigrid Fuchs, Orr Shomroni, Katharina Debowski, Tobias Kahland, Stoyan Petkov, Thomas Lingner
Publikováno v:
PLoS ONE
PLoS ONE, Vol 13, Iss 9, p e0204580 (2018)
PLoS ONE, Vol 13, Iss 9, p e0204580 (2018)
Following a certain type-specific number of mitotic divisions, terminally differentiated cells undergo proliferative senescence, thwarting efforts to expand different cell populations in vitro for the needs of scientific research or medical therapies
Autor:
Wiebke Garrels, Heiner Niemann, Dharmendra Kumar, Rüdiger Behr, Silke Glage, Katharina Debowski, Wilfried A. Kues, Zoltán Ivics, Thirumala Rao Talluri
Publikováno v:
Cellular Reprogramming. 17:131-140
Induced pluripotent stem cells (iPSCs) are a seminal breakthrough in stem cell research and are promising tools for advanced regenerative therapies in humans and reproductive biotechnology in farm animals. iPSCs are particularly valuable in species i
Autor:
Katharina Debowski, Ralf Dressel, Sigrid Fuchs, Rüdiger Behr, Gabriela Salinas-Riester, Erika Sasaki, Charis Drummer, Jana Lentes, Maren Cors, Thomas Lingner
Publikováno v:
Scientific Reports
Embryonic stem cells (ESCs) are useful for the study of embryonic development. However, since research on naturally conceived human embryos is limited, non-human primate (NHP) embryos and NHP ESCs represent an excellent alternative to the correspondi
Publikováno v:
Molecular Human Reproduction
Octamer-binding protein 4 (OCT4) is a key player in pluripotent embryonic stem (ES) cells and is essential for the generation of induced pluripotent stem cells. Recently, several reports indicated the spontaneous recovery of pluripotency in cultured
Autor:
K. Eildermann, Sabine Kliesch, Stefan Schlatt, N. Aeckerle, Joerg Gromoll, M. Heistermann, Jens Ehmcke, H. Christiansen, Katharina Debowski, Maren Godmann, S. Schweyer, Martin Bergmann, R. Behr
Publikováno v:
Cells Tissues Organs. 196:206-220
SALL4 (sal-like protein 4) is a pluripotency transcription fac- tor, which is highly expressed in embryonic stem (ES) cells and which is essential for mo use preimplantation develop- ment. In adult mouse organs, Sall4 mRNA is highly expressed in the
Autor:
Rüdiger Behr, Wilfried A. Kues, Talluri Thirumala Rao, Heiner Niemann, Dharmendra Kumar, Wiebke Garrels, Katharina Debowski, Silke Glage
Publikováno v:
Reproduction Abstracts.