Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Katharina Billian-Frey"'
Autor:
Jamie Frankish, Debayan Mukherjee, Erminia Romano, Katharina Billian-Frey, Matthias Schröder, Karl Heinonen, Christian Merz, Mauricio Redondo Müller, Christian Gieffers, Oliver Hill, Meinolf Thiemann, Jamie Honeychurch, Tim Illidge, Jaromir Sykora
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionThe ability to modulate and enhance the anti-tumor immune responses is critical in developing novel therapies in cancer. The Tumor Necrosis Factor (TNF) Receptor Super Family (TNFRSF) are potentially excellent targets for modulation which
Externí odkaz:
https://doaj.org/article/3a2c8f98856e4fc4a7c38804f359c93f
Autor:
David M. Richards, Viola Marschall, Katharina Billian-Frey, Karl Heinonen, Christian Merz, Mauricio Redondo Müller, Julian P. Sefrin, Matthias Schröder, Jaromir Sykora, Harald Fricke, Oliver Hill, Christian Gieffers, Meinolf Thiemann
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 7, Iss 1, Pp 1-13 (2019)
Abstract Background Glucocorticoid-induced TNFR-related protein (TNFRSF18, GITR, CD357), expressed by T cells, and its ligand (TNFSF18, GITRL), expressed by myeloid populations, provide co-stimulatory signals that boost T cell activity. Due to the im
Externí odkaz:
https://doaj.org/article/04921d3723f8400dab5dcc210d3292d0
Autor:
Oliver Hill, Katharina Billian-Frey, Matthias Schroeder, Christian Gieffers, Jaromir Sykora, Meinolf Thiemann, Jamie Frankish, Karl Heinonen, Mauricio Redondo-Mueller
Publikováno v:
Cancer Research. 81:1587-1587
CD40 ligand is a member of the TNF superfamily (TNF-SF) and a key regulator of the immune system. Its cognate receptor CD40 is expressed on antigen-presenting cells and on many tumor types, and has emerged as an attractive target for immunological ca
Autor:
Oliver Hill, Christian Merz, Meinolf Thiemann, Christian Gieffers, David M. Richards, Julian P. Sefrin, Katharina Billian-Frey, Mauricio Redondo Müller, Karl Heinonen, Harald Fricke, Jaromir Sykora, Matthias Schröder, Viola Marschall
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 7, Iss 1, Pp 1-13 (2019)
Journal for Immunotherapy of Cancer
Journal for Immunotherapy of Cancer
Background Glucocorticoid-induced TNFR-related protein (TNFRSF18, GITR, CD357), expressed by T cells, and its ligand (TNFSF18, GITRL), expressed by myeloid populations, provide co-stimulatory signals that boost T cell activity. Due to the important r
Autor:
Mauricio Redondo Müller, Katharina Billian-Frey, Matthias Schröder, Jaromir Sykora, David M. Richards, Christian Merz, Oliver Hill, Meinolf Thiemann, Julian P. Sefrin, Christian Gieffers, Karl Heinonen
Publikováno v:
Cancer Research. 80:1076-1076
TNF Receptor Superfamily members (TNF-R-SF), including CD40, are key regulators of the immune system and have been immunotherapeutic targets for over 20 years. CD40 signaling serves as an important co-stimulatory signal for antigen-presenting cells (
Autor:
Meinolf Thiemann, Oliver Hill, Jaromir Sykora, Christian Gieffers, Karl Heinonen, Christian Merz, Julian P. Sefrin, Katharina Billian-Frey, David M. Richards, Mauricio Redondo Müller, Matthias Schröder
Publikováno v:
Cancer Research. 80:4460-4460
CD40 ligand is a member of the TNF superfamily and a key regulator of the immune system. Its cognate receptor CD40 is expressed on antigen-presenting cells and on many tumor types, and has emerged as an attractive target for immunological cancer trea
Autor:
Katharina Billian-Frey, David M. Richards, Meinolf Thiemann, Matthias Schröder, Viola Marschall, Harald Fricke, Christian Gieffers, Julian P. Sefrin, Karl Heinonen, Mauricio Redondo Müller, Christian Merz, Jaromir Sykora, Hill Oliver
Publikováno v:
Cancer Research. 79:5015-5015
CD40 ligand is a member of the TNF superfamily (TNF-SF) and a key regulator of the immune system. Its cognate receptor CD40 is expressed on antigen-presenting cells and on many tumor types, and has emerged as an attractive target for immunological ca
Autor:
Christian Gieffers, Mauricio Redondo Müller, Jaromir Sykora, Karl Heinonen, Harald Fricke, Meinolf Thiemann, Katharina Billian-Frey, Christian Merz, Julian P. Sefrin, Matthias Schröder, David M. Richards, Oliver Hill, Viola Marschall
Publikováno v:
Cancer Research. 79:4845-4845
Agonistic stimulation of TNFRSF members like CD27 is a promising strategy to boost anti-tumor responses. Although antibodies are effective inhibitors of signaling, they have shown minimal agonistic activity due to their limited binding domains, flexi
Autor:
Viola Marshall, Meinolf Thiemann, Mauricio Redondo-Müller, Katharina Billian-Frey, Julian P. Sefrin, David M. Richards, Jaromir Sykora, Christian Gieffers, Matthias Schröder, Karl Heinonen, Christian Merz, Oliver Hill
Publikováno v:
Cancer Research. 79:4143-4143
Glucocorticoid-induced TNFR-related protein (GITR, TNFRSF18, CD357), a TNFR-SF member, is a co-stimulatory receptor that increases anti-tumor T cell activation. Based on Apogenix TNFR-SF agonist HERA-technology, we created a fully human hexavalent GI