Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Katharina, Sobotta"'
Publikováno v:
Pathogens, Vol 11, Iss 12, p 1422 (2022)
Despite the high prevalence of C. burnetii in dairy herds and continuous shedding via milk by chronically infected cows, bovine milk is not recognized as a relevant source of human Q fever. We hypothesized that the bovine mammary gland epithelial cel
Externí odkaz:
https://doaj.org/article/f05541a505bb4abd9469698e19b3d2aa
Autor:
Katharina Sobotta, Katharina Bonkowski, Elisabeth Liebler-Tenorio, Pierre Germon, Pascal Rainard, Nina Hambruch, Christiane Pfarrer, Ilse D. Jacobsen, Christian Menge
Publikováno v:
Veterinary Research, Vol 48, Iss 1, Pp 1-15 (2017)
Abstract Ruminants are the main source of human infections with the obligate intracellular bacterium Coxiella (C.) burnetii. Infected animals shed high numbers of C. burnetii by milk, feces, and birth products. In goats, shedding by the latter route
Externí odkaz:
https://doaj.org/article/c388ce205e00405f8bfb49a389ea6e08
Autor:
Inaya Hayek, Fabian Fischer, Jan Schulze-Luehrmann, Katja Dettmer, Katharina Sobotta, Valentin Schatz, Lisa Kohl, Katharina Boden, Roland Lang, Peter J. Oefner, Stefan Wirtz, Jonathan Jantsch, Anja Lührmann
Publikováno v:
Cell Reports, Vol 26, Iss 13, Pp 3502-3510.e6 (2019)
Summary: In hypoxic and inflamed tissues, oxygen (O2)-dependent antimicrobial defenses are impaired due to a shortage of O2. To gain insight into the mechanisms that control bacterial infection under hypoxic conditions, we infected macrophages with t
Externí odkaz:
https://doaj.org/article/7d1d9428a7874011ac639ef6e05994c3
Autor:
Nancy, Unger, Simone, Eiserloh, Frauke, Nowak, Sara, Zuchantke, Elisabeth, Liebler-Tenorio, Katharina, Sobotta, Christiane, Schnee, Christian, Berens, Ute, Neugebauer
Publikováno v:
Analytical chemistry. 94(12)
The life cycle of intracellular pathogens is often complex and can include different morphoforms. Treatment of intracellular infections and unperturbed studying of the pathogen inside the host cell are frequently challenging. Here, we present a Raman
Autor:
Nancy Unger, Simone Eiserloh, Frauke Nowak, Sara Zuchantke, Elisabeth Liebler-Tenorio, Katharina Sobotta, Christiane Schnee, Christian Berens, Ute Neugebauer
Publikováno v:
Analytical Chemistry. 94:4988-4996
Autor:
Katharina Sobotta, Kirstin Hillarius, Pablo H. Jiménez, Katharina Kerner, Carsten Heydel, Christian Menge
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 7 (2018)
Most human Q fever infections originate from small ruminants. By contrast, highly prevalent shedding of Coxiella (C.) burnetii by bovine milk rarely results in human disease. We hypothesized that primary bovine and human monocyte-derived macrophages
Externí odkaz:
https://doaj.org/article/4b6e21cf88c54ffc9dfb08cc1cb1e61a
Publikováno v:
Pathogens (Basel, Switzerland). 11(12)
Despite the high prevalence of
Publikováno v:
Access Microbiology
Small-colony variants are slow-growing subpopulations of bacteria known to be involved in latent or recurrent infections, especially in deep-seated foci. Their atypical growth in small colonies can hamper prompt and correct identification in clinical
Autor:
Peter J. Oefner, Katja Dettmer, Inaya Hayek, Valentin Schatz, Katharina Boden, Stefan Wirtz, Jan Schulze-Luehrmann, Fabian Fischer, Jonathan Jantsch, Katharina Sobotta, Lisa Kohl, Anja Lührmann, Roland Lang
Publikováno v:
Cell Reports, Vol 26, Iss 13, Pp 3502-3510.e6 (2019)
Summary: In hypoxic and inflamed tissues, oxygen (O2)-dependent antimicrobial defenses are impaired due to a shortage of O2. To gain insight into the mechanisms that control bacterial infection under hypoxic conditions, we infected macrophages with t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb89c78c07fbafaa7947fb769638adcb
Autor:
Anja Lührmann, Leonie Klingenbeck, Katharina Sobotta, Jan Schulze-Luehrmann, Vítor Borges, João Paulo Gomes, Christian Menge, Stephanie Bisle, Carsten Heydel
Publikováno v:
Virulence. 7:400-412
Coxiella burnetii is an obligate intracellular bacterium that causes Query (Q) fever, a zoonotic disease. It requires a functional type IV secretion system (T4SS) which translocate bacterial effector proteins into the host cell cytoplasm and thereby