Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Katharina, Schipany"'
Autor:
Norbert Kraut, Darryl B. McConnell, Mark Pearson, Timothy P. Heffernan, Mark Petronczki, Jurgen Moll, Rachel L. Mendes, Jonathan C. O'Connell, Christopher P. Vellano, Simone Lieb, Katharina Schipany, Franziska Schachinger, Nikolai Pototschnig, Jark Böttcher, Jessica L. Teh, Szu-Chin Fu, Andreas Zoephel, Tobias Wunberg, Christiane Kofink, Thomas Gerstberger, Peter Ettmayer, Dana-Adriana Botesteanu, Klaus Rumpel, Heribert Arnhof, Francesca Trapani, Dirk Kessler, Michael P. Sanderson, Joseph R. Marszalek, Daniel Gerlach, Fabio Savarese, Juergen Ramharter, Michael Gmachl, Marco H. Hofmann
Supplementary Data, Table S1, S3, S6, S8, S10-S13
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3b265e4961eac4720f5366a19b7c1c2
https://doi.org/10.1158/2159-8290.22535216
https://doi.org/10.1158/2159-8290.22535216
Autor:
Norbert Kraut, Darryl B. McConnell, Mark Pearson, Timothy P. Heffernan, Mark Petronczki, Jurgen Moll, Rachel L. Mendes, Jonathan C. O'Connell, Christopher P. Vellano, Simone Lieb, Katharina Schipany, Franziska Schachinger, Nikolai Pototschnig, Jark Böttcher, Jessica L. Teh, Szu-Chin Fu, Andreas Zoephel, Tobias Wunberg, Christiane Kofink, Thomas Gerstberger, Peter Ettmayer, Dana-Adriana Botesteanu, Klaus Rumpel, Heribert Arnhof, Francesca Trapani, Dirk Kessler, Michael P. Sanderson, Joseph R. Marszalek, Daniel Gerlach, Fabio Savarese, Juergen Ramharter, Michael Gmachl, Marco H. Hofmann
KRAS is the most frequently mutated driver of pancreatic, colorectal, and non–small cell lung cancers. Direct KRAS blockade has proved challenging, and inhibition of a key downstream effector pathway, the RAF–MEK–ERK cascade, has shown limited
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4207250379f0cc7e1fcd4e873b0d65cb
https://doi.org/10.1158/2159-8290.c.6547790.v1
https://doi.org/10.1158/2159-8290.c.6547790.v1
Autor:
Norbert Kraut, Darryl B. McConnell, Mark Pearson, Timothy P. Heffernan, Mark Petronczki, Jurgen Moll, Rachel L. Mendes, Jonathan C. O'Connell, Christopher P. Vellano, Simone Lieb, Katharina Schipany, Franziska Schachinger, Nikolai Pototschnig, Jark Böttcher, Jessica L. Teh, Szu-Chin Fu, Andreas Zoephel, Tobias Wunberg, Christiane Kofink, Thomas Gerstberger, Peter Ettmayer, Dana-Adriana Botesteanu, Klaus Rumpel, Heribert Arnhof, Francesca Trapani, Dirk Kessler, Michael P. Sanderson, Joseph R. Marszalek, Daniel Gerlach, Fabio Savarese, Juergen Ramharter, Michael Gmachl, Marco H. Hofmann
Supplementary Figures S1-S5
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d96dfb43e0dbbd26e81b12152a9d88c
https://doi.org/10.1158/2159-8290.22535234
https://doi.org/10.1158/2159-8290.22535234
Autor:
Juliane Zantke, Tomoko Ishikawa-Fujiwara, Enrique Arboleda, Claudia Lohs, Katharina Schipany, Natalia Hallay, Andrew D. Straw, Takeshi Todo, Kristin Tessmar-Raible
Publikováno v:
Cell Reports, Vol 5, Iss 1, Pp 99-113 (2013)
Life is controlled by multiple rhythms. Although the interaction of the daily (circadian) clock with environmental stimuli, such as light, is well documented, its relationship to endogenous clocks with other periods is little understood. We establish
Externí odkaz:
https://doaj.org/article/2eabbea9596a425c99336eaec55a2cd7
Autor:
Szu-Chin Fu, Norbert Kraut, Rachel L Mendes, Marco H. Hofmann, Michael Gmachl, Peter Ettmayer, Katharina Schipany, Juergen Ramharter, Joseph R. Marszalek, Michael P. Sanderson, Tobias Wunberg, Fabio Savarese, Mark Petronczki, Timothy P. Heffernan, Thomas Gerstberger, Jark Böttcher, Mark Pearson, Dana-Adriana Botesteanu, Daniel Gerlach, Dirk Kessler, Franziska Schachinger, Klaus Rumpel, Jessica Teh, Jonathan O’Connell, Christiane Kofink, Heribert Arnhof, Simone Lieb, Jürgen Moll, Christopher P. Vellano, Nikolai Pototschnig, Andreas Zoephel, Darryl B. McConnell, Francesca Trapani
Publikováno v:
Cancer discovery. 11(1)
KRAS is the most frequently mutated driver of pancreatic, colorectal, and non–small cell lung cancers. Direct KRAS blockade has proved challenging, and inhibition of a key downstream effector pathway, the RAF–MEK–ERK cascade, has shown limited
Autor:
Margit Rosner, Katharina Schipany, Bharanidharan Shanmugasundaram, Gert Lubec, Markus Hengstschläger
Publikováno v:
Stem Cells International, Vol 2012 (2012)
The existence of stem cells in human amniotic fluid was reported for the first time almost ten years ago. Since this discovery, the knowledge about these cells has increased dramatically. Today, amniotic fluid stem (AFS) cells are widely accepted as
Externí odkaz:
https://doaj.org/article/6a18c723354a4461b2c926d1db829729
Autor:
Andreas Schrenk, Daniela Häring, Silke Fischer, Stefan Kornigg, Alex G. Waterson, Andreas Mantoulidis, Manfred Koegl, Markus Zeeb, Thomas Gerstberger, Mark Pearson, Wolfgang Hela, Andreas Zoephel, Darryl B. McConnell, Michael Gmachl, Bernadette Sharps, Jale Karolyi-Oezguer, Johann Hoffmann, Franziska Moser, Jason Phan, Teresa Gmaschitz, David Covini, Bernhard Wolkerstorfer, Qi Sun, Lyne Lamarre, Gabriella Siszler, Renate Schnitzer, Moriz Mayer, Dirk Kessler, Katharina Schipany, Petr Knesl, Christian Salamon, Peter Greb, Stephen W. Fesik, Andreas Gollner, Yvonne Scherbantin, Silvia Munico-Martinez, Craig M. Goodwin, Roland Kousek, Jörg Rinnenthal, Jiqing Sai, Christoph Peinsipp, Laetitia J. Martin
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance Despite decades of research, no approved drugs have been discovered for KRAS. Recently, a pocket occurring on the surface of the active and inactive form of KRAS was found, but, due to its comparatively shallow, polar nature, this pocket
Publikováno v:
European Journal of Clinical Investigation. 45:415-422
Background The ability of cells to travel long distances in order to form tissues and organs is inherently connected to embryogenesis. The process in which epithelial-like embryonic cells become motile and invasive is termed ‘epithelial-to-mesenchy
Publikováno v:
Stem Cells Translational Medicine. 3:553-559
Summary Because of recent advances, the array of human pluripotent stem cells now contains embryonic stem cells, derived from “surplus” in vitro fertilization embryos or from cloned embryos; induced pluripotent stem cells; and amniotic fluid stem
Publikováno v:
Amino Acids. 44:1233-1240
Of all known ribosomal proteins, the 40S ribosomal protein S6 is by far the most extensively studied. Still, little is known about some basic aspects of S6 regulation including its cell cycle-related expression and localization. Using a flow cytometr