Zobrazeno 1 - 10
of 54
pro vyhledávání: '"Katharina, Lahl"'
Autor:
Hongkui Xiao, Isabel Ulmert, Luisa Bach, Johanna Huber, Hamsa Narasimhan, Ilia Kurochkin, Yinshui Chang, Signe Holst, Urs Mörbe, Lili Zhang, Andreas Schlitzer, Carlos-Filipe Pereira, Barbara U. Schraml, Dirk Baumjohann, Katharina Lahl
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract Conventional dendritic cells (cDC) play key roles in immune induction, but what drives their heterogeneity and functional specialization is still ill-defined. Here we show that cDC-specific deletion of the transcriptional repressor Bcl6 in m
Externí odkaz:
https://doaj.org/article/8ced88913257448eb2779911a6a66c72
Autor:
Kedir Hussen Hamza, Emma Dunér, Isabel Ulmert, Armando Arias, Daniel Sorobetea, Katharina Lahl
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract Viral triggers at the intestinal mucosa can have multiple global effects on intestinal integrity, causing elevated intestinal barrier strength and relative protection from subsequent inflammatory bowel disease (IBD) induction in various mode
Externí odkaz:
https://doaj.org/article/5f477c0aee734c6986fc32b1f6080948
Autor:
Madelene W. Dahlgren, Adam W. Plumb, Kristoffer Niss, Katharina Lahl, Søren Brunak, Bengt Johansson-Lindbom
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Type I interferons (IFNs) are essential for antiviral immunity, appear to represent a key component of mRNA vaccine-adjuvanticity, and correlate with severity of systemic autoimmune disease. Relevant to all, type I IFNs can enhance germinal center (G
Externí odkaz:
https://doaj.org/article/506d2b0c10234ec297ecb6f6a11d3519
Autor:
Konjit Getachew Muleta, Isabel Ulmert, Kedir Hussen Hamza, Sharné van Dijl, Joy Nakawesi, Katharina Lahl
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Rotavirus (RV) infection induces strong adaptive immunity. While protection from reinfection requires humoral immunity, initial clearance of infection depends on cytotoxic CD8 T cells. Type I classical dendritic cells (cDC1) excel at CD8 T cell induc
Externí odkaz:
https://doaj.org/article/e3ad6a89d97b435a8e23e151e0affbd4
Autor:
Zichen Wang, Caroline D. Monteiro, Kathleen M. Jagodnik, Nicolas F. Fernandez, Gregory W. Gundersen, Andrew D. Rouillard, Sherry L. Jenkins, Axel S. Feldmann, Kevin S. Hu, Michael G. McDermott, Qiaonan Duan, Neil R. Clark, Matthew R. Jones, Yan Kou, Troy Goff, Holly Woodland, Fabio M R. Amaral, Gregory L. Szeto, Oliver Fuchs, Sophia M. Schüssler-Fiorenza Rose, Shvetank Sharma, Uwe Schwartz, Xabier Bengoetxea Bausela, Maciej Szymkiewicz, Vasileios Maroulis, Anton Salykin, Carolina M. Barra, Candice D. Kruth, Nicholas J. Bongio, Vaibhav Mathur, Radmila D Todoric, Udi E. Rubin, Apostolos Malatras, Carl T. Fulp, John A. Galindo, Ruta Motiejunaite, Christoph Jüschke, Philip C. Dishuck, Katharina Lahl, Mohieddin Jafari, Sara Aibar, Apostolos Zaravinos, Linda H. Steenhuizen, Lindsey R. Allison, Pablo Gamallo, Fernando de Andres Segura, Tyler Dae Devlin, Vicente Pérez-García, Avi Ma’ayan
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-11 (2016)
A wealth of gene expression data is publicly available, yet is little use without additional human curation. Ma’ayan and colleagues report a crowdsourcing project involving over 70 participants to annotate and analyse thousands of human disease-rel
Externí odkaz:
https://doaj.org/article/a8f2b28d890e4a0e99fc75b9634da8c0
Autor:
null Hans Christian Probst, null Patrizia Stoitzner, null Lukas Amon, null Ronald A. Backer, null Anna Brand, null Jianzhou Chen, null Björn E. Clausen, null Sophie Dieckmann, null Diana Dudziak, null Lukas Heger, null Katrin Hodapp, null Florian Hornsteiner, null Avi‐Hai Hovav, null Lukas Jacobi, null Xingqi Ji, null Nadine Kamenjarin, null Katharina Lahl, null Imran Lahmar, null Jelena Lakus, null Christian H. K. Lehmann, null Daniela Ortner, null Marion Picard, null Maria Paula Roberti, null Lukas Rossnagel, null Yasmin Saba, null Carmen Schalla, null Andreas Schlitzer, null Barbara U. Schraml, null Kristian Schütze, null Anna Seichter, null Kristin Seré, null Athanasios Seretis, null Sieghart Sopper, null Helen Strandt, null Martina M. Sykora, null Hannah Theobald, null Christoph H. Tripp, null Laurence Zitvogel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7453d187edae91b64e1125b64ac40244
https://doi.org/10.1002/eji.202249819/v3/response1
https://doi.org/10.1002/eji.202249819/v3/response1
Autor:
Hans Christian Probst, Patrizia Stoitzner, Lukas Amon, Ronald A. Backer, Anna Brand, Jianzhou Chen, Björn E. Clausen, Sophie Dieckmann, Diana Dudziak, Lukas Heger, Katrin Hodapp, Florian Hornsteiner, Avi‐Hai Hovav, Lukas Jacobi, Xingqi Ji, Nadine Kamenjarin, Katharina Lahl, Imran Lahmar, Jelena Lakus, Christian H. K. Lehmann, Daniela Ortner, Marion Picard, Maria Paula Roberti, Lukas Rossnagel, Yasmin Saba, Carmen Schalla, Andreas Schlitzer, Barbara U. Schraml, Kristian Schütze, Anna Seichter, Kristin Seré, Athanasios Seretis, Sieghart Sopper, Helen Strandt, Martina M. Sykora, Hannah Theobald, Christoph H. Tripp, Laurence Zitvogel
Publikováno v:
European journal of immunologyReferences.
This article is part of the Dendritic Cell Guidelines article series, which provides a collection of state-of-the-art protocols for the preparation, phenotype analysis by flow cytometry, generation, fluorescence microscopy and functional characteriza
Autor:
Hongkui Xiao, Isabel Ulmert, Johanna Huber, Hamsa Narasimhan, Luisa Bach, Ilia Kurochkin, Urs Mörbe, Lili Zhang, Andreas Schlitzer, Filipe Pereira, Barbara U. Schraml, Dirk Baumjohann, Katharina Lahl
Conventional dendritic cells (cDC) play key roles in immune induction, but what drives their heterogeneity and functional specialization is still ill-defined. Here we show that deletion of the transcriptional repressor Bcl6 in murine cDC alters the p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::872b82dc5c79377fe90f831cd69313fb
https://doi.org/10.1101/2022.08.10.503322
https://doi.org/10.1101/2022.08.10.503322
Autor:
Joy Nakawesi, Bengt Johansson-Lindbom, Getachew Muleta Konjit, Dragos-Christian Dasoveanu, Katharina Lahl
Publikováno v:
European Journal of Immunology
Nakawesi, J, Konjit, G M, Dasoveanu, D C, Johansson-Lindbom, B & Lahl, K 2021, ' Rotavirus infection causes mesenteric lymph node hypertrophy independently of type I interferon or TNF-α in mice ', European Journal of Immunology, vol. 51, no. 5, pp. 1143-1152 . https://doi.org/10.1002/eji.202048990
Nakawesi, J, Konjit, G M, Dasoveanu, D C, Johansson-Lindbom, B & Lahl, K 2021, ' Rotavirus infection causes mesenteric lymph node hypertrophy independently of type I interferon or TNF-α in mice ', European Journal of Immunology, vol. 51, no. 5, pp. 1143-1152 . https://doi.org/10.1002/eji.202048990
Lymphoid organ hypertrophy is a characteristic feature of acute infection and is considered to enable efficient induction of adaptive immune responses. Accordingly, oral infection with rotavirus induced a robust increase in cellularity in the mesente
Autor:
Bernard Malissen, Joy Nakawesi, Julia Hütter, Sébastien This, Harry B. Greenberg, L. J. Gooday, A. Garcias López, V. Barateau, Katharina Lahl, K. Getachew Muleta, K. Fog Thomsen, Olivier Thaunat, M. Boucard-Jourdin, T. Defrance, Didier Poncet, Isabel Ulmert, H. Paidassi
Publikováno v:
Mucosal Immunology
Mucosal Immunology, Nature Pub. Group, 2020, ⟨10.1038/s41385-020-0276-8⟩
Mucosal Immunology, 2021, ⟨10.1038/s41385-020-0276-8⟩
Mucosal Immunology, 2020, ⟨10.1038/s41385-020-0276-8⟩
Mucosal Immunology, Nature Pub. Group, 2020, ⟨10.1038/s41385-020-0276-8⟩
Mucosal Immunology, 2021, ⟨10.1038/s41385-020-0276-8⟩
Mucosal Immunology, 2020, ⟨10.1038/s41385-020-0276-8⟩
International audience; Secretory intestinal IgA can protect from re-infection with rotavirus (RV), but very little is known about the mechanisms that induce IgA production during intestinal virus infections. Classical dendritic cells (cDCs) in the i