CCL2-mediated endothelial injury drives cardiac dysfunction in long COVID.

Autor: Thomas D; Stanford Cardiovascular Institute, Stanford University School of Medicine, Stanford, CA, USA.; Division of Cardiology, Department of Medicine, Stanford University School of Medicine, Stanford, CA, USA., Noishiki C; Stanford Cardiovascular Institute, Stanford University School of Medicine, Stanford, CA, USA.; Division of Vascular Surgery, Department of Surgery, Stanford University School of Medicine, Stanford, CA, USA., Gaddam S; Department of Dermatology, Stanford University School of Medicine, Stanford, CA, USA., Wu D; Stanford Cardiovascular Institute, Stanford University School of Medicine, Stanford, CA, USA.; Division of Vascular Surgery, Department of Surgery, Stanford University School of Medicine, Stanford, CA, USA., Manhas A; Stanford Cardiovascular Institute, Stanford University School of Medicine, Stanford, CA, USA.; Division of Cardiology, Department of Medicine, Stanford University School of Medicine, Stanford, CA, USA., Liu Y; Stanford Cardiovascular Institute, Stanford University School of Medicine, Stanford, CA, USA.; Division of Cardiology, Department of Medicine, Stanford University School of Medicine, Stanford, CA, USA., Tripathi D; Stanford Cardiovascular Institute, Stanford University School of Medicine, Stanford, CA, USA.; Division of Vascular Surgery, Department of Surgery, Stanford University School of Medicine, Stanford, CA, USA.; Baszucki Family Vascular Surgery Biobank, Stanford University School of Medicine, Stanford, CA, USA., Kathale N; Division of Infectious Diseases, Department of Medicine, Stanford University School of Medicine, Stanford, CA, USA., Adkar SS; Division of Vascular Surgery, Department of Surgery, Stanford University School of Medicine, Stanford, CA, USA.; Baszucki Family Vascular Surgery Biobank, Stanford University School of Medicine, Stanford, CA, USA., Garhyan J; In Vitro Biosafety Level 3 (BSL3) Service Center, Stanford University School of Medicine, Stanford, CA, USA., Liu C; Departments of Physiology and Medicine, Medical College of Wisconsin, Milwaukee, WI, USA., Xu B; Division of Vascular Surgery, Department of Surgery, Stanford University School of Medicine, Stanford, CA, USA., Ross EG; Division of Vascular and Endovascular Surgery, Department of Surgery, University of California, San Diego, San Diego, CA, USA., Dalman RL; Stanford Cardiovascular Institute, Stanford University School of Medicine, Stanford, CA, USA.; Division of Vascular Surgery, Department of Surgery, Stanford University School of Medicine, Stanford, CA, USA., Wang KC; Department of Dermatology, Stanford University School of Medicine, Stanford, CA, USA., Oro AE; Department of Dermatology, Stanford University School of Medicine, Stanford, CA, USA., Sallam K; Stanford Cardiovascular Institute, Stanford University School of Medicine, Stanford, CA, USA.; Division of Cardiology, Department of Medicine, Stanford University School of Medicine, Stanford, CA, USA., Lee JT; Division of Vascular Surgery, Department of Surgery, Stanford University School of Medicine, Stanford, CA, USA.; Baszucki Family Vascular Surgery Biobank, Stanford University School of Medicine, Stanford, CA, USA., Wu JC; Stanford Cardiovascular Institute, Stanford University School of Medicine, Stanford, CA, USA.; Division of Cardiology, Department of Medicine, Stanford University School of Medicine, Stanford, CA, USA.; Greenstone Biosciences, Palo Alto, CA, USA., Sayed N; Stanford Cardiovascular Institute, Stanford University School of Medicine, Stanford, CA, USA. sayedns@stanford.edu.; Division of Cardiology, Department of Medicine, Stanford University School of Medicine, Stanford, CA, USA. sayedns@stanford.edu.; Division of Vascular Surgery, Department of Surgery, Stanford University School of Medicine, Stanford, CA, USA. sayedns@stanford.edu.; Baszucki Family Vascular Surgery Biobank, Stanford University School of Medicine, Stanford, CA, USA. sayedns@stanford.edu.

Publikováno v: Nature cardiovascular research [Nat Cardiovasc Res] 2024 Oct; Vol. 3 (10), pp. 1249-1265. Date of Electronic Publication: 2024 Oct 14.

Early non-neutralizing, afucosylated antibody responses are associated with COVID-19 severity.

Autor: Chakraborty S; Department of Medicine, Division of Infectious Diseases, Stanford University, Stanford, CA 94304, USA., Gonzalez JC; Department of Medicine, Division of Infectious Diseases, Stanford University, Stanford, CA 94304, USA.; Program in Immunology, Stanford University School of Medicine, Stanford, CA 94305, USA., Sievers BL; J. Craig Venter Institute, La Jolla, CA 92037, USA., Mallajosyula V; Institute for Immunity, Transplantation and Infection, Stanford University School of Medicine, Stanford, CA 94305, USA., Chakraborty S; Department of Computer and Software Engineering, San José State University, San Jose, CA 95192, USA., Dubey M; Department of Microbiology and Immunology, Stanford University School of Medicine, Stanford, CA 94305, USA., Ashraf U; Department of Medicine, Division of Infectious Diseases, Stanford University, Stanford, CA 94304, USA., Cheng BY; Department of Medicine, Division of Infectious Diseases, Stanford University, Stanford, CA 94304, USA., Kathale N; Department of Medicine, Division of Infectious Diseases, Stanford University, Stanford, CA 94304, USA., Tran KQT; Department of Medicine, Division of Infectious Diseases, Stanford University, Stanford, CA 94304, USA., Scallan C; Department of Medicine, Division of Infectious Diseases, Stanford University, Stanford, CA 94304, USA., Sinnott A; J. Craig Venter Institute, La Jolla, CA 92037, USA., Cassidy A; Division of Maternal-Fetal Medicine, Department of Obstetrics, Gynecology and Reproductive Sciences, University of California San Francisco, San Francisco, CA 94143, USA., Chen ST; Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029-5674, USA.; Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029-5674, USA.; Department of Oncological Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029-5674, USA., Gelbart T; J. Craig Venter Institute, La Jolla, CA 92037, USA., Gao F; Institute for Immunity, Transplantation and Infection, Stanford University School of Medicine, Stanford, CA 94305, USA., Golan Y; Department of Bioengineering and Therapeutic Sciences and Institute for Human Genetics, University of California San Francisco, San Francisco, CA 94143, USA., Ji X; Institute for Immunity, Transplantation and Infection, Stanford University School of Medicine, Stanford, CA 94305, USA., Kim-Schulze S; Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029-5674, USA., Prahl M; Division of Pediatric Infectious Diseases, Department of Pediatrics, University of California, San Francisco, CA 94143, USA., Gaw SL; Division of Maternal-Fetal Medicine, Department of Obstetrics, Gynecology and Reproductive Sciences, University of California San Francisco, San Francisco, CA 94143, USA., Gnjatic S; Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029-5674, USA.; Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029-5674, USA.; Department of Oncological Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029-5674, USA.; Human Immune Monitoring Center, Precision Immunology Institute, Department of Oncological Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029-5674, USA., Marron TU; Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029-5674, USA.; Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029-5674, USA., Merad M; Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029-5674, USA.; Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029-5674, USA.; Department of Oncological Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029-5674, USA.; Human Immune Monitoring Center, Precision Immunology Institute, Department of Oncological Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029-5674, USA., Arunachalam PS; Institute for Immunity, Transplantation and Infection, Stanford University School of Medicine, Stanford, CA 94305, USA., Boyd SD; Departments of Pathology and of Microbiology and Immunology, Stanford University School of Medicine, Stanford, CA 94305, USA., Davis MM; Institute for Immunity, Transplantation and Infection, Stanford University School of Medicine, Stanford, CA 94305, USA.; Department of Microbiology and Immunology, Stanford University School of Medicine, Stanford, CA 94305, USA.; Howard Hughes Medical Institute, Stanford University School of Medicine, Stanford, CA 94305, USA., Holubar M; Department of Medicine, Division of Infectious Diseases, Stanford University, Stanford, CA 94304, USA., Khosla C; Departments of Chemistry and Chemical Engineering, Stanford University, Stanford, CA 94305, USA., Maecker HT; Institute for Immunity, Transplantation and Infection, Stanford University School of Medicine, Stanford, CA 94305, USA., Maldonado Y; Department of Pediatrics, Stanford University School of Medicine, Stanford, CA 94305, USA., Mellins ED; Department of Pediatrics, Stanford University School of Medicine, Stanford, CA 94305, USA., Nadeau KC; Sean N. Parker Center for Allergy and Asthma Research, Stanford University, Stanford, CA 94304, USA., Pulendran B; Institute for Immunity, Transplantation and Infection, Stanford University School of Medicine, Stanford, CA 94305, USA., Singh U; Department of Medicine, Division of Infectious Diseases, Stanford University, Stanford, CA 94304, USA.; Department of Microbiology and Immunology, Stanford University School of Medicine, Stanford, CA 94305, USA., Subramanian A; Department of Medicine, Division of Infectious Diseases, Stanford University, Stanford, CA 94304, USA., Utz PJ; Department of Medicine, Division of Immunology and Rheumatology, Stanford University School of Medicine, Stanford, CA 94304, USA., Sherwood R; Proteomics and Metabolomics Facility, Institute of Biotechnology, Cornell University, Ithaca, NY 14853, USA., Zhang S; Proteomics and Metabolomics Facility, Institute of Biotechnology, Cornell University, Ithaca, NY 14853, USA., Jagannathan P; Department of Medicine, Division of Infectious Diseases, Stanford University, Stanford, CA 94304, USA.; Department of Microbiology and Immunology, Stanford University School of Medicine, Stanford, CA 94305, USA., Tan GS; J. Craig Venter Institute, La Jolla, CA 92037, USA.; Division of Infectious Diseases, Department of Medicine, University of California San Diego, La Jolla, CA 92093, USA., Wang TT; Department of Medicine, Division of Infectious Diseases, Stanford University, Stanford, CA 94304, USA.; Department of Microbiology and Immunology, Stanford University School of Medicine, Stanford, CA 94305, USA.; Chan Zuckerberg Biohub, San Francisco, CA 94158, USA.

Publikováno v: Science translational medicine [Sci Transl Med] 2022 Mar 09; Vol. 14 (635), pp. eabm7853. Date of Electronic Publication: 2022 Mar 09.

Inflammasome-Driven Fatal Acute-on-Chronic Liver Failure Triggered by Mild COVID-19.

Autor: Chen, Vivian Chih-Wei¹ (AUTHOR) linfa.wang@duke-nus.edu.sg, Joseph, Craig Ryan² (AUTHOR), Chan, Wharton O. Y.¹ (AUTHOR), Sia, Wan Rong¹ (AUTHOR), Su, Qi¹ (AUTHOR), Sam, Xin Xiu³ (AUTHOR), Tamilarasan, Hemavathi² (AUTHOR), Mah, Yun Yan¹ (AUTHOR), Ng, Wei Lun¹ (AUTHOR), Yeong, Joe^2,4 (AUTHOR), Wang, Lin-Fa^1,5 (AUTHOR), Krishnamoorthy, Thinesh L.⁶ (AUTHOR), Leow, Wei-Qiang³ (AUTHOR), Ahn, Matae^1,7,8 (AUTHOR) ahn.matae11@u.duke.nus.edu, Chow, Wan Cheng^6,7 (AUTHOR) ahn.matae11@u.duke.nus.edu

Publikováno v: Viruses (1999-4915). Oct2024, Vol. 16 Issue 10, p1646. 12p.

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Interplay between Comorbidities and Long COVID: Challenges and Multidisciplinary Approaches.

Autor: Ashmawy, Rasha^1,2 (AUTHOR) hiph.eabdellatif@alexu.edu.eg, Hammouda, Esraa Abdellatif^2,3 (AUTHOR), El-Maradny, Yousra A.^4,5 (AUTHOR) hiph.ymaradny@alexu.edu.eg, Aboelsaad, Iman¹ (AUTHOR) mri.iman.m.informatics18@alexu.edu.eg, Hussein, Mai¹ (AUTHOR) mai.mk.hussein@gmail.com, Uversky, Vladimir N.⁶ (AUTHOR) vuversky@usf.edu, Redwan, Elrashdy M.^7,8 (AUTHOR) vuversky@usf.edu

Publikováno v: Biomolecules (2218-273X). Jul2024, Vol. 14 Issue 7, p835. 24p.