Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Katey Witham"'
Autor:
Alexandra C I Depelsenaire, Katey Witham, Margaret Veitch, James W Wells, Christopher D Anderson, Jason D Lickliter, Steve Rockman, Jesse Bodle, Peter Treasure, Julian Hickling, Germain J P Fernando, Angus H Forster
Publikováno v:
PLoS ONE, Vol 16, Iss 7, p e0255282 (2021)
Microarray patches (MAPs) have the potential to be a safer, more acceptable, easier to use and more cost-effective method for administration of vaccines when compared to the needle and syringe. Since MAPs deliver vaccine to the dermis and epidermis,
Externí odkaz:
https://doaj.org/article/61371d0df36f45c29c01e75d282c49e0
Autor:
Angus H Forster, Katey Witham, Alexandra C I Depelsenaire, Margaret Veitch, James W Wells, Adam Wheatley, Melinda Pryor, Jason D Lickliter, Barbara Francis, Steve Rockman, Jesse Bodle, Peter Treasure, Julian Hickling, Germain J P Fernando
Publikováno v:
PLoS Medicine, Vol 17, Iss 3, p e1003024 (2020)
BACKGROUND:The Vaxxas high-density microarray patch (HD-MAP) consists of a high density of microprojections coated with vaccine for delivery into the skin. Microarray patches (MAPs) offer the possibility of improved vaccine thermostability as well as
Externí odkaz:
https://doaj.org/article/ccf4986e714c4d7486a7312cd803f8b1
Autor:
Steve Rockman, Julian Hickling, Jason D. Lickliter, Christopher D. Anderson, Peter Treasure, Jesse Bodle, Angus Forster, Alexandra C. I. Depelsenaire, Germain J. P. Fernando, Margaret Veitch, Katey Witham, James W. Wells
Publikováno v:
PLoS ONE, Vol 16, Iss 7, p e0255282 (2021)
PLoS ONE
PLoS ONE
Microarray patches (MAPs) have the potential to be a safer, more acceptable, easier to use and more cost-effective method for administration of vaccines when compared to the needle and syringe. Since MAPs deliver vaccine to the dermis and epidermis,
Autor:
Katey Witham, Sangeeta B. Joshi, Christopher Bird, John M. Hickey, Paul Fahey, Angus Forster, David B. Volkin, Ying Wan
Publikováno v:
Journal of Pharmaceutical Sciences
The worldwide switch to inactivated polio vaccines (IPVs) is a key component of the overall strategy to achieve and maintain global polio eradication. To this end, new IPV vaccine delivery systems may enhance patient convenience and compliance. In th
Publikováno v:
Biochemical Pharmacology. 125:93-100
The Phase II drug metabolizing enzyme arylamine N-acetyltransferase 1 (NAT1) has been implicated in the growth and survival of cancer cells, although the mechanisms that underlies these effects are unknown. Here, a focused metabolomics approach was u
Autor:
Adam K. Wheatley, Julian Hickling, Barbara Francis, Melinda Pryor, Katey Witham, James W. Wells, Angus Forster, Germain J. P. Fernando, Steve Rockman, Alexandra C. I. Depelsenaire, Margaret Veitch, Jason D. Lickliter, Jesse Bodle, Peter Treasure
Publikováno v:
PLoS Medicine
PLoS Medicine, Vol 17, Iss 3, p e1003024 (2020)
PLoS Medicine, Vol 17, Iss 3, p e1003024 (2020)
Background The Vaxxas high-density microarray patch (HD-MAP) consists of a high density of microprojections coated with vaccine for delivery into the skin. Microarray patches (MAPs) offer the possibility of improved vaccine thermostability as well as
Autor:
Katey Witham, Vinod Kumar, Richard H. Finnell, Kerina J. Denny, Trent M. Woodruff, Angela Jeanes, Christina F. Kelly, Stephen M. Taylor, Robert M. Cabrera
Publikováno v:
Birth Defects Research Part A: Clinical and Molecular Teratology. 106:201-207
Background Periconceptional supplementation with folic acid results in a significant reduction in the incidence of neural tube defects (NTDs). Nonetheless, NTDs remain a leading cause of perinatal morbidity and mortality worldwide, and the mechanism(
Autor:
S. Rachel Skinner, Jesse Bodle, Julian Hickling, Cristyn Davies, Cesar M. Jayashi Flores, Paul M. Griffin, Christopher D. Anderson, Steve Rockman, Melinda Pryor, Ian H. Frazer, Katey Witham, Germain J. P. Fernando, Angus Forster
Background: Injection using needle and syringe (Namp;S) is the most widely used method for vaccination, but requires trained healthcare workers. Fear of needles, risk of needle-stick injury, and the need to reconstitute lyophilised vaccines, are also
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fc2804d2f4868739759d532047590eb
http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-149717
http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-149717
Autor:
Justin R. Scott, Andrew G. Pearson, Katey Witham, Carwyn Davies, Elizabeth M. J. Gillam, Sandra E. Graham, James J. DeVoss
Publikováno v:
Drug Metabolism and Disposition. 32:431-436
CYP2C9 is distinguished by a preference for substrates bearing a negative charge at physiological pH. Previous studies have suggested that CYP2C9 residues R97 and K72 may play roles in determining preference for anionic substrates by interaction at t
Autor:
Debbie Brenneman, Kim S. Sugamori, Rodney F. Minchin, Denis M. Grant, Katey Witham, Neville J. Butcher
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e77923 (2013)
PLoS ONE
PLoS ONE
Folate catabolism involves cleavage of the C(9)-N(10) bond to form p-aminobenzoylgluamate (PABG) and pterin. PABG is then acetylated by human arylamine N-acetyltransferase 1 (NAT1) before excretion in the urine. Mice null for the murine NAT1 homolog