Design, Synthesis, Evaluation and Structure of Allenic 1α,25‐Dihydroxyvitamin D3 Analogs with Locked Mobility at C‐17

Autor: Miguel A. Maestro, Antonio Mouriño, Gilles Laverny, Régis Lutzing, Ramón Fraga, Enrique Rodriguez-Borges, Julian Loureiro, Natacha Rochel, Kateryna Len

Publikováno v: Chemistry (Weinheim an Der Bergstrasse, Germany)
Chemistry-A European Journal
Chemistry-A European Journal, Wiley-VCH Verlag, 2021, 27 (53), pp.13384-13389. ⟨10.1002/chem.202101578⟩
Minerva. Repositorio Institucional de la Universidad de Santiago de Compostela
instname
Chemistry-A European Journal, 2021, 27 (53), pp.13384-13389. ⟨10.1002/chem.202101578⟩

Vitamin D receptor ligands have potential for the treatment of hyperproliferative diseases and disorders related to the immune system. However, hypercalcemic effects limit their therapeutical uses and call for the development of tissue‐selective ne

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3508bafd65b0a8d8bf82201845d3e680
http://europepmc.org/articles/PMC8519077