Zobrazeno 1 - 10
of 67
pro vyhledávání: '"Katerina Zavitsanou"'
Autor:
Tasnim Rahman, Katerina Zavitsanou, Tertia Purves-Tyson, Lauren R. Harms, Crystal Meehan, Ulrich Schall, Juanita Todd, Deborah M. Hodgson, Patricia T. Michie, Cyndi Shannon Weickert
Publikováno v:
Frontiers in Psychiatry, Vol 8 (2017)
BackgroundGlutamatergic receptor [N-methyl-d-aspartate receptor (NMDAR)] alterations within cortex, hippocampus, and striatum are linked to schizophrenia pathology. Maternal immune activation (MIA) is an environmental risk factor for the development
Externí odkaz:
https://doaj.org/article/6a7f95367374456194f5d208f61eec54
Autor:
Lauren Harms, W Ross Fulham, Juanita Todd, Timothy W Budd, Michael Hunter, Crystal Meehan, Markku Penttonen, Ulrich Schall, Katerina Zavitsanou, Deborah M Hodgson, Patricia T Michie
Publikováno v:
PLoS ONE, Vol 9, Iss 10, p e110892 (2014)
Mismatch negativity (MMN) is a scalp-recorded electrical potential that occurs in humans in response to an auditory stimulus that defies previously established patterns of regularity. MMN amplitude is reduced in people with schizophrenia. In this stu
Externí odkaz:
https://doaj.org/article/e36794b88c454f4a90285219e973cac8
Publikováno v:
PLoS ONE, Vol 8, Iss 1, p e52724 (2013)
GABA(A) receptors (GABA(A)R) are composed of several subunits that determine sensitivity to drugs, synaptic localisation and function. Recent studies suggest that agonists targeting selective GABA(A)R subunits may have therapeutic value against the c
Externí odkaz:
https://doaj.org/article/470b8b663dc54d8e971097642aef2ac1
Publikováno v:
Brain, Behavior, and Immunity. 56:187-196
Maternal immune activation (MIA) and adolescent cannabinoid exposure (ACE) have both been identified as major environmental risk factors for schizophrenia. We examined the effects of these two risk factors alone, and in combination, on gene expressio
Autor:
Jason M. Bruggemann, Dennis Liu, Cynthia Shannon Weickert, Thomas W. Weickert, Chai K. Lim, Cherrie Galletly, Gilles J. Guillemin, Ryan P. Balzan, Danny Boerrigter, Jochen Kindler, Rhoshel K. Lenroot, Maryanne O'Donnell, Katerina Zavitsanou
Background: The kynurenine pathway (KP) of tryptophan (TRP) catabolism is considered to link the immune and neurotransmitter systems. The KP metabolite kynurenic acid (KYNA) shows increases in the brain of patients with schizophrenia. Here, we tested
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aeb155453f53b776b2d92cdcaf569381
https://europepmc.org/articles/PMC5475646/
https://europepmc.org/articles/PMC5475646/
Autor:
Tasnim, Rahman, Katerina, Zavitsanou, Tertia, Purves-Tyson, Lauren R, Harms, Crystal, Meehan, Ulrich, Schall, Juanita, Todd, Deborah M, Hodgson, Patricia T, Michie, Cyndi Shannon, Weickert
Publikováno v:
Frontiers in Psychiatry
Background Glutamatergic receptor [N-methyl-d-aspartate receptor (NMDAR)] alterations within cortex, hippocampus, and striatum are linked to schizophrenia pathology. Maternal immune activation (MIA) is an environmental risk factor for the development
Autor:
Adam K. Walker, Luba Sominsky, Deborah M. Hodgson, Cynthia Shannon Weickert, Katerina Zavitsanou, Victoria S. Dalton
Publikováno v:
Synapse. 67:290-299
Brain inflammation in early life has been proposed to play important roles in the development of anxiety and psychosis-related behaviors in adulthood, behaviors that rely on the integrity of dopamine and/or serotonin systems. Moreover recent behavior
Autor:
Lauren Harms, Rafael Barreto, Jade D. Frost, Katerina Zavitsanou, Juanita Todd, Patricia T. Michie, Cynthia Shannon Weickert, Ulrich Schall, Crystal L. Meehan, Deborah M. Hodgson
Publikováno v:
Brain, behavior, and immunity. 63
Maternal exposure to infectious agents during gestation has been identified as a significant risk factor for schizophrenia. Using a mouse model, past work has demonstrated that the gestational timing of the immune-activating event can impact the beha
Publikováno v:
European Neuropsychopharmacology. 22:683-694
The atypical antipsychotics bind multiple receptor targets, including dopamine D₂ receptors (DRD2), 5-HT₂ receptors (HTR2A), α-2 adrenergic receptors (ADRA2A), and muscarinic receptors (CHRM1/4). Deficits in antipsychotic targets, their associat
Publikováno v:
Pharmacology. 89:64-73
Background/Aims: Functional linkages between the cannabinoid CB1 and the dopaminergic systems have been reported although the observations and the mechanisms hypothesizing their interactions at the G protein-coupled receptor (GPCR) functionality leve