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of 6
pro vyhledávání: '"Katerina Westlake"'
Autor:
Minh Duc Trinh, Andrea Plihalova, Jan Gojda, Katerina Westlake, Jan Spicka, Zuzana Lattova, Martin Pretl, Jan Polak
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Abstract Obstructive sleep apnoea (OSA) is associated with type 2 diabetes mellitus (T2DM). However, mechanisms mediating association between these two conditions remain unclear. This study investigated, whether the OSA-associated changes in adipose
Externí odkaz:
https://doaj.org/article/b654acfdddb24e6d9d3683bc0f73b021
Publikováno v:
Frontiers in Endocrinology, Vol 9 (2018)
Obstructive sleep apnea (OSA) is a common disorder in Type 2 diabetes (T2D) patients further increasing their already high cardiovascular risk. As T2D patients typically not report OSA symptoms, systematic screening for OSA in this population is warr
Externí odkaz:
https://doaj.org/article/7d4aa2f3e2244de3b42ca15167382ef0
Autor:
Zuzana Lattova, Lucie Slovakova, Andrea Plihalova, Jan Gojda, Moustafa Elkalaf, Katerina Westlake, Jan Polak
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 6; Pages: 5308
The molecular mechanisms linking obstructive sleep apnea (OSA) with type 2 diabetes mellitus (T2DM) remain unclear. This study investigated the effect of OSA on skeletal muscle lipid oxidation in nondiabetic controls and in type 2 diabetes (T2DM) pat
Publikováno v:
Sleep Medicine. 26:71-76
Background Obstructive sleep apnea (OSA) is highly prevalent in patients with Type 2 diabetes mellitus representing an additional risk factor for already increased cardiovascular mortality. As cardiovascular diseases are the main cause of death in th
Adipogenesis, lipogenesis and lipolysis is stimulated by mild but not severe hypoxia in 3T3-L1 cells
Autor:
Michal Koc, Jan Pala, Jan Polak, Martin Weiszenstein, Jan Trnka, Sumeet Gulati, Katerina Westlake, Moustafa Elkalaf, Andrea Plihalova, Antonin Prochazka, Martina Musutova
Publikováno v:
Biochemical and Biophysical Research Communications. 478:727-732
In-vitro investigation of the effects of hypoxia is limited by physical laws of gas diffusion and cellular O2 consumption, making prolonged exposures to stable O2 concentrations impossible. Using a gas-permeable cultureware, chronic effects of mild a
Autor:
Jan Polak, Katerina Westlake
Publikováno v:
Frontiers in Endocrinology
The shorter life expectancy of patients with type 2 diabetes caused by cardiovascular and cerebrovascular diseases compels clinicians to make a systematic effort to address traditional cardiovascular risk factors, such as dyslipidemia, hypertension,