Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Katerina Menelaou"'
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Abnormal uptake or metabolism of folate increases risk of human pregnancy complications, though the mechanism is unclear. Here, we explore how defective folate metabolism influences early development by analysing mice with the hypomorphic Mtrrgt muta
Externí odkaz:
https://doaj.org/article/553ff89818d34589bf178f5560e08b38
Autor:
Shiya Cheng, Gerrit Altmeppen, Chun So, Luisa M. Welp, Sarah Penir, Torben Ruhwedel, Katerina Menelaou, Katarina Harasimov, Alexandra Stützer, Martyn Blayney, Kay Elder, Wiebke Möbius, Henning Urlaub, Melina Schuh
Publikováno v:
Science (New York, N.Y.). 378(6617)
Full-grown oocytes are transcriptionally silent and must stably maintain the messenger RNAs (mRNAs) needed for oocyte meiotic maturation and early embryonic development. However, where and how mammalian oocytes store maternal mRNAs is unclear. Here,
Autor:
Chun So, Katerina Menelaou, Julia Uraji, Katarina Harasimov, Anna M. Steyer, K. Bianka Seres, Jonas Bucevičius, Gražvydas Lukinavičius, Wiebke Möbius, Claus Sibold, Andreas Tandler-Schneider, Heike Eckel, Rüdiger Moltrecht, Martyn Blayney, Kay Elder, Melina Schuh
Publikováno v:
J Assist Reprod Genet
Human oocytes are prone to assembling meiotic spindles with unstable poles, which can favor aneuploidy in human eggs. The underlying causes of spindle instability are unknown. We found that NUMA (nuclear mitotic apparatus protein)–mediated clusteri
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Frontiers in Cell and Developmental Biology
Frontiers in Cell and Developmental Biology
Abnormal uptake or metabolism of folate increases risk of human pregnancy complications, though the mechanism is unclear. Here, we explore how defective folate metabolism influences early development by analysing mice with the hypomorphic Mtrr gt mut
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f99e0d07612bc9b72e29aa0954818f0
Autor:
Colleen Geary Joo, Georgina E T Blake, Malwina Prater, Erica D. Watson, Russell S. Hamilton, Katerina Menelaou, Simon James Tunster, James C. Cross
Publikováno v:
Reproduction (Cambridge, England)
Assisted reproduction technologies (ARTs) are becoming increasingly common. Therefore, how these procedures influence gene regulation and foeto-placental development are important to explore. Here, we assess the effects of blastocyst transfer on mous
Autor:
Nisha, Padmanabhan, Katerina, Menelaou, Jiali, Gao, Alexander, Anderson, Georgina E T, Blake, Tanya, Li, B Nuala, Daw, Erica D, Watson
Publikováno v:
The Journal of Physiology
Key points Folate (folic acid) deficiency and mutations in folate‐related genes in humans result in megaloblastic anaemia.Folate metabolism, which requires the enzyme methionine synthase reductase (MTRR), is necessary for DNA synthesis and the tran
Autor:
Georgina E T Blake, Joanna Rakoczy, Nisha Padmanabhan, Erica D. Watson, Monika Kondratowicz, Katerina Menelaou
Publikováno v:
Environmental Epigenetics
The exposure to adverse environmental conditions (e.g. poor nutrition) may lead to increased disease risk in an individual and their descendants. In some cases, the results may be sexually dimorphic. A range of phenotypes has been associated with def
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60884b2a8b5f1208fd2d69bdb08acad6
https://www.repository.cam.ac.uk/handle/1810/267334
https://www.repository.cam.ac.uk/handle/1810/267334