Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Katerina Goudevenou"'
Publikováno v:
Biomedicines, Vol 11, Iss 12, p 3297 (2023)
Overexpression of the inducible heme oxygenase (HO-1) isoform in visceral renal glomerular epithelial cells (podocytes) using in vivo transgenesis methods was shown to increase glomerular expression of the complement regulatory protein decay-accelera
Externí odkaz:
https://doaj.org/article/2027aabf76a84519955ccacdd87f2337
Autor:
Ivo S. Muskens, Shaobo Li, Thomas Jackson, Natalina Elliot, Helen M. Hansen, Swe Swe Myint, Priyatama Pandey, Jeremy M. Schraw, Ritu Roy, Joaquin Anguiano, Katerina Goudevenou, Kimberly D. Siegmund, Philip J. Lupo, Marella F. T. R. de Bruijn, Kyle M. Walsh, Paresh Vyas, Xiaomei Ma, Anindita Roy, Irene Roberts, Joseph L. Wiemels, Adam J. de Smith
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Down syndrome has a high co-morbidity with immune and hematopoietic disorders. Here, the authors perform an epigenome-wide association study in newborns with and without Down syndrome to find differential methylation across the genome, including in h
Externí odkaz:
https://doaj.org/article/638c652373704f3aa4579682f8dc481e
Publikováno v:
PLoS ONE, Vol 6, Iss 10, p e26548 (2011)
During gastrulation, convergent extension (CE) cell movements are regulated through the non-canonical Wnt signaling pathway. Wnt signaling results in downstream activation of Rho GTPases that in turn regulate actin cytoskeleton rearrangements essenti
Externí odkaz:
https://doaj.org/article/3b754d35865045ad9afd3697a6f29846
Autor:
Dimitra Kerdidani, Emmanouil Aerakis, Kleio-Maria Verrou, Ilias Angelidis, Katerina Douka, Maria-Anna Maniou, Petros Stamoulis, Katerina Goudevenou, Alejandro Prados, Christos Tzaferis, Vasileios Ntafis, Ioannis Vamvakaris, Evangelos Kaniaris, Konstantinos Vachlas, Evangelos Sepsas, Anastasios Koutsopoulos, Konstantinos Potaris, Maria Tsoumakidou
Publikováno v:
Journal of Experimental Medicine
A key unknown of the functional space in tumor immunity is whether CD4 T cells depend on intratumoral MHCII cancer antigen recognition. MHCII-expressing, antigen-presenting cancer-associated fibroblasts (apCAFs) have been found in breast and pancreat
Autor:
Swe Swe Myint, Shaobo Li, Ivo S. Muskens, Kimberly D. Siegmund, Philip J. Lupo, Marella F. T. R. de Bruijn, Helen M. Hansen, Natalina Elliot, Kyle M. Walsh, Anindita Roy, Priyatama Pandey, Irene Roberts, Paresh Vyas, Katerina Goudevenou, Joaquin Anguiano, Thomas Jackson, Joseph L. Wiemels, Adam J. de Smith, Ritu Roy, Xiaomei Ma, Jeremy M. Schraw
Publikováno v:
Nature communications, vol 12, iss 1
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Down syndrome is associated with genome-wide perturbation of gene expression, which may be mediated by epigenetic changes. We perform an epigenome-wide association study on neonatal bloodspots comparing 196 newborns with Down syndrome and 439 newborn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07b0b06eeffeb867aef5393b48824543
https://doi.org/10.1038/s41467-021-21064-z
https://doi.org/10.1038/s41467-021-21064-z
Autor:
Konstantinos Potaris, Kleio Verrou, Konstantinos Vachlas, Maria Tsoumakidou, Anastasios Koutsopoulos, Alejandro Prados, Petros Stamoulis, Emmanouil Aerakis, Katerina Goudevenou, Ioannis Vamvakaris, Evangelos Kaniaris, Christos Tzaferis, Evangelos Sepsas, Dimitra Kerdidani
In situ antigen presentation is required to sustain active proliferating CD4+ T cells in tumours and to help form memory CD8+ T cells, but the antigen presenting cells (APCs) and pathways involved remain elusive. Cancer associated fibroblasts (CAFs)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a86ef256a64ab9e20803fdb6cd0f2106
https://doi.org/10.1101/2020.03.24.005355
https://doi.org/10.1101/2020.03.24.005355
Autor:
Antonia, Rotolo, Valentina S, Caputo, Monika, Holubova, Nicoleta, Baxan, Olivier, Dubois, Mohammed Suhail, Chaudhry, Xiaolin, Xiao, Katerina, Goudevenou, David S, Pitcher, Kyriaki, Petevi, Carolina, Kachramanoglou, Sandra, Iles, Kikkeri, Naresh, John, Maher, Anastasios, Karadimitris
Publikováno v:
Cancer Cell
Summary Chimeric antigen receptor anti-CD19 (CAR19)-T cell immunotherapy-induced clinical remissions in CD19+ B cell lymphomas are often short lived. We tested whether CAR19-engineering of the CD1d-restricted invariant natural killer T (iNKT) cells w
Autor:
David S. Pitcher, Amin Rahemtulla, Irene Roberts, Maurits F. Kleijnen, Ziming Wang, Kate de Mattos-Shipley, Katerina Goudevenou, Ambrosius P. Snijders, Georg Bohn, Konstantinos N. Tzortzis, Anastasios Karadimitris, Helen R. Flynn
Publikováno v:
Europe PubMed Central
We report that subunits of human nuclear proteasomes carry a previously unrecognised, constitutive posttranslational modification. Subunits with this modification are not visualised by SDS-PAGE, which is used in almost all denaturing protein gel elec
Autor:
Raymond A. Dwek, Lynett Danks, Simon Parry, Aristeidis Chaidos, Emmanouil Spanoudakis, Adel Ersek, Anastasios Karadimitris, Gabriele Twigg, Evdoxia Hatjiharissi, Terry D. Butters, Aristotelis Antonopoulos, Irene Roberts, Amin Rahemtulla, Ming Hu, A Freidin, Stuart M. Haslam, Youridies Vattakuzhi, Anne Dell, Lynn M. Williams, Ke Xu, Nicole J. Horwood, Katerina Goudevenou, Dominic S. Alonzi, Ana Isabel Espirito Santo, Maria Papaioannou
Glycosphingolipids (GSLs) are essential constituents of cell membranes and lipid rafts and can modulate signal transduction events. The contribution of GSLs in osteoclast (OC) activation and osteolytic bone diseases in malignancies such as the plasma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9655453b82313a6065338c85f400aec
https://doi.org/10.1172/jci59987
https://doi.org/10.1172/jci59987
Autor:
Anastasios Karadimitris, Katerina Goudevenou, Valentina S. Caputo, Xiaolin Xiao, Kanagaraju Ponnusamy, Aristeidis Chaidos
Publikováno v:
Stem cells (Dayton, Ohio). 33(11)
Multiple myeloma (MM) is an incurable tumor of the plasma cells, the terminally differentiated immunoglobulin secreting B lineage cells. The genetic make-up of MM has been extensively characterized but its impact on the biology of the disease is inco