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Autor:
Galina V. Kopylova, Alexander M. Matyushenko, Anastasia V. Pivovarova, Katerina E. Popruga, Sergey Y. Bershitsky, Dmitrii I. Levitsky, Natalya V. Artemova, D. V. Shchepkin
Publikováno v:
Biochemistry. 56(1)
Hypertrophic cardiomyopathy (HCM) is a severe heart disease caused by missense mutations in genes encoding sarcomeric proteins of cardiac muscle. Many of these mutations are identified in the gene encoding the cardiac isoform of tropomyosin (Tpm), an