Zobrazeno 1 - 10
of 261
pro vyhledávání: '"Katerina Akassoglou"'
Autor:
Stephanie R. Miller, Kevin Luxem, Kelli Lauderdale, Pranav Nambiar, Patrick S. Honma, Katie K. Ly, Shreya Bangera, Mary Bullock, Jia Shin, Nick Kaliss, Yuechen Qiu, Catherine Cai, Kevin Shen, K. Dakota Mallen, Zhaoqi Yan, Andrew S. Mendiola, Takashi Saito, Takaomi C. Saido, Alexander R. Pico, Reuben Thomas, Erik D. Roberson, Katerina Akassoglou, Pavol Bauer, Stefan Remy, Jorge J. Palop
Publikováno v:
Cell Reports, Vol 43, Iss 11, Pp 114870- (2024)
Summary: Computer-vision and machine-learning (ML) approaches are being developed to provide scalable, unbiased, and sensitive methods to assess mouse behavior. Here, we used the ML-based variational animal motion embedding (VAME) segmentation platfo
Externí odkaz:
https://doaj.org/article/624d2d95b9884a1bbb7878c8a321d192
Autor:
Terry Dean, Andrew S. Mendiola, Zhaoqi Yan, Rosa Meza-Acevedo, Belinda Cabriga, Katerina Akassoglou, Jae Kyu Ryu
Publikováno v:
Journal of Neuroinflammation, Vol 21, Iss 1, Pp 1-12 (2024)
Abstract Background Traumatic brain injury (TBI) causes significant blood-brain barrier (BBB) breakdown, resulting in the extravasation of blood proteins into the brain. The impact of blood proteins, especially fibrinogen, on inflammation and neurode
Externí odkaz:
https://doaj.org/article/7233fd5f06d7435ea3d6205febe45bb3
Autor:
Thomas Payne, Jennifer Taylor, David Kunkel, Katherine Konieczka, Frankie Ingram, Kaj Blennow, Henrik Zetterberg, Robert A. Pearce, Anke Meyer-Franke, Niccolò Terrando, Katerina Akassoglou, Robert D. Sanders, Richard C. Lennertz
Publikováno v:
BJA Open, Vol 12, Iss , Pp 100349- (2024)
Background: We aimed to assess perioperative changes in fibrinogen in the cerebrospinal fluid (CSF), their association with markers of blood–brain barrier breakdown and neuroinflammation, and their association with postoperative delirium severity.
Externí odkaz:
https://doaj.org/article/46f97a63a6754a3c850420900105059e
Autor:
Lauriane Pous, Sachin S. Deshpande, Suvra Nath, Szilvia Mezey, Subash C. Malik, Sebastian Schildge, Christian Bohrer, Könül Topp, Dietmar Pfeifer, Francisco Fernández-Klett, Soroush Doostkam, Dennis K. Galanakis, Verdon Taylor, Katerina Akassoglou, Christian Schachtrup
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
The molecular mechanisms regulating adult neural stem/progenitor cell differentiation following damage of the central nervous system are unclear. Here, the authors show that fibrinogen is a regulator of the adult neural stem/progenitor cell switch fr
Externí odkaz:
https://doaj.org/article/f3d973f0777646bfaf11ff6400d0b81e
Autor:
Reshmi Tognatta, Mario Merlini, Zhaoqi Yan, Renaud Schuck, Dimitrios Davalos, Katerina Akassoglou
Publikováno v:
STAR Protocols, Vol 2, Iss 3, Pp 100638- (2021)
Summary: Deposition of the blood coagulation factor fibrinogen in the central nervous system is a hallmark of neurological diseases with blood-brain barrier disruption. We describe in vivo two-photon imaging of microglial responses and neuronal spine
Externí odkaz:
https://doaj.org/article/ff808f9c7d194d29b4a1ce391c868ff8
Autor:
Niccolò Terrando, Katerina Akassoglou
Publikováno v:
British Journal of Anaesthesia. 129:147-150
Systemic perturbations such as peripheral surgical trauma induce neurovascular, inflammatory, and cognitive changes. The blood-brain barrier is a key interface between the periphery and the central nervous system, and is critically involved in regula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67ad8f56c2e9030e6aca24e75f3e96d2
https://doi.org/10.1016/j.bja.2022.05.004
https://doi.org/10.1016/j.bja.2022.05.004
Autor:
Bernat Baeza-Raja, Benjamin D. Sachs, Pingping Li, Frank Christian, Eirini Vagena, Dimitrios Davalos, Natacha Le Moan, Jae Kyu Ryu, Shoana L. Sikorski, Justin P. Chan, Miriam Scadeng, Susan S. Taylor, Miles D. Houslay, George S. Baillie, Alan R. Saltiel, Jerrold M. Olefsky, Katerina Akassoglou
Publikováno v:
Cell Reports, Vol 14, Iss 2, Pp 255-268 (2016)
Obesity and metabolic syndrome reflect the dysregulation of molecular pathways that control energy homeostasis. Here, we show that the p75 neurotrophin receptor (p75NTR) controls energy expenditure in obese mice on a high-fat diet (HFD). Despite no c
Externí odkaz:
https://doaj.org/article/6df01ed55e9b4e4795aea5d1c5382970
Autor:
Jeffrey L. Browning, Jag Bhawan, Anna Tseng, Nicholas Crossland, Andreea M Bujor, Katerina Akassoglou, Shervin Assassi, Brian Skaug, Jonathan Ho
Publikováno v:
bioRxiv
Systemic sclerosis (SSc) is an autoimmune disease characterized by progressive multiorgan fibrosis. While the cause of SSc remains unknown, a perturbed vasculature is considered a critical early step in the pathogenesis. Using fibrinogen as a marker
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5b5ee09333e1f5a26a500334af36738
https://doi.org/10.1101/2023.01.16.523256
https://doi.org/10.1101/2023.01.16.523256
Blood‐brain barrier dysfunction is associated with A/T/N biomarkers and cognition in the aging brain
Autor:
Yasmine Tabdili, Krystal Courtney D Belmonte, Nivetha Brathaban, Emma Iorio, Ryan Park, Anna M VandeBunte, Kaitlin B Casaletto, Joel H. Kramer, Katerina Akassoglou, Fanny M Elahi
Publikováno v:
Alzheimer's & Dementia. 18
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::df2a83f4d2b4986da84727fec458a87f
https://doi.org/10.1002/alz.066675
https://doi.org/10.1002/alz.066675