Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Katerina, Papanikolopoulou"'
Publikováno v:
Frontiers in Molecular Biosciences, Vol 11 (2024)
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease with severe socio-economic impact. A hallmark of ALS pathology is the presence of aberrant cytoplasmic inclusions composed of misfolded and aggregated proteins, including both w
Externí odkaz:
https://doaj.org/article/9c14b1b4739f44caa8a363a5ba1810e0
Autor:
Maria-Christina Zerva, Christos Triantafylloudis, Vassilis Paspaliaris, Efthimios M. C. Skoulakis, Katerina Papanikolopoulou
Publikováno v:
Cells, Vol 13, Iss 9, p 746 (2024)
Impaired neuronal plasticity and cognitive decline are cardinal features of Alzheimer’s disease and related Tauopathies. Aberrantly modified Tau protein and neurotransmitter imbalance, predominantly involving acetylcholine, have been linked to thes
Externí odkaz:
https://doaj.org/article/a1d74a3e2ecd4fa09e3dd2ef23397458
Publikováno v:
Genomics, Proteomics & Bioinformatics, Vol 20, Iss 3, Pp 578-586 (2022)
The Network Makeup Artist (NORMA) is a web tool for interactive network annotation visualization and topological analysis, able to handle multiple networks and annotations simultaneously. Precalculated annotations (e.g., Gene Ontology, Pathway enrich
Externí odkaz:
https://doaj.org/article/8634439f175f462ea6224614ab85ecd6
Autor:
Engie Prifti, Eleni N. Tsakiri, Ergina Vourkou, George Stamatakis, Martina Samiotaki, Efthimios M. C. Skoulakis, Katerina Papanikolopoulou
Publikováno v:
Acta Neuropathologica Communications, Vol 10, Iss 1, Pp 1-19 (2022)
Abstract Tau accumulation is clearly linked to pathogenesis in Alzheimer’s disease and other Tauopathies. However, processes leading to Tau fibrillization and reasons for its pathogenicity remain largely elusive. Mical emerged as a novel interactin
Externí odkaz:
https://doaj.org/article/003b9782d55a4e818177a54da6fffa4d
Autor:
Dimitrios Kadas, Katerina Papanikolopoulou, Sofia Xirou, Christos Consoulas, Efthimios M.C. Skoulakis
Publikováno v:
Neurobiology of Disease, Vol 124, Iss , Pp 311-321 (2019)
Accumulation of normal or mutant human Tau isoforms in Central Nervous System (CNS) neurons of vertebrate and invertebrate models underlies pathologies ranging from behavioral deficits to neurodegeneration that broadly recapitulate human Tauopathies.
Externí odkaz:
https://doaj.org/article/10c4a56930d843cf9b2f5cbbf43e2ee1
Autor:
Engie Prifti, Eleni N. Tsakiri, Ergina Vourkou, George Stamatakis, Martina Samiotaki, Efthimios M. C. Skoulakis, Katerina Papanikolopoulou
Publikováno v:
Acta Neuropathologica Communications, Vol 10, Iss 1, Pp 1-1 (2022)
Externí odkaz:
https://doaj.org/article/d82b8f990a2143388eb21778a92ac0e7
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 13 (2020)
Hyperphosphorylated Tau protein is the main component of the neurofibrillary tangles, characterizing degenerating neurons in Alzheimer’s disease and other Tauopathies. Expression of human Tau protein in Drosophila CNS results in increased toxicity,
Externí odkaz:
https://doaj.org/article/dd5057495b414402b99724667b0087bc
Autor:
Chrysoula Kokotidou, Fani Tsitouroudi, Georgios Nistikakis, Marita Vasila, Katerina Papanikolopoulou, Androniki Kretsovali, Anna Mitraki
Publikováno v:
Biomolecules, Vol 12, Iss 2, p 308 (2022)
Protein-based carriers are promising vehicles for the intracellular delivery of therapeutics. In this study, we designed and studied adenovirus protein fiber constructs with potential applications as carriers for the delivery of protein and nanoparti
Externí odkaz:
https://doaj.org/article/8c8d2ebd389a4439b79d89fb8d11f60b
Autor:
Ergina Vourkou, Vassilis Paspaliaris, Anna Bourouliti, Maria-Christina Zerva, Engie Prifti, Katerina Papanikolopoulou, Efthimios M. C. Skoulakis
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 21; Pages: 12985
Accumulation of highly post-translationally modified tau proteins is a hallmark of neurodegenerative disorders known as tauopathies, the most common of which is Alzheimer’s disease. Although six tau isoforms are found in the human brain, the majori
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e8e17730002ac8d6583d908bceb18a4
Autor:
Engie Prifti, Katerina Papanikolopoulou, Ergina Vourkou, George Stamatakis, Martina Samiotaki, Eleni N. Tsakiri
Publikováno v:
J Neurosci
Although Tau accumulation is clearly linked to pathogenesis in Alzheimer's disease and other Tauopathies, the mechanism that initiates the aggregation of this highly soluble proteinin vivoremains largely unanswered. Interestingly,in vitroTau can be i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f235895f5a851680bd68990b21361ea5
https://doi.org/10.1523/jneurosci.1920-20.2020
https://doi.org/10.1523/jneurosci.1920-20.2020