Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Katerina, Naydenova"'
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-5 (2017)
A number of parameters influence the resolution of a cryo-EM structure. Here the authors investigate the effects of specimen orientation in single particle cryo-EM and present open-source software for rapidly assessing orientation distributions to im
Externí odkaz:
https://doaj.org/article/e7fc8c59bb4b44a4bf246510f6cb7c7f
Publikováno v:
Faraday Discussions. 240:277-302
Current and future technology for in situ electron cryomicroscopy is considered from theoretical and practical viewpoints.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3e398c0291cb05cfe64b6d55ebb166e3
https://doi.org/10.1039/d2fd00076h
https://doi.org/10.1039/d2fd00076h
Publikováno v:
Faraday discussions. 240
Electron cryomicroscopy (cryoEM) has made great strides in the last decade, such that the atomic structure of most biological macromolecules can, at least in principle, be determined. Major technological advances - in electron imaging hardware, data
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6165ee4b1cb17e773616dea5fecdd560
https://pubmed.ncbi.nlm.nih.gov/35913392
https://pubmed.ncbi.nlm.nih.gov/35913392
Autor:
Andrija Sente, Rooma Desai, Katerina Naydenova, Tomas Malinauskas, Youssef Jounaidi, Jonas Miehling, Xiaojuan Zhou, Simonas Masiulis, Steven W. Hardwick, Dimitri Y. Chirgadze, Keith W. Miller, A. Radu Aricescu
Publikováno v:
Nature
Type-A γ-aminobutyric acid receptors (GABA(A)Rs) are pentameric ligand-gated chloride channels that mediate fast inhibitory signalling in neural circuits( 1,2 ) and are modulated by essential medicines including general anaesthetics and benzodiazepi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72f928e59bd5199c06fca89677a54a4c
https://europepmc.org/articles/PMC7612593/
https://europepmc.org/articles/PMC7612593/
Publikováno v:
Science. 370:223-226
Going for the goldSingle-particle cryogenic electron microscopy (cryo-EM) has become a go-to technique for structural biologists. Although data-processing and reconstruction methods have improved, innovations in sample preparation and data collection
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f39f479a0af3955abfab3da42ef24375
https://doi.org/10.1126/science.abb7927
https://doi.org/10.1126/science.abb7927
Autor:
Pu Qian, Alastair T. Gardiner, Ivana Šímová, Katerina Naydenova, Tristan I. Croll, Philip J. Jackson, null Nupur, Miroslav Kloz, Petra Čubáková, Marek Kuzma, Yonghui Zeng, Pablo Castro-Hartmann, Bart van Knippenberg, Kenneth N. Goldie, David Kaftan, Pavel Hrouzek, Jan Hájek, Jon Agirre, C. Alistair Siebert, David Bína, Kasim Sader, Henning Stahlberg, Roman Sobotka, Christopher J. Russo, Tomáš Polívka, C. Neil Hunter, Michal Koblížek
Publikováno v:
Science Advances
Qian, P, Gardiner, A T, Šímová, I, Naydenova, K, Croll, T I, Jackson, P J, Nupur, Kloz, M, Čubáková, P, Kuzma, M, Zeng, Y, Castro-Hartmann, P, van Knippenberg, B, Goldie, K N, Kaftan, D, Hrouzek, P, Hájek, J, Agirre, J, Siebert, C A, Bína, D, Sader, K, Stahlberg, H, Sobotka, R, Russo, C J, Polívka, T, Hunter, C N & Koblížek, M 2022, ' 2.4-Å structure of the double-ring Gemmatimonas phototrophica photosystem ', Science Advances, vol. 8, no. 7, eabk3139 . https://doi.org/10.1126/sciadv.abk3139
Qian, P, Gardiner, A T, Šímová, I, Naydenova, K, Croll, T I, Jackson, P J, Nupur, Kloz, M, Čubáková, P, Kuzma, M, Zeng, Y, Castro-Hartmann, P, van Knippenberg, B, Goldie, K N, Kaftan, D, Hrouzek, P, Hájek, J, Agirre, J, Siebert, C A, Bína, D, Sader, K, Stahlberg, H, Sobotka, R, Russo, C J, Polívka, T, Hunter, C N & Koblížek, M 2022, ' 2.4-Å structure of the double-ring Gemmatimonas phototrophica photosystem ', Science Advances, vol. 8, no. 7, eabk3139 . https://doi.org/10.1126/sciadv.abk3139
Phototrophic Gemmatimonadetes evolved the ability to use solar energy following horizontal transfer of photosynthesis-related genes from an ancient phototrophic proteobacterium. The electron cryo-microscopy structure of the Gemmatimonas phototrophica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c06c29ec14e41339999696ca8a78ebbe
https://doi.org/10.1126/sciadv.abk3139
https://doi.org/10.1126/sciadv.abk3139
Publikováno v:
Microscopy and Microanalysis. 28:1154-1155
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7b51d2bc57ecb8ecbb8d01d95b60c93e
https://doi.org/10.1017/s1431927622004846
https://doi.org/10.1017/s1431927622004846
Autor:
Y. Lee, Richard Henderson, Shaoxia Chen, Katerina Naydenova, Christopher J. Russo, E. Leahy, M. J. Peet, Greg McMullan, S. Scotcher, Patricia C. Edwards
Publikováno v:
IUCrJ
IUCrJ, Vol 6, Iss 6, Pp 1086-1098 (2019)
IUCrJ, Vol 6, Iss 6, Pp 1086-1098 (2019)
Several structures were determined by single-particle cryoEM at 100 keV and the implications for future electron cryomicroscopes are considered.
100 kV is investigated as the operating voltage for single-particle electron cryomicroscopy (cryoEM)
100 kV is investigated as the operating voltage for single-particle electron cryomicroscopy (cryoEM)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9734ebe04c5b18b180d42b8283aa214
http://europepmc.org/articles/PMC6830209
http://europepmc.org/articles/PMC6830209
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance Single-particle electron cryomicroscopy (cryoEM) has now proved to be the method of choice for determining the structure of biological macromolecules and complexes. Yet success in determining a structure by cryoEM depends on being able t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4dac617f9d299cbd736b7f29c14d9397
https://doi.org/10.1073/pnas.1904766116
https://doi.org/10.1073/pnas.1904766116
Autor:
Long-Fei Wu, Kasim Sader, Pablo Castro-Hartmann, Jan Löwe, Kyle W. Muir, Pu Qian, Dari Kimanius, Francesca Coscia, Kyle Dent, John D. Sutherland, Christopher J. Russo, M. J. Peet, David Barford, Katerina Naydenova, Ziguo Zhang
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences
Proceedings of the National Academy of Sciences
Significance While the current COVID-19 pandemic continues, the US Food and Drug Administration (FDA) has approved only one drug against the virus—remdesivir. It is a nucleotide analogue inhibitor of the SARS-CoV-2 RNA-dependent RNA polymerase; fav
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3e21905789c96124d65b476169d06d7
https://pubmed.ncbi.nlm.nih.gov/33526596
https://pubmed.ncbi.nlm.nih.gov/33526596