Zobrazeno 1 - 10
of 86
pro vyhledávání: '"Kateri A. Moore"'
Autor:
Andreia M. Gomes, Ilia Kurochkin, Betty Chang, Michael Daniel, Kenneth Law, Namita Satija, Alexander Lachmann, Zichen Wang, Lino Ferreira, Avi Ma’ayan, Benjamin K. Chen, Dmitri Papatsenko, Ihor R. Lemischka, Kateri A. Moore, Carlos-Filipe Pereira
Publikováno v:
Cell Reports, Vol 25, Iss 10, Pp 2821-2835.e7 (2018)
Summary: During development, hematopoietic stem and progenitor cells (HSPCs) arise from specialized endothelial cells by a process termed endothelial-to-hematopoietic transition (EHT). The genetic program driving human HSPC emergence remains largely
Externí odkaz:
https://doaj.org/article/59503b1ffe32437e98c4083456bd02ef
Autor:
Sonia Mulero-Navarro, Ana Sevilla, Angel C. Roman, Dung-Fang Lee, Sunita L. D’Souza, Sherly Pardo, Ilan Riess, Jie Su, Ninette Cohen, Christoph Schaniel, Nelson A. Rodriguez, Alessia Baccarini, Brian D. Brown, Hélène Cavé, Aurélie Caye, Marion Strullu, Safak Yalcin, Christopher Y. Park, Perundurai S. Dhandapany, Ge Yongchao, Lisa Edelmann, Sawsan Bahieg, Patrick Raynal, Elisabetta Flex, Marco Tartaglia, Kateri A. Moore, Ihor R. Lemischka, Bruce D. Gelb
Publikováno v:
Cell Reports, Vol 13, Iss 3, Pp 504-515 (2015)
Somatic PTPN11 mutations cause juvenile myelomonocytic leukemia (JMML). Germline PTPN11 defects cause Noonan syndrome (NS), and specific inherited mutations cause NS/JMML. Here, we report that hematopoietic cells differentiated from human induced plu
Externí odkaz:
https://doaj.org/article/9780445694cc446b983bfa504b8a9a71
Publikováno v:
Blood Adv
Hematopoietic cell transplantation is a critical curative approach for many blood disorders. However, obtaining grafts with sufficient numbers of hematopoietic stem cells (HSCs) that maintain long-term engraftment remains challenging; this is due par
Publikováno v:
Ann N Y Acad Sci
The induction of hematopoiesis in various cell types via transcription factor (TF) reprogramming has been demonstrated by several strategies. The eventual goal of these approaches is to generate a product for unmet needs in hematopoietic cell transpl
Autor:
Lino Ferreira, Ilia Kurochkin, Carlos Filipe Pereira, Namita Satija, Ihor R. Lemischka, Benjamin K. Chen, Kenneth Law, Betty Chang, Zichen Wang, Kateri A. Moore, Andreia Gomes, Dmitri Papatsenko, Alexander Lachmann, Avi Ma'ayan, Michael G. Daniel
Publikováno v:
Cell Reports, Vol 25, Iss 10, Pp 2821-2835.e7 (2018)
Cell reports
Cell reports
SUMMARY During development, hematopoietic stem and progenitor cells (HSPCs) arise from specialized endothelial cells by a process termed endothelial-to-hematopoietic transition (EHT). The genetic program driving human HSPC emergence remains largely u
Autor:
Fangming Lin, Jiajing Qiu, Vijay Menon, Jeffrey M. Bernitz, Kateri A. Moore, Raymond Liang, Svetlana Kalmykova, Tasleem Arif, Nikolaos Tzavaras, Miao Lin, Deanna L. Benson, Artem S. Kasianov, Milind Mahajan, Saghi Ghaffari, Dmitri Papatsenko
Publikováno v:
Cell Stem Cell
Summary Quiescence is a fundamental property that maintains hematopoietic stem cell (HSC) potency throughout life. Quiescent HSCs are thought to rely on glycolysis for their energy, but the overall metabolic properties of HSCs remain elusive. Using c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cf225865e367f46559e2f78ec6802ac
https://europepmc.org/articles/PMC8075247/
https://europepmc.org/articles/PMC8075247/
Autor:
Alexander Lachmann, Dmitrii Shcherbinin, Avinash Waghray, Dmitri Papatsenko, Ran Brosh, Kateri A. Moore, Jeffrey M. Bernitz, Avi Ma'ayan, Ye Yuan, Andreia Gomes, Michael G. Daniel, Katrina Rapp
Publikováno v:
Stem Cell Reports
Stem Cell Reports, 14 (4)
Stem Cell Reports, 14 (4)
Summary Hematopoietic stem cells (HSCs) exist in a dormant state and progressively lose regenerative potency as they undergo successive divisions. Why this functional decline occurs and how this information is encoded is unclear. To better understand
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45bddd9255ee71ca761d90f7aa7113e3
Autor:
Jeffrey M. Bernitz, Katrina Rapp, Carlos Filipe Pereira, Namita Satija, David H. Sachs, Michael G. Daniel, Yesai Fstkchyan, Kateri A. Moore, Kenneth Law, Ihor R. Lemischka, Huen Suk Kim, Benjamin K. Chen, Foram Patel, Andreia Gomes
Publikováno v:
FEBS Letters, 593 (23)
FEBS Lett
FEBS Lett
Transcription factor (TF)‐based reprogramming of somatic tissues holds great promise for regenerative medicine. Previously, we demonstrated that the TFs GATA2, GFI1B, and FOS convert mouse and human fibroblasts to hemogenic endothelial‐like precu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b08307f4ad79a520ee16ac30674a7b30
https://hdl.handle.net/20.500.11850/372263
https://hdl.handle.net/20.500.11850/372263
Publikováno v:
Journal of visualized experiments : JoVE. (153)
The cellular and molecular mechanisms underlying specification of human hematopoietic stem cells (HSCs) remain elusive. Strategies to recapitulate human HSC emergence in vitro are required to overcome limitations in studying this complex developmenta
Publikováno v:
Blood. 129:1901-1912
Granulocyte colony-stimulating factor (G-CSF) is used clinically to treat leukopenia and to enforce hematopoietic stem cell (HSC) mobilization to the peripheral blood (PB). However, G-CSF is also produced in response to infection, and excessive expos