Výsledky vyhledávání - "Katelyn Tepper"

Bis-aryl-α,β-unsaturated ketone (ABK) chaperonin inhibitors exhibit selective cytotoxicity to colorectal cancer cells that correlates with levels of aberrant HSP60 in the cytosol

Autor: Siddhi Chitre, Anne-Marie Ray, Mckayla Stevens, Emma H. Doud, Hope Liechty, Alex Washburn, Katelyn Tepper, Jared Sivinski, Heather M. O'Hagan, Millie M. Georgiadis, Eli Chapman, Steven M. Johnson

Publikováno v: Bioorganicmedicinal chemistry. 75

While many studies have established the importance of protein homeostasis in tumor progression, little effort has been made to examine the therapeutic potential of targeting the HSP60 chaperonin system. In healthy cells, HSP60 is localized to the mit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d64170a8200acc1dcd918dae6bc00628
https://pubmed.ncbi.nlm.nih.gov/36356534

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