Výsledky vyhledávání - "Katelyn Russell"

Akademický článek

A mouse model with widespread expression of the C9orf72-linked glycine–arginine dipeptide displays non-lethal ALS/FTD-like phenotypes

Autor: Brandie Morris Verdone, Maria Elena Cicardi, Xinmei Wen, Sindhu Sriramoji, Katelyn Russell, Shashirekha S. Markandaiah, Brigid K. Jensen, Karthik Krishnamurthy, Aaron R. Haeusler, Piera Pasinelli, Davide Trotti

Publikováno v: Scientific Reports, Vol 12, Iss 1, Pp 1-17 (2022)

Abstract Translation of the hexanucleotide G4C2 expansion associated with C9orf72 amyotrophic lateral sclerosis and frontotemporal dementia (ALS/FTD) produces five different dipeptide repeat protein (DPR) species that can confer toxicity. There is ye

Externí odkaz: https://doaj.org/article/19ca21d95d3242fdb4694723b5e2de9e

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Akademický článek

Repeat‐associated non‐AUG translation in C9orf72‐ALS/FTD is driven by neuronal excitation and stress

Autor: Thomas Westergard, Kevin McAvoy, Katelyn Russell, Xinmei Wen, Yu Pang, Brandie Morris, Piera Pasinelli, Davide Trotti, Aaron Haeusler

Publikováno v: EMBO Molecular Medicine, Vol 11, Iss 2, Pp 1-14 (2019)

Abstract Nucleotide repeat expansions (NREs) are prevalent mutations in a multitude of neurodegenerative diseases. Repeat‐associated non‐AUG (RAN) translation of these repeat regions produces mono or dipeptides that contribute to the pathogenesis

Externí odkaz: https://doaj.org/article/357cba24d5134eb4b3da6cedf90a1fe5

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Using a Normothermia Bundle With Perioperative Prewarming to Reduce Patient Hypothermia

Autor: Katelyn Russell, Lois M. Stallings Welden, Marilyn Ostendorf, Jonathan D. Stallings

Publikováno v: Journal of PeriAnesthesia Nursing. 37:114-121

Purpose To determine if implementing a normothermia bundle, which includes preoperative forced-air warming blankets, reduces incidence of inadvertent perioperative hypothermia (IPH). Design Intervention study using retrospective chart review. Methods

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7df22cbebbfc1a765fc4e300b3918422
https://doi.org/10.1016/j.jopan.2021.07.008

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Synaptic dysfunction induced by glycine‐alanine dipeptides in C9orf72‐ ALS / FTD is rescued by SV 2 replenishment

Autor: Katelyn Russell, Ashley Boehringer, Dieter Edbauer, Kevin McAvoy, Brigid K. Jensen, Thomas Westergard, Bridget M. Curran, Le Ma, Martin H Schuldi, Piera Pasinelli, Xinmei Wen, Karthik Krishnamurthy, Aaron R. Haeusler, Davide Trotti

Publikováno v: EMBO molecular medicine 12(5), e10722 (2020). doi:10.15252/emmm.201910722
EMBO Molecular Medicine
EMBO Molecular Medicine, Vol 12, Iss 5, Pp n/a-n/a (2020)

The most common cause of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) is an intronic hexanucleotide repeat expansion in the C9orf72 gene. In disease, RNA transcripts containing this expanded region undergo repeat‐associated

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73196be2a6ddf0e1abed144a6614902a