Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Katelyn R. Ludwig"'
Publikováno v:
Metabolites, Vol 8, Iss 1, p 5 (2018)
Vitamin D deficiency is a common problem worldwide. In particular, it is an issue in the Northern Hemisphere where UVB radiation does not penetrate the atmosphere as readily. There is a correlation between vitamin D deficiency and colorectal cancer i
Externí odkaz:
https://doaj.org/article/40a0776a20c04769b14ed2cb3472201a
Autor:
Abigail G. Longtine, Ravinandan Venkatasubramanian, Melanie C. Zigler, Alexandra J. Lindquist, Sophia A. Mahoney, Nathan T. Greenberg, Nicholas S. VanDongen, Katelyn R. Ludwig, Kerrie L. Moreau, Douglas R. Seals, Zachary S. Clayton
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 324:H893-H904
Our study demonstrates that with aging, female C57BL/6N mice exhibit higher in vivo aortic stiffness, reduced modulus of elasticity, aortic wall structural and extracellular matrix remodeling, and elevations in systemic inflammation. These changes ar
Publikováno v:
Anal Chem
Three-dimensional cell cultures, or spheroids, are important model systems for cancer research because they recapitulate chemical and phenotypic aspects of in vivo tumors. Spheroids develop radially symmetric chemical gradients, resulting in distinct
Autor:
Diego Faria, Renata J. Moll-Bernardes, Laura Testa, Camila M.V. Moniz, Erika C. Rodrigues, Amanda G. Rodrigues, Amanda Araujo, Maria J.N.N. Alves, Bruna E. Ono, João E. Izaias, Vera M.C. Salemi, Camila P. Jordão, Graziela Amaro-Vicente, Maria U.P.B. Rondon, Katelyn R. Ludwig, Daniel H. Craighead, Matthew J. Rossman, Fernanda M. Consolim-Colombo, Katia De Angelis, Maria C.C. Irigoyen, Douglas R. Seals, Carlos E. Negrão, Allan R.K. Sales
Publikováno v:
Hypertension (Dallas, Tex. : 1979).
Background: COVID-19 has become a dramatic health problem during this century. In addition to high mortality rate, COVID-19 survivors are at increased risk for cardiovascular diseases 1-year after infection. Explanations for these manifestations are
Autor:
Tam Vo, Tayvia Brownmiller, Katherine Hall, Tamara L Jones, Sulbha Choudhari, Ioannis Grammatikakis, Katelyn R Ludwig, Natasha J Caplen
Publikováno v:
Nucleic Acids Res
In the presence of physiological monovalent cations, thousands of RNA G-rich sequences can form parallel G-quadruplexes (G4s) unless RNA-binding proteins inhibit, destabilize, or resolve the formation of such secondary RNA structures. Here, we have u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30cedba0b6d0e0efa79b8b4d7eb01775
https://doi.org/10.1101/2022.04.18.488656
https://doi.org/10.1101/2022.04.18.488656
Autor:
Natasha J. Caplen, Katherine L Hall, Tamara L. Jones, Soumya Sundara Rajan, Katelyn R. Ludwig
Publikováno v:
Molecular Carcinogenesis
The year 2021 marks the 20th anniversary of the first publications reporting the discovery of the gene silencing mechanism, RNA interference (RNAi) in mammalian cells. Along with the many studies that delineated the proteins and substrates that form
Autor:
Jeffrey M. Resnick, Emily Cannon, Tonia C. Carter, Katelyn R. Ludwig, Sunil Badve, Steven Buechler, Amanda B. Hummon, Melissa T. Stephens, Yesim Gökmen-Polar
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-13 (2020)
Scientific Reports
Scientific Reports
Colorectal cancer (CRC) tumors can be partitioned into four biologically distinct consensus molecular subtypes (CMS1-4) using gene expression. Evidence is accumulating that tumors in different subtypes are likely to respond differently to treatments.
Autor:
Natasha J. Caplen, Soumya Sundara Rajan, Vernon Ebegboni, Tamara L. Jones, Michael J. Kruhlak, Jan Wisniewski, Patricio Pichling, Katelyn R. Ludwig, Javed Khan, Raj Chari
Publikováno v:
Clinical Cancer Research. 28:B012-B012
EWSR1, a member of the FET protein family, contains low complexity and nucleic acid binding domains and functions in transcription regulation and RNA metabolism. Recent biochemical and EWSR1-depletion studies demonstrated that EWSR1 regulates critica
Autor:
Zachary S, Clayton, Daniel H, Craighead, Sanna, Darvish, McKinley, Coppock, Katelyn R, Ludwig, Vienna E, Brunt, Douglas R, Seals, Matthew J, Rossman
Publikováno v:
The Journal of Cardiovascular Aging. 2:43
The development of age-related cardiovascular (CV) dysfunction increases the risk of CV disease as well as other chronic age-associated disorders, including chronic kidney disease, and Alzheimer’s disease and related dementias. Major manifestations
Publikováno v:
J Am Soc Mass Spectrom
Short-term glucose starvation prior to chemotherapy has the potential to preferentially weaken cancer cells, making them more likely to succumb to treatment, while protecting normal cells. In this study, we used 3D cell cultures of colorectal cancer