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pro vyhledávání: '"Katelyn Purvis"'
Autor:
Corey Falcon, Lauren Smith, Mustafa Al-Obaidi, Mohammed Abu Zaanona, Katelyn Purvis, Kentaro Minagawa, Mohammad Athar, Donna Salzman, Ravi Bhatia, Frederick Goldman, Antonio Di Stasi
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Gene-modified cellular therapies carry inherent risks of severe and potentially fatal adverse events, including the expansion of alloreactive cells or malignant transformation due to insertional mutagenesis. Strategies to mitigate uncontrolled prolif
Externí odkaz:
https://doaj.org/article/e99fceecbd3b44d591957ea26258e876
Autor:
Varun Sikri, Naman Sharma, Kenta Ito, Songjie Gong, Alberto Jeronimo, Venkatesh Natarajan, Sunju Choi, Magdalena Falat, Saurabh Deepak Chitnis, Nell Narasappa, Lalith Namburu, Queenie Qiu, Ankita Batra, Pooja Smruthi Keerthipati, Jason Braun, Hannalei Mae Zamora, Ramakrishnan Gopalakrishnan, Vishan Chaudhary, Hittu Matta, Michael Kahn, Rekha Prakash, Tomas Meza Stieben, Fatima Patel, Ruben Prins, Arta Zenunovic, Preet M. Chaudhary, Supriya Peshin, Allen Membreno, Katelyn Purvis, Dan Wang, Jyotirmayee Lenka, Andrei A. Kochegarov, Jae Han Lee
Publikováno v:
Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-13 (2019)
Scientific Reports, Vol 9, Iss 1, Pp 1-13 (2019)
Chimeric Antigen Receptor-T (CAR-T) cell immunotherapy has produced dramatic responses in hematologic malignancies. One of the challenges in the field is the lack of a simple assay for the detection of CARs on the surface of immune effector cells. In